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Search Results for " primary "

Targets

386

Compounds

86

Natural Products

463

Recombinant Proteins

2

Libraries

Cat No. Product Name Synonyms Targets
T6793 BRD7552 Others
BRD7552 is an inducer of transcription factor PDX1, which increases insulin expression. BRD7552 increases PDX1 expression in mouse αTC cells but not βTC cells.
T12115 MSC2360844 PI3K
MSC2360844 is a potent, orally active and selective inhibitor of PI3Kδ(IC50 of 145 nM).
T8779 HBT1 GluR
HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons. HBT1 binds to ligand-binding domain of AMPA-R in glutamate...
T4277 Osilodrostat LCI699 Glucocorticoid Receptor , Others , Hydroxylase
Osilodrostat (LCI699) (LCI699) is an effective inhibitor of human 11β-hydroxylase (IC50: 2.5 nM) and aldosterone synthase (IC50: 0.7 nM).
TD0101 AQC 6-Aminoquinolyl-N-hydroxysccinimidyl carbamate Others
AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) is a reagent for the fluorescence detection of amino acid or protein sequence by HPLC. AQC reacts with primary and sec...
T9149 2BAct 2B-Act,2B Act PERK
2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress response
T3978 Linerixibat GSK2330672,Iinerixibat HBV
Linerixibat (GSK2330672) is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM). It can lower glucose in an animal model of type 2 diabetes and shows excellent developability properties.
T1684 Nitisinone NTBC,SC0735,Nitisone Others , Reactive Oxygen Species
Nitisinone (SC0735)(SC0735) is an enzyme 4-hydroxyphenylpyruvate dioxygenase inhibitor.
T3184 Kevetrin hydrochloride Thioureidobutyronitrile HCl,thioureido butyronitrile hydrochloride,4-Isothioureidobutyronitrile hydrochloride Mdm2 , p53
Kevetrin hydrochloride (4-Isothioureidobutyronitrile hydrochloride) is a small molecule and activator of the tumor suppressor protein p53, with potential antineoplastic activity.
T21510 PSI Proteasome
PSI is a proteasome inhibitor.
T34914 Trabodenoson INNO-8875,INO-8875,PJ875,PJ-875,INNO 8875,INNO8875,PJ 875 Adenosine Receptor
Trabodenoson (INO-8875) is a selective and potent adenosine A1 receptor agonist, an adenosine analog, for the study of primary open-angle glaucoma.
T25006 AGI-14100 AGI 14100 Dehydrogenase
AGI-14100 is a novel and orally available mIDH1 inhibitor.AGI-14100 is used for the treatment of primary human myeloid leukemia.
T77621 Z16078526 p38 MAPK , Mitochondrial Metabolism
Z16078526 enhances thermogenesis in mice by inducing endogenous Ucp1 expression, promoting p38 MAPK phosphorylation, and stimulating lipolysis in primary mouse brown adipocytes. Additionally, it activates thermogenic gen...
T24865 Tenivastatin L-654969,L654969,Simvastatin acid,L 654969,Simvastatin hydroxy acid ROS , HMG-CoA Reductase
Tenivastatin (Simvastatin acid) is an anti-hyperlipidemic HMG-CoA reductase inhibitor that inhibits the production of reactive oxygen species (ROS) and can be used in the study of primary hyperlipidemia.
T18902 6-FAM 6-Carboxyfluorescein Others
6-Carboxyfluorescein (6-FAM) contains a carboxylic acid functional group, facilitating reactions with primary amines through carbodiimide activation.
T7363 Ibuprofen Piconol U75630 Others
Ibuprofen Piconol (U75630) is a non-steroidal, anti-inflammatory (NSAID) agent for the topical relief of primary thermal burns and sunburns.Ibuprofen piconol is a Pyridyl ester of ibuprofen.
T7317 CU-CPT-9a TLR
CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM), that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells-
T24159 IHR-1 IHR 1 Smo
IHR-1 is a Potent Smo antagonist (IC50 = 7.6 nM). Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro.
