psoriasis-associated — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0500	Chloroxine	Capitrol	Antibacterial , Antibiotic
	Chloroxine (Capitrol) is a synthetic quinoline derivative with antibacterial activity. Although the mechanism of action is not fully understood, topical administration of chloroxine diminishes mitotic activity in the epi...		Antibacterial , Antibiotic
T76884	Spesolimab	BI 655130	IL Receptor
	Spesolimab (BI 655130) is an anti-interleukin-36 receptor antibody. IL-36 plays an important role in the immune system and is associated with a reduction in biomarkers associated with congenital Th1/Th17 and neutrophil p...		IL Receptor
T77677	12R-LOX-IN-2		Lipoxygenase
	12R-LOX-IN-2 is an inhibitor of 12R-lipoxygenase (12R-LOX).12R-LOX-IN-2 inhibits imiquimod (IMQ)-induced hyperproliferation of psoriatic keratinocytes and inhibits colony formation.12R-LOX-IN-2 also decreases the protein...		Lipoxygenase
T81261	ROCK2-IN-7		ROCK
	ROCK2 inhibitor is a chemical compound associated with the therapeutic management of psoriasis. It exhibits its efficacy in targeting ROCK2 enzymes within HaCaT cells and has demonstrated beneficial effects in a psoriasi...		ROCK
T78298	Alefacept	LFA 3TIP,Human LFA 3IgG fusion protein,BG 9273
	Alefacept (BG 9273), a fusion protein combining human lymphocyte function-associated antigen 3 with immunoglobulin 1, is utilized in the research of chronic plaque psoriasis [1].
T40043	RORγt Inverse agonist 10
	RORγt Inverse agonist 10 is a highly potent and orally bioavailable compound that acts as an antagonist for the retinoic acid receptor-related orphan nuclear receptor gamma t (RORγt). With an IC50 of 51 nM, it effectivel...

Compounds

Chloroxine

T0500

Synonym: Capitrol

Target: Antibacterial, Antibiotic

Synonym: LFA 3TIP,Human LFA 3IgG fusion protein,BG 9273

Target:

RORγt Inverse agonist 10

T40043

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02174	FABP5 Protein, Human, Recombinant	Human	E. coli
	Fatty acid-binding protein, also known as Epidermal-type fatty acid-binding protein, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog, E-FABP and FABP5, is a cytoplasm protein whic...
TMPJ-01073	FABP5 Protein, Human, Recombinant (His)	Human	E. coli
	Fatty acid-binding protein 5 (FABP5) is a cytoplasm protein that belongs to the fatty-acid binding protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytopl...
TMPY-02153	TNF beta Protein, Human, Recombinant	Human	E. coli
	Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lympho...
TMPK-00668	IL-21R Protein, Cynomolgus, Recombinant (aa 41-254, His)	Cynomolgus	HEK293 Cells
	IL-21 and IL-21R were highly expressed in the lesional skin and peripheral blood of psoriasis patients. IL-21 promoted CD4 T cells proliferation and Th17 cells differentiation and inhibiting Treg cells differentiation by...
TMPJ-00351	IL-23R Protein, Human, Recombinant (aa 24-353, hFc)	Human	HEK293 Cells
	Interleukin 23 receptor (IL23R) is a type I cytokine receptor for IL23. IL23 receptor complex is comprised of two subunits, the IL12Rβ1 subunit, which is shared with several cytokines, and a subunit that is unique to IL-...
TMPJ-01219	IL-23R Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Interleukin 23 receptor (IL23R), a heterodimer of the IL12 receptor β1 (IL12Rβ1) and IL12Rβ2, is a type I cytokine receptor for IL23. IL23R is comprised of two subunits, the IL12Rβ1 subunit, which is shared with several ...