Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • Histone Methyltransferase
    (5)
  • Apoptosis
    (1)
  • Others
    (2)
Filter
Search Result
Results for "

prmt5-in-4

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    11
    TargetMol | Inhibitors_Agonists
PRMT5-IN-4
PRMT5-IN-4
T39008152615-84-4
PRMT5-IN-4 (compound AAA-1) is a PRMT5 inhibitor. This chemical compound specifically impedes the activity of PRMT5, an enzyme involved in the methylation of arginine residues on target proteins, which plays a critical role in various cellular processes.
  • Inquiry Price
Size
QTY
PRMT5-IN-45
T200980
PRMT5-IN-45 (compound 36) is a potent and selective inhibitor of PRMT5, exhibiting an IC50 value of 3 nM. This compound effectively reduces the levels of symmetrical dimethylarginine (sDMA) and inhibits the proliferation of the MOLM-13 cell line by inducing apoptosis and causing cell cycle arrest.
  • Inquiry Price
Size
QTY
PRMT5-IN-49
T204169428853-17-2
PRMT5-IN-49 (Compound 4b16) is an inhibitor of PRMT5.
  • Inquiry Price
10-14 weeks
Size
QTY
PRMT5-IN-47
T2046283065081-87-7
PRMT5-IN-47 (compound 20) is a potent, selective, and orally active MTA co-operative PRMT5 inhibitor, with an IC50 value of 15 nM. It exhibits antiproliferative and anticancer activity.
  • Inquiry Price
10-14 weeks
Size
QTY
PRMT5-IN-46
T204746380192-76-7
PRMT5-IN-46 (compound 278) inhibits PRMT5 with an IC50 range of 1.001-10.000 μM. PRMT5 is a methyltransferase associated with specific genetic alterations. PRMT5-IN-46 is applicable in the study of proliferative diseases, metabolic disorders, and hematological conditions.
  • Inquiry Price
10-14 weeks
Size
QTY
PRMT5-IN-48
T2054562640287-77-8
PRMT5-IN-48 (compound D3) is an orally active PRMT5 inhibitor with an IC50 of 20.7 nM, displaying antitumor activity. It effectively suppresses the growth of various cancer cells, induces apoptosis, and causes cell cycle arrest at the G0 G1 phase. PRMT5-IN-48 is applicable for research in non-Hodgkin's lymphoma (NHL).
  • Inquiry Price
10-14 weeks
Size
QTY
PRMT5-IN-41
T884903034034-32-4
PRMT5-IN-41 (compound 130) is an effective orally active inhibitor of PRMT5. It inhibits the hERG ion channel with an IC50 of 1.36 µM.
  • Inquiry Price
10-14 weeks
Size
QTY
PRMT5-IN-40
T885103034034-95-9
PRMT5-IN-40 (compound 104) is an effective inhibitor of PRMT5.
  • Inquiry Price
10-14 weeks
Size
QTY
PRMT5-IN-44
T885313034746-35-2
PRMT5-IN-44 (compound 12) is an inhibitor of PRMT5, specifically utilized in cancer research.
  • Inquiry Price
10-14 weeks
Size
QTY
PRMT5-IN-43
T886043034746-11-4
PRMT5-IN-43 (compound 4A) is an inhibitor of PRMT5, primarily utilized in cancer research.
  • Inquiry Price
10-14 weeks
Size
QTY
GSK 591 dihydrochloride
T369812320953-89-5
Potent and selective PRMT5 inhibitor (IC50 = 4 nM). Selective for PRMT5 over a panel of other PRMTs and lysine methyltransferases. Inhibits proliferation of mantle cell lymphoma (MCL) in vitro. To request the negative control for GSK 591, please fill out the SGC 2096 request form on the SGC website.
  • Inquiry Price
Size
QTY