T23215L (R)-3,4-DCPG HCl (R)-3,4-DCPG HCl(201730-10-1 Free base) GluR
(R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord.
T21743L Beta-Lipotropin (1-10), porcine Acetate Beta-Lipotropin (1-10), porcine Acetate(77875-68-4 Free base) Others
Beta-Lipotropin (1-10), porcine Acetate (Beta-Lipotropin ) (beta-LPH) was found to contain within its C-terminal sequence the primary structure of these peptides.
T3106 C-DIM12 Apoptosis , Others
C-DIM12 induced expression of Nurr1-regulated genes. C-DIM12 increased expression of transfected human Nurr1, induced Nurr1 protein expression in primary dopaminergic neurons and enhanced neuronal survival from exposure ...
T18895 5(6)-FAM SE 5(6)-Carboxyfluorescein N-hydroxysuccinimide ester Others
5(6)-FAM SE (5(6)-Carboxyfluorescein N-hydroxysuccinimide ester) is an amine-reactive green fluorescent dye. 5(6)-FAM SE is widely used for labeling proteins or other molecules that contain a primary or secondary aliphat...
T77717 AST 7062601 AST070 Others
AST 7062601 is a potent Ucp1 inducer that promotes endogenous Ucp1 expression in primary mouse brown adipocytes.AST 7062601 may be useful in the study of obesity.
T18893 5(6)-Carboxyfluorescein 5-(and-6)-Carboxyfluorescein mixed isomers,5(6)-FAM Others
5(6)-Carboxyfluorescein (5-(and-6)-Carboxyfluorescein mixed isomers) contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid.
T25125 AZA197 AZA 197,AZA-197 CDK
AZA197 (AZA-197) is a selective Cdc42 inhibitor. It acts by inhibiting primary colon cancer growth and prolonging survival in a preclinical mouse xenograft model by downregulation of PAK1 activity.
T3069 AZD-1480 JAK
AZD1480 is a novel ATP-competitive JAK2 inhibitor (IC50: 0.26 nM), selectivity act against Tyk2 and JAK3, and to a smaller extent against JAK1. AZD1480 has been used in trials studying the treatment of Solid Malignancies...
T34573 SCH-900271 SCH 900271 AChR
SCH-900271 is a potent nicotinic acid receptor for the treatment of dyslipidaemia and is commonly used in the study of mixed hyperlipidaemia and primary hypercholesterolaemia.
T18990 Fluorescamine Ro 20-7234 Others
Fluorescamine (Ro 20-7234) ( Ro 20-7234) is not fluorescent itself but reacts with primary amines to form highly fluorescent products. It is used to detect amines and peptides.
TP1915 Boc-MLF Others
Antagonist of formyl peptide receptor 1 (FPR1). Reduces superoxide production induced by fMLF with an EC50 of 0.63 μM. Almost completely blocks fMLF-stimulated primary granule exocytosis.
T72984 (Rac)-SHIN2 Others
(Rac)-SHIN2 is a serine hydroxymethyltransferase (SHMT) inhibitor that enhances NOTCH1-driven in vivo survival of primary T-ALL in mice and can be used to study T-cell acute lymphoblastic leukemia (T-ALL).
T64334 Glycolithocholic acid, sodium salt Others
Glycolithocholic acid sodium salt, the sodium form of Glycolithocholic acid, is a glycine-conjugated secondary bile acid utilized in diagnosing ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH), and primary s...
T64351 GI-560192 RL-0070933 Smo
GI-560192 (RL-0070933) is a potent smo cilial modulator with an EC50 value of 0.02 µM. GI-560192 modulates the translocation and/or accumulation of smoothened to the primary cilia by hedgehog signaling pathway.
T0255 Clomipramine hydrochloride Clomipramine HCl,Anafranil Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine , GST
Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demeth...
T18728 Sulfo-SMCC sodium Others
Sulfo-SMCC sodium, a widely utilized non-cleavable, hetero-bifunctional crosslinker for antibody-drug conjugates (ADCs), features both N-hydroxysuccinimide (NHS) ester and maleimide groups. These functionalities enable i...
