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Search Results for " promyelocytic "

Targets

9

Compounds

11

Natural Products

15

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T1843 XMD8-92 ERK , BMI-1 , Epigenetic Reader Domain
XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).
T14982 Clofilium tosylate Potassium Channel
Clofilium tosylate is a potassium channel blocker. It induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase-3.
T35554 GSK-3β inhibitor 3 Apoptosis , GSK-3
GSK-3β inhibitor 3 is a covalent inhibitor (IC50: 6.6 μM) of glycogen synthase kinase 3β (GSK-3β) that is potent, selective, and irreversible.GSK-3β inhibitor 3 can be used to study acute promyelocytic leukemia.
T31002 Colletochlorin B
Colletochlorin B is a natural differentiation inducer of human promyelocytic leukemia cells.
T36575 HDAC3 Inhibitor
HDAC3 inhibitor is an allosteric inhibitor of histone deacetylase 3 (HDAC3; Ki = 0.16 nM). It is selective for HDAC3 over HDAC1 and HDAC2 (IC50s = 0.95, 11.81, and 95.45 nM, respectively, using recombinant HDACs). In add...
T37056 D-erythro-MAPP
D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 μM; IC50 = 1-5 μM). It is selective for alkaline ceramidase over acid ceramidase (IC50 = >500 μM) as well as the serine/threon...
T19228 Calcitriol Impurities D 24-Homo Calcitriol,24-Homo-1,25-dihydroxyvitamin D3 Antiviral
Calcitriol Impurities D (24-Homo Calcitriol) is a hormonal form of the vitamin that promotes the differentiation of HL-60 human promyelocytic leukemia cells into monocytes.Calcitriol Impurities D has bone resorption acti...
T36418 O-Desmethyl-N-deschlorobenzoyl Indomethacin
O-Desmethyl-N-deschlorobenzoyl indomethacin is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor indomethacin .1It is formed from indomethacin in isolated rabbit hepatocytes. O-Desmethyl-...
T36199 AZD 1152 (hydrochloride)
AZD 1152 is an orally bioavailable prodrug of AZD 1152-HQPA, a selective inhibitor of Aurora kinase B (IC50= 0.36 nM).1AZD 1152 is converted to AZD 1152-HQPA in plasma. Inhibition of Aurora B results in disruption of spi...
Cat No. Product Name Synonyms Targets
TN1684 Ginsenoside F5 Apoptosis
Ginsenoside F5 is a natural product from Panax ginseng C. A. Mey, remarkably inhibits the growth of HL-60 cells by the apoptosis pathway
TJS0328 Nordalbergin 6,7-dihydroxy-4-phenylcoumarin,6,7-Dihydroxy-4-Phenylchromen-2-One Others
Nordalbergin is a natural product for research related to life sciences. The catalog number is TJS0328 and the CAS number is 482-82-6.
T6S0234 Toosendanin Others
1. Toosendanin possesses hepatotoxicity. 2. Toosendanin has effects on the growth, cell cycle arrest, induction of apoptosis and the involved signaling pathway in human promyelocytic leukemia HL-6 cells. 3. Toosendanin i...
TMS0484 Episyringaresinol 4'-O-β-D-glncopyranoside (-)-Syringaresinol 4-O-β-D-glucopyranosi Others
Episyringaresinol 4'-O-β-D-glncopyranoside ((-)-Syringaresinol 4-O-β-D-glucopyranosi) inhibits the proliferation of human promyelocytic HL-6 cells through G(1) arrest and induction of apoptosis, may be a potential chemot...
TJS0487 (-)-Syringaresinol DL-Syringaresinol,Lirioresinol b Others
(-)-Syringaresinol (DL-Syringaresinol) is derived from the stems of Annona Montana. (-)-Syringaresinol inhibits the proliferation of human promyelocytic HL-60 cells through G1 arrest and induction of apoptosis and posses...
TN3799 Dehydrocrebanine Antifection
Dehydrocrebanine has strong activity against promyelocytic leukemia cells (HL-60) with an IC50 of 2.14 ug/mL. It also shows potent antimalarial activity with an IC50 value of 70 ng/ml.
TN2318 Yadanziolide C Others
Yadanziolide C induces differentiation with cultured HL-60 promyelocytic leukemia cells.
TN3838 Desmethylrocaglamide Others
Desmethylrocaglamide is a novel inducer of cellular differentiation using HL-60 promyelocytic cells, it may be a drug for the prevention and therapy of cancer. It also has insecticidal activity.
TN6054 Norglaucine hydrochloride
(+)-Norglaucine shows cytotoxic activity toward the tumor cell lines B16-F10 (mouse melanoma), HepG2 (human hepatocellular carcinoma), K562 (human chronic myelocytic leukemia) and HL-60 (human promyelocytic leukemia) and...
T37442 Aspergillin PZ
Aspergillin PZ is a fungal metabolite originally isolated from A. awamori. It induces morphological deformation of P. oryzae conidia when used at a concentration of 89 nM. Aspergillin PZ is active against S. epidermidis ...
T14304 Aphidicolin Others
Aphidicolin is a potent inhibitor of cellular deoxyribonucleic acid synthesis and inhibits the growth of herpes simplex virus[2]. Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by i...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01483 SLAMF7 Protein, Human, Recombinant (His) Human HEK293
SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 ...
TMPJ-00844 ANXA8 Protein, Human, Recombinant Human E. coli
Annexin A8 (ANXA8) belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Annexin A8 contains 4 annexin repeats separated by linking sequences of variable lengths. A pair of annexin repeats ...
TMPJ-00677 TGOLN2 Protein, Human, Recombinant (His) Human Human Cells
This protein may be involved in regulating membrane traffic to and from trans-Golgi network. Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed i...
TMPK-01395 TENM2 Protein, Human, Recombinant (His) Human HEK293
Teneurin-2 is a member of a novel family of transmembrane proteins characterized to date in fish, birds, mammals, and Drosophila (e.g., the pair-rule gene product Ten-m). Teneurin-2, a vertebrate homologue of the Drosoph...
TMPY-05547 SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated Human HEK293
SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 ...
TMPJ-01442 SLAMF7 Protein, Rhesus macaque, Recombinant (His) Rhesus Macaque Human Cells
SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF7 is expressed in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-cell lines, or T-c...
TMPY-03487 NRAS Protein, Human, Recombinant (His) Human E. coli
NRAS was discovered by researchers at the Institute of Cancer Research, funded by the Cancer Research Campaign (now Cancer Research UK). NRAS gene is a member of the Ras gene family. It is mapped on chromosome 1, and it ...
TMPJ-00222 SLAMF7 Protein, Human, Recombinant (mFc) Human Human Cells
SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF7 is expressed in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-cell lines, or T-c...
TMPY-04421 FES Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Proto-oncogene tyrosine-protein kinase Fes/Fps, also known as Proto-oncogene c-Fes, Proto-oncogene c-Fps, Feline sarcoma oncogene, FES and FPS, is a protein which contains oneFCH domain, oneprotein kinase domain and o...
TMPJ-00221 SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated Human Human Cells
SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF7 is expressed in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-cell lines, or T-c...
TMPY-05387 SLAMF7 Protein, Human, Recombinant (hFc) Human HEK293
SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 ...
TMPY-04385 ZIP Kinase/DAPK3 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
Death-associated protein kinase 3, also known as DAP kinase 3, ZIP-kinase, DAPK3 and ZIPK, is a nucleus and cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser/Thr protein kinase family and DAP ...
TMPY-01213 SLAMF7 Protein, Mouse, Recombinant (His) Mouse HEK293
SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 ...
TMPY-05548 SLAMF7 Protein, Human, Recombinant (His), Biotinylated Human HEK293
SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 ...
TMPH-02053 RBM14 Protein, Human, Recombinant (His & SUMO) Human E. coli
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'-linked polyubiquitination. Cooperates with the E2 CDC34 and the SCF(FBXW11)...
SLAMF7 Protein, Human, Recombinant (His)
TMPY-01483
Species: Human
Expression System: HEK293
ANXA8 Protein, Human, Recombinant
TMPJ-00844
Species: Human
Expression System: E. coli
TGOLN2 Protein, Human, Recombinant (His)
TMPJ-00677
Species: Human
Expression System: Human Cells
TENM2 Protein, Human, Recombinant (His)
TMPK-01395
Species: Human
Expression System: HEK293
SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated
TMPY-05547
Species: Human
Expression System: HEK293
SLAMF7 Protein, Rhesus macaque, Recombinant (His)
TMPJ-01442
Species: Rhesus Macaque
Expression System: Human Cells
NRAS Protein, Human, Recombinant (His)
TMPY-03487
Species: Human
Expression System: E. coli
SLAMF7 Protein, Human, Recombinant (mFc)
TMPJ-00222
Species: Human
Expression System: Human Cells
FES Protein, Human, Recombinant (His & GST)
TMPY-04421
Species: Human
Expression System: Baculovirus-Insect Cells
SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00221
Species: Human
Expression System: Human Cells
SLAMF7 Protein, Human, Recombinant (hFc)
TMPY-05387
Species: Human
Expression System: HEK293
ZIP Kinase/DAPK3 Protein, Human, Recombinant (GST)
TMPY-04385
Species: Human
Expression System: Baculovirus-Insect Cells
SLAMF7 Protein, Mouse, Recombinant (His)
TMPY-01213
Species: Mouse
Expression System: HEK293
SLAMF7 Protein, Human, Recombinant (His), Biotinylated
TMPY-05548
Species: Human
Expression System: HEK293
RBM14 Protein, Human, Recombinant (His & SUMO)
TMPH-02053
Species: Human
Expression System: E. coli
TargetMol