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Cat No. | Product Name | Synonyms | Targets |
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T1843 | XMD8-92 | ERK , BMI-1 , Epigenetic Reader Domain | |
XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM). | |||
T14982 | Clofilium tosylate | Potassium Channel | |
Clofilium tosylate is a potassium channel blocker. It induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase-3. | |||
T35554 | GSK-3β inhibitor 3 | Apoptosis , GSK-3 | |
GSK-3β inhibitor 3 is a covalent inhibitor (IC50: 6.6 μM) of glycogen synthase kinase 3β (GSK-3β) that is potent, selective, and irreversible.GSK-3β inhibitor 3 can be used to study acute promyelocytic leukemia. | |||
T31002 | Colletochlorin B | ||
Colletochlorin B is a natural differentiation inducer of human promyelocytic leukemia cells. | |||
T36575 | HDAC3 Inhibitor | ||
HDAC3 inhibitor is an allosteric inhibitor of histone deacetylase 3 (HDAC3; Ki = 0.16 nM). It is selective for HDAC3 over HDAC1 and HDAC2 (IC50s = 0.95, 11.81, and 95.45 nM, respectively, using recombinant HDACs). In add... | |||
T37056 | D-erythro-MAPP | ||
D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 μM; IC50 = 1-5 μM). It is selective for alkaline ceramidase over acid ceramidase (IC50 = >500 μM) as well as the serine/threon... | |||
T19228 | Calcitriol Impurities D | 24-Homo Calcitriol,24-Homo-1,25-dihydroxyvitamin D3 | Antiviral |
Calcitriol Impurities D (24-Homo Calcitriol) is a hormonal form of the vitamin that promotes the differentiation of HL-60 human promyelocytic leukemia cells into monocytes.Calcitriol Impurities D has bone resorption acti... | |||
T36418 | O-Desmethyl-N-deschlorobenzoyl Indomethacin | ||
O-Desmethyl-N-deschlorobenzoyl indomethacin is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor indomethacin .1It is formed from indomethacin in isolated rabbit hepatocytes. O-Desmethyl-... | |||
T36199 | AZD 1152 (hydrochloride) | ||
AZD 1152 is an orally bioavailable prodrug of AZD 1152-HQPA, a selective inhibitor of Aurora kinase B (IC50= 0.36 nM).1AZD 1152 is converted to AZD 1152-HQPA in plasma. Inhibition of Aurora B results in disruption of spi... |
Cat No. | Product Name | Synonyms | Targets |
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TN1684 | Ginsenoside F5 | Apoptosis | |
Ginsenoside F5 is a natural product from Panax ginseng C. A. Mey, remarkably inhibits the growth of HL-60 cells by the apoptosis pathway | |||
TJS0328 | Nordalbergin | 6,7-dihydroxy-4-phenylcoumarin,6,7-Dihydroxy-4-Phenylchromen-2-One | Others |
Nordalbergin is a natural product for research related to life sciences. The catalog number is TJS0328 and the CAS number is 482-82-6. | |||
T6S0234 | Toosendanin | Others | |
1. Toosendanin possesses hepatotoxicity. 2. Toosendanin has effects on the growth, cell cycle arrest, induction of apoptosis and the involved signaling pathway in human promyelocytic leukemia HL-6 cells. 3. Toosendanin i... | |||
TMS0484 | Episyringaresinol 4'-O-β-D-glncopyranoside | (-)-Syringaresinol 4-O-β-D-glucopyranosi | Others |
Episyringaresinol 4'-O-β-D-glncopyranoside ((-)-Syringaresinol 4-O-β-D-glucopyranosi) inhibits the proliferation of human promyelocytic HL-6 cells through G(1) arrest and induction of apoptosis, may be a potential chemot... | |||
TJS0487 | (-)-Syringaresinol | DL-Syringaresinol,Lirioresinol b | Others |
(-)-Syringaresinol (DL-Syringaresinol) is derived from the stems of Annona Montana. (-)-Syringaresinol inhibits the proliferation of human promyelocytic HL-60 cells through G1 arrest and induction of apoptosis and posses... | |||
TN3799 | Dehydrocrebanine | Antifection | |
Dehydrocrebanine has strong activity against promyelocytic leukemia cells (HL-60) with an IC50 of 2.14 ug/mL. It also shows potent antimalarial activity with an IC50 value of 70 ng/ml. | |||
TN2318 | Yadanziolide C | Others | |
Yadanziolide C induces differentiation with cultured HL-60 promyelocytic leukemia cells. | |||
TN3838 | Desmethylrocaglamide | Others | |
Desmethylrocaglamide is a novel inducer of cellular differentiation using HL-60 promyelocytic cells, it may be a drug for the prevention and therapy of cancer. It also has insecticidal activity. | |||