T60325 Viloxazine Emovit,Viloxazin 5-HT Receptor , Norepinephrine
Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity towards 5-HT 2C receptors while acting as an antagonist for 5-HT 2...
T18967 Dansyl chloride DNSCl Others
Dansyl chloride (DNSC-l) reacts with primary amino groups in both aliphatic and aromatic amines to produce stable blue- or blue-green-fluorescent sulfonamide adducts. It is widely used to modify amino acids, specifically...
T9853 STING activator Compound 53 STING
STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint cons...
T14965 Ciliobrevin D ATPase , Hedgehog/Smoothened
Ciliobrevin D is a AAA+ ATPase motor cytoplasmic dynein inhibitor. Ciliobrevin D inhibits Hedgehog (Hh) signaling and primary cilia formation and it also inhibits dynein-dependent microtubule gliding and ATPase activity ...
T19450 N-desmethyl Enzalutamide N-desmethyl MDV 3100 Androgen Receptor
N-desmethyl Enzalutamide (N-desmethyl MDV 3100) is the active Enzalutamide metabolite.It is the active metabolite of Enzalutamide. N-desmethyl Enzalutamide demonstrates primary and secondary pharmacodynamics of similar p...
T10981 DCZ0415 Apoptosis , Others , NF-κB
DCZ0415 induces antimyeloma activity in vitro, in vivo and in primary cells of drug-resistant myeloma patients. DCZ0415 is a potent TRIP13 inhibitor that can impair the repair of non-homologous end junctions and inhibit ...
T16510 PF-915275 Dehydrogenase
The dose-dependent effect of PF-915275 on the conversion of cortisone to cortisol in primary human and monkey hepatocytes (EC50: 20 and 100 nM, respectively). PF-915275 is an effective and selective human 11β-hydroxyster...
T36866 3-Deazauridine NSC 126849 Nucleoside Antimetabolite/Analog
3-Deazauridine (NSC-126849) is a structural analog of uridine that inhibits the biosynthesis of Cytidine-5'-Triphosphate by competitive inhibition of Cytidine Triphosphate synthetase which is considered to be the primary...
T76700 Simtuzumab GS 6624,AB 0024 Monoamine Oxidase
Simtuzumab is a monoclonal antibody against lysyl oxidase-like protein 2 (LOXL2). Simtuzumab can be used to treat primary sclerosing cholangitis (PSC) and is not effective in patients with bridging fibrosis or compensato...
TP1913L1 BA 1 acetate(183241-31-8 free base) Bombesin Receptor
BA 1 acetate is a potent bombesin receptor agonist (IC50 values are 0.26, 1.55 and 2.52 nM for BB1, BB2 and BB3 respectively). Enhances glucose transport in obese and diabetic primary myocytes. Also stimulates NCI-H1299 ...
T60952 Fluridone EL-171 Others
Fluridone (EL-171) is a potent inhibitor of abscisic acid (ABA) synthesis, inhibits the expression of AchnFAR and TF genes, and reduces the formation of primary alcohol. Fluridone is often used as an aquatic herbicide to...
T14050 5-FAM 5-Carboxyfluorescein Others
5-FAM (5-Carboxyfluorescein) (5-Carboxyfluorescein) contains a carboxylic acid, which can be used to react with primary amines via carbodiimide activation of the carboxylic acid. Fluorescein is the most common fluorescen...
T27586 IDX184 IDX-184,IDX 184 HCV Protease
IDX184 is a potent, orally active, targeted HCV polymerase inhibitor and nucleoside polymerase.IDX184 effectively inhibits HCV polymerase (IC50=0.31 μM, Ki=52.3 nM). IDX184 is a liver-targeted nucleotide prodrug with ant...
T60857 MKK7-COV-9 Others
MKK7-COV-9 is a selective and potent covalent inhibitor of MKK7 with inhibitory effects on MKK7-induced protein-protein interactions.MKK7-COV-9 interrupts the activation of primary B-cells in response to LPS.MKK7-COV-9 s...
T7218 Endomorphin 2 Opioid Receptor
Endomorphins-2 (EM-2) could decrease both the frequency and amplitude of the sEPSC of the motoneurons in lamina IX, which was reversed by the MOR antagonist CTOP. EM-2-IR fibers originated from primary afferent fibers f...
T78362 Transglutaminase TG
Transglutaminase (TG) is a thiolase that induces intermolecular cross-linking of proteins, by catalysing the formation of isopeptide bonds between the γ-carboxamide group of glutamine residues and the primary ε-amine gro...

Compounds

BRD7552
T6793
Synonym:
Target: Others
MSC2360844
T12115
Synonym:
Target: PI3K
HBT1
T8779
Synonym:
Target: GluR
Osilodrostat
T4277
Synonym: LCI699
Target: Glucocorticoid Receptor, Others, Hydroxylase
AQC
TD0101
Synonym: 6-Aminoquinolyl-N-hydroxysccinimidyl carbamate
Target: Others
2BAct
T9149
Synonym: 2B-Act,2B Act
Target: PERK
Linerixibat
T3978
Synonym: GSK2330672,Iinerixibat
Target: HBV
Nitisinone
T1684
Synonym: NTBC,SC0735,Nitisone
Target: Others, Reactive Oxygen Species
Kevetrin hydrochloride
T3184
Synonym: Thioureidobutyronitrile HCl,thioureido butyronitrile hydrochloride,4-Isothioureidobutyronitrile hydrochloride
Target: Mdm2, p53
PSI
T21510
Synonym:
Target: Proteasome
Trabodenoson
T34914
Synonym: INNO-8875,INO-8875,PJ875,PJ-875,INNO 8875,INNO8875,PJ 875
Target: Adenosine Receptor
AGI-14100
T25006
Synonym: AGI 14100
Target: Dehydrogenase
Z16078526
T77621
Synonym:
Target: p38 MAPK, Mitochondrial Metabolism
Tenivastatin
T24865
Synonym: L-654969,L654969,Simvastatin acid,L 654969,Simvastatin hydroxy acid
Target: ROS, HMG-CoA Reductase
6-FAM
T18902
Synonym: 6-Carboxyfluorescein
Target: Others
Ibuprofen Piconol
T7363
Synonym: U75630
Target: Others
CU-CPT-9a
T7317
Synonym:
Target: TLR
IHR-1
T24159
Synonym: IHR 1
Target: Smo
(R)-3,4-DCPG HCl
T23215L
Synonym: (R)-3,4-DCPG HCl(201730-10-1 Free base)
Target: GluR
Beta-Lipotropin (1-10), porcine Acetate
T21743L
Synonym: Beta-Lipotropin (1-10), porcine Acetate(77875-68-4 Free base)
Target: Others
C-DIM12
T3106
Synonym:
Target: Apoptosis, Others
5(6)-FAM SE
T18895
Synonym: 5(6)-Carboxyfluorescein N-hydroxysuccinimide ester
Target: Others
AST 7062601
T77717
Synonym: AST070
Target: Others
5(6)-Carboxyfluorescein
T18893
Synonym: 5-(and-6)-Carboxyfluorescein mixed isomers,5(6)-FAM
Target: Others
AZA197
T25125
Synonym: AZA 197,AZA-197
Target: CDK
AZD-1480
T3069
Synonym:
Target: JAK
SCH-900271
T34573
Synonym: SCH 900271
Target: AChR
Fluorescamine
T18990
Synonym: Ro 20-7234
Target: Others
Boc-MLF
TP1915
Synonym:
Target: Others
(Rac)-SHIN2
T72984
Synonym:
Target: Others
Glycolithocholic acid, sodium salt
T64334
Synonym:
Target: Others
GI-560192
T64351
Synonym: RL-0070933
Target: Smo
Clomipramine hydrochloride
T0255
Synonym: Clomipramine HCl,Anafranil
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine, GST
Sulfo-SMCC sodium
T18728
Synonym:
Target: Others
Viloxazine
T60325
Synonym: Emovit,Viloxazin
Target: 5-HT Receptor, Norepinephrine
Dansyl chloride
T18967
Synonym: DNSCl
Target: Others
STING activator Compound 53
T9853
Synonym:
Target: STING
Ciliobrevin D
T14965
Synonym:
Target: ATPase, Hedgehog/Smoothened
N-desmethyl Enzalutamide
T19450
Synonym: N-desmethyl MDV 3100
Target: Androgen Receptor
DCZ0415
T10981
Synonym:
Target: Apoptosis, Others, NF-κB
PF-915275
T16510
Synonym:
Target: Dehydrogenase
3-Deazauridine
T36866
Synonym: NSC 126849
Target: Nucleoside Antimetabolite/Analog
Simtuzumab
T76700
Synonym: GS 6624,AB 0024