TN6054 | Norglaucine hydrochloride | ||
(+)-Norglaucine shows cytotoxic activity toward the tumor cell lines B16-F10 (mouse melanoma), HepG2 (human hepatocellular carcinoma), K562 (human chronic myelocytic leukemia) and HL-60 (human promyelocytic leukemia) and... | |||
T37442 | Aspergillin PZ | ||
Aspergillin PZ is a fungal metabolite originally isolated from A. awamori. It induces morphological deformation of P. oryzae conidia when used at a concentration of 89 nM. Aspergillin PZ is active against S. epidermidis ... | |||
T14304 | Aphidicolin | Others | |
Aphidicolin is a potent inhibitor of cellular deoxyribonucleic acid synthesis and inhibits the growth of herpes simplex virus[2]. Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by i... |
Cat No. | Product Name | Species | Expression System |
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TMPY-01483 | SLAMF7 Protein, Human, Recombinant (His) | Human | HEK293 |
SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 ... | |||
TMPJ-00844 | ANXA8 Protein, Human, Recombinant | Human | E. coli |
Annexin A8 (ANXA8) belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Annexin A8 contains 4 annexin repeats separated by linking sequences of variable lengths. A pair of annexin repeats ... | |||
TMPJ-00677 | TGOLN2 Protein, Human, Recombinant (His) | Human | Human Cells |
This protein may be involved in regulating membrane traffic to and from trans-Golgi network. Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed i... | |||
TMPK-01395 | TENM2 Protein, Human, Recombinant (His) | Human | HEK293 |
Teneurin-2 is a member of a novel family of transmembrane proteins characterized to date in fish, birds, mammals, and Drosophila (e.g., the pair-rule gene product Ten-m). Teneurin-2, a vertebrate homologue of the Drosoph... | |||
TMPY-05547 | SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated | Human | HEK293 |
SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 ... | |||
TMPJ-01442 | SLAMF7 Protein, Rhesus macaque, Recombinant (His) | Rhesus Macaque | Human Cells |
SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF7 is expressed in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-cell lines, or T-c... | |||
TMPY-03487 | NRAS Protein, Human, Recombinant (His) | Human | E. coli |
NRAS was discovered by researchers at the Institute of Cancer Research, funded by the Cancer Research Campaign (now Cancer Research UK). NRAS gene is a member of the Ras gene family. It is mapped on chromosome 1, and it ... | |||
TMPJ-00222 | SLAMF7 Protein, Human, Recombinant (mFc) | Human | Human Cells |
SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF7 is expressed in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-cell lines, or T-c... | |||
TMPY-04421 | FES Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
Proto-oncogene tyrosine-protein kinase Fes/Fps, also known as Proto-oncogene c-Fes, Proto-oncogene c-Fps, Feline sarcoma oncogene, FES and FPS, is a protein which contains oneFCH domain, oneprotein kinase domain and o... | |||
TMPJ-00221 | SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | Human Cells |
SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF7 is expressed in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-cell lines, or T-c... | |||
TMPY-05387 | SLAMF7 Protein, Human, Recombinant (hFc) | Human | HEK293 |
SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 ... | |||
TMPY-04385 | ZIP Kinase/DAPK3 Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
Death-associated protein kinase 3, also known as DAP kinase 3, ZIP-kinase, DAPK3 and ZIPK, is a nucleus and cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser/Thr protein kinase family and DAP ... | |||
TMPY-01213 | SLAMF7 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 ... | |||
TMPY-05548 | SLAMF7 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 ... | |||
TMPH-02053 | RBM14 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'-linked polyubiquitination. Cooperates with the E2 CDC34 and the SCF(FBXW11)... |