Target: Monoamine Oxidase
BA 1 acetate(183241-31-8 free base)
TP1913L1
Synonym:
Target: Bombesin Receptor
Fluridone
T60952
Synonym: EL-171
Target: Others
5-FAM
T14050
Synonym: 5-Carboxyfluorescein
Target: Others
IDX184
T27586
Synonym: IDX-184,IDX 184
Target: HCV Protease
MKK7-COV-9
T60857
Synonym:
Target: Others
Endomorphin 2
T7218
Synonym:
Target: Opioid Receptor
Transglutaminase
T78362
Synonym: TG
Target:
1 2 3 4 5 6 7 8
Cat No. Product Name Synonyms Targets
T31964 Glycolithocholic acid Lithocholic acid glycine conjugate,Lithocholylglycine Others
Glycolithocholic acid (Lithocholic acid glycine conjugate) is a glycine conjugate of lithocholic acid.
T1882 Meisoindigo N-Methylisoindigotin,Methylisoindigotin,Natura-α,Dian III Apoptosis
Meisoindigo (Natura-α) is a derivative of indigo natural, might induces apoptosis and myeloid differentiation of acute myeloid leukemia (AML).
T4759 Urocanic acid 4-Imidazoleacrylic acid Others , Endogenous Metabolite
Urocanic acid (4-Imidazoleacrylic acid), synthesized in the epidermis, functions as a primary absorber of ultraviolet (UV) radiation in mammalian skin.
T19931 Gentisein NSC 329491,NSC329491,NSC-329491 Serotonin Transporter
Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7 µM[1][2].
T13693 Fibrin Others
Fibrin, the primary constituent of blood clots, is an insoluble protein essential for coagulation. Isolated from bovine blood, this protein is notably synthesized in response to bleeding.
T2977 Vanillin acetate Acetovanillin,Acetylvanillin,4-Formyl-2-methoxyphenyl acetate,4-Acetoxy-3-methoxybenzaldehyde Others
Acetylvanillin is a derivative of Vanillin, the primary component found in vanilla bean extract.
T4S0779 D-tetrahydropalmatine Others , Dopamine Receptor
D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor, it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isolate rat primary hepatocytes, and attenuate the viability re...
T22300 Creatine monohydrate Methylguanidoacetic acid monohydrate Others , Endogenous Metabolite
Creatine monohydrate (Methylguanidoacetic acid monohydrate) is a key player in the phosphagen energy system, especially in muscle and the brain. Creatine monohydrate is the primary source of ATP during high-intensity, sh...
T3090 Abietic Acid Rosin Acid,L-Abietic acid,Sylvic acid,Abietate MMP , Lipoxygenase , Antibacterial , PPAR
Abietic Acid (Sylvic acid) is the primary component of resin acid isolated from rosin.
T3670 Forsythiaside A Forsythiaside,Forsythoside A Others
Forsythiaside A (Forsythiaside) has antimicrobial, anticomplementary, anti-inflammatory and antiendotoxin activities. Forsythiaside A inhibits Infected cells was confirmed by infecting primary chicken embryo kidney cells...
TN1933 Mitraphylline IL Receptor , TNF , NF-κB
Mitraphylline has antiproliferative effects on human glioma and neuroblastoma cell lines. It also has anti-inflammatory activity, it inhibits lipopolysaccharide-mediated activation of primary human neutrophils.
T4333 Quinine dihydrochloride Quinine bimuriate Others
Quinine dihydrochloride (Quinine bimuriate) is a primary alkaloid of various species of Cinchona (Rubiaceae). It is also an antimalarial and muscle relaxant (skeletal).
T2926 Schizandrin A P450 , Virus Protease , Autophagy
Schisandrin A, a primary active component extracted from the traditional Eastern medicine Schisandra chinensis, inhibits CYP3A activity, with an IC50 of 6.60 μM and a Ki of 5.83 μM.
T0856 Dehydroisoandrosterone 3-acetate Dehydroepiandrosterone 3-acetate,Dehydroepiandrosterone acetate,Prasterone acetate,DHEA acetate,androstenolone acetate Androgen Receptor
Dehydroisoandrosterone 3-acetate (Prasterone acetate) is a primary C19 steroid generated by the adrenal cortex.
T3761 1-Octacosanol n-Octacosanol,Montanyl alcohol,Cluytyl alcohol,Octacosanol,Octacosyl alcohol,Octanosol Others
1-Octacosanol (Octanosol) is a straight-chain aliphatic 28-carbon primary fatty alcohol that is used as a nutritional supplement. It is reported to possess cholesterol-lowering effects, antiaggregatory properties, cytopr...
T6395 Astragaloside A Astragalin A,Astramembrannin I Calcium Channel
Astragaloside A (Astramembrannin I) (Astragaloside IV) is the primary pure saponin isolated from Astragalus membranaceus, which has been widely used for the therapy of cardiovascular diseases.
T20091 Stearamide Stearic acid amide,NSC 66462,NSC66462,NSC-66462
Stearamide(Stearic acid amide) is a primary fatty acid amide that is cytotoxic and fish toxic and can be used to increase the properties of nanoparticles.
T2893 Muscone 3-Methylcyclopentadecanone,Methylexaltone MMP , TNF , NF-κB , NOD-like Receptor (NLR) , P-gp , Interleukin
Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.
TN1480 Cephaeline Virus Protease , Influenza Virus , HIF
Cephaeline was highly active against protected primary CLL cells (relative IC50's 35nM ) and acted by repressing HIF-1α± and disturbing intracellular redox homeostasis.
T6S0920 2"-O-Galloylhyperin 2''-O-Galloylhyperin,Q-100605,FT-0689359 Others
2"-O-Galloylhyperin (FT-0689359) found in Pyrola. It increases ruminal fiber fermentability by formed wall-bound lignin in primary maize cell walls.
T4884 Alpha-D-glucose α-D-Glucose,alpha-Glucose,α-Dextrose Others , Endogenous Metabolite
alpha-D-glucose (α-Dextrose) is a primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutri...
T2963 Cholic Acid Cholanic acid,Cholate,Colalin Endogenous Metabolite
Cholic Acid (Cholate) is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. Cholic acid facilitates fat absorption and cholesterol excretion.
T11060 DMAPT Dimethylamino Parthenolide NF-κB
DMAPT (Dimethylamino Parthenolide) is a water-soluble analogue of Parthenolide (PTL). It is an orally active NF-κB inhibitor with an LD50 of 1.7 μM on primary acute myeloid leukemia cells.
T13589 Caesappanin C Others
Caesappanin C, extracted from the heartwood of Indonesian Caesalpinia sappan L., shows strong proliferation stimulating activity against the primary osteoblastic cells in vitro.
TN6891 1-Hexanol hexan-1-ol Others
1-Hexanol (hexan-1-ol) is a natural product.1-Hexanol, a primary alcohol, is a surfactant that can be employed in industrial processes to enhance interfacial properties[1]. 1-Hexanol uncouples mitochondrial respiration b...
T3674 Hydroxysafflor yellow A HSYA,Safflomin A TGF-beta/Smad
Hydroxysafflor yellow A (Safflomin A) inhibited adipogenesis by increasing HSL promoter activities. Hydroxysafflor yellow A can effectively protect the liver from long-term alcohol injury by enhancing antioxidant capacit...
T3768 Epifriedelanol Epifriedelinol Others
Epifriedelanol (Epifriedelinol) suppresses adriamycin-induced cellular senescence, replicative senescence in human fibroblasts (HDFs) and HUVECs. Because of Epifriedelanol can reduce cellular senescence in human primary ...
T5S1708 Dendrobine Others , Influenza Virus
1. Dendrobine has a slight but demonstrable analgesic and antipyretic action. 2. Dendrobine produces moderate hyperglycemia, diminishes cardiac activity in large doses, lowers the blood pressure. 3. Dendrobine on the ele...
T0887 D-Glucose Dextrose,Glucopyranose,Grape sugar,D(+)-Glucose Endogenous Metabolite
D-Glucose (Glucopyranose) is a primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient...
T3800 Typhaneoside Aervitrin Others , Autophagy
Typhaneoside (Aervitrin) is a flavonoid glycoside plant extract with potential ability to treat primary dysmenorrhea through the Shaofu Zhuyu decoction.
T2598 Thymopentin TP5 Estrogen/progestogen Receptor , Endogenous Metabolite
Synthetic pentapeptide corresponding to the amino acids 32-36 of thymopoietin and exhibiting the full biological activity of the natural hormone. Thymopentin (TP5) is an immunomodulator which has been studied for possibl...
T37886 1-Heptadecanol Antibacterial
1-Heptadecanol is a long-chain primary alcohol with antibacterial activity from Solena amplexicaulis leaves[1]. [1]. Soumendranath Chatterjee, et al. Antibacterial Activity of Long-Chain Primary Alcohols from Solena ampl...
T0076 Paliperidone 9-hydroxyrisperidone Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Histamine Receptor
Paliperidone (9-hydroxyrisperidone)(Invega) is used as an atypical antipsychotic. It applies to the acute and maintenance treatment of schizophrenia. Chemically, paliperidone is the primary active metabolite of the older...
TCS2070 Homogentisic acid 2,5-dihydroxyphenylacetic acid,Homogentisinic Acid,Melanic acid Antioxidant , Endogenous Metabolite
1. Homogentisic acid (2,5-dihydroxyphenylacetic acid) shows interesting antioxidant and antiradical activities, and protective effect against thermal-cholesterol degradation, comparable to those of well known antioxidant...
T4843 2,2-Dihydroxyacetic acid Formylformic acid,Glyoxylic acid monohydrate Others , Endogenous Metabolite
2,2-Dihydroxyacetic acid (Formylformic acid) is an intermediate in the glyoxalate cycle, which enables certain organisms to convert fatty acids to carbohydrates.2,2-Dihydroxyacetic acid has been found to be associated wi...
T5234 Glycoursodeoxycholic acid Ursodeoxycholylglycine,GUDCA Others , Endogenous Metabolite
Glycoursodeoxycholic acid (Ursodeoxycholylglycine) is an acyl glycine and a bile acid-glycine conjugate. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of the colonic enviro...
T5S2129 Sciadopitysin TNF , NF-κB
Sciadopitysin may prevent the development of diabetic osteopathy, it exerts its therapeutic effects via upregulation of mitochondrial biogenesis.Sciadopitysin shows protective effects on antimycin A-induced toxicity in o...
T5S2283 Sesamolin p38 MAPK , Caspase , JNK
1. Sesamolin and Sesamin has neuroprotective effect. 2. Sesamolin protects microglia against H2O2-induced cell injury, by inhibiting of p38 MAPK and caspase-3 activation and ROS production. 3. Sesamolin and Sesamin can s...
T19281L Dihydroxyacetone phosphate hemimagnesium salt hydrate Dihydroxyacetone phosphate hemimagnesium salt hydrate(57-04-5 free base) Others
Dihydroxyacetone phosphate hemimagnesium salt hydrate is a member of the class of glycerone phosphates that consists of glycerone bearing a single phospho substituent. It has a role as a human metabolite, a Saccharomyces...
T2532 Tauroursodeoxycholate Taurolite,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA Apoptosis , ERK , P450 , Caspase , Endogenous Metabolite
Tauroursodeoxycholate (UR 906), also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. Tauroursodeoxycholate is the more hydrophilic form of ursode...
T5287 N-Acetyl-L-aspartic acid AC-ASP-OH,N-Acetylaspartic acid Others , Endogenous Metabolite
N-Acetyl-L-aspartic acid (AC-ASP-OH) is a derivative of aspartic acid. It is the second most concentrated molecule in the brain after the amino acid glutamate. It is synthesized in neurons from the amino acid aspartate a...
T2163 Dihydrocapsaicin CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide Others , TRP/TRPV Channel
Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsaicin, dihydrocapsaicin is an...
T37984 D-Fructose-1,6-bisphosphate sodium salt hydrate Others
D-Fructose-1,6-bisphosphate sodium salt hydrate is the intermediate in carbohydrate metabolism, including glycolysis and gluconeogenesis. During glycolysis, it is produced by phosphorylation of fructose-6-phosphate by ph...
T13520 6-Hydroxymelatonin Others
6-Hydroxymelatonin is a primary metabolic of Melatonin, which is metabolized by CYP 1A2.
T19623 α-Muricholic acid AChR
α-Muricholic acid is the most abundant primary bile acid in rodents.
TN6536 Decuroside I
Decuroside I shows weak inhibiting activity against the primary and secondary wave aggregation of human platelet.
TN1581 Dihydroguaiaretic acid COX , DNA/RNA Synthesis
Dihydroguaiaretic acid has antioxidative activity, can significantly protect primary cultured neuronal cells against glutamate-induced oxidative stress.
T19186 Aldosterone Others
Aldosterone is the primary mineralocorticoid. Aldosterone is synthesized and secreted in response to renin-angiotensin system activation or high dietary potassium by the zona glomerulosa of the adrenal cortex.
TN1751 Hydroxycitric acid ERK , p38 MAPK , Fatty Acid Synthase
(-)-Hydroxycitric acid (HCA) can inhibit fat synthesis and reduces food intake, the primary mechanism of action of HCA appears to be related to its ability to act as a competitive inhibitor of the enzyme ATP-citrate lyas...
T40741 Dracorhodin
Dracorhodin, the primary constituent found in the sanguis draconis extract, is a flavylium compound classified within the anthocyanin family. Notably, dracorhodin possesses the ability to elicit vasodilation.
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Natural Products

Glycolithocholic acid
T31964
Synonym: Lithocholic acid glycine conjugate,Lithocholylglycine
Target: Others
Meisoindigo
T1882
Synonym: N-Methylisoindigotin,Methylisoindigotin,Natura-α,Dian III
Target: Apoptosis
Urocanic acid
T4759
Synonym: 4-Imidazoleacrylic acid
Target: Others, Endogenous Metabolite
Gentisein
T19931
Synonym: NSC 329491,NSC329491,NSC-329491
Target: Serotonin Transporter
Fibrin
T13693
Synonym:
Target: Others
Vanillin acetate
T2977
Synonym: Acetovanillin,Acetylvanillin,4-Formyl-2-methoxyphenyl acetate,4-Acetoxy-3-methoxybenzaldehyde
Target: Others
D-tetrahydropalmatine
T4S0779
Synonym:
Target: Others, Dopamine Receptor
Creatine monohydrate
T22300
Synonym: Methylguanidoacetic acid monohydrate
Target: Others, Endogenous Metabolite
Abietic Acid
T3090
Synonym: Rosin Acid,L-Abietic acid,Sylvic acid,Abietate
Target: MMP, Lipoxygenase, Antibacterial, PPAR
Forsythiaside A
T3670
Synonym: Forsythiaside,Forsythoside A
Target: Others
Mitraphylline
TN1933
Synonym:
Target: IL Receptor, TNF, NF-κB
Quinine dihydrochloride
T4333
Synonym: Quinine bimuriate
Target: Others
Schizandrin A
T2926
Synonym:
Target: P450, Virus Protease, Autophagy
Dehydroisoandrosterone 3-acetate
T0856
Synonym: Dehydroepiandrosterone 3-acetate,Dehydroepiandrosterone acetate,Prasterone acetate,DHEA acetate,androstenolone acetate
Target: Androgen Receptor
1-Octacosanol
T3761
Synonym: n-Octacosanol,Montanyl alcohol,Cluytyl alcohol,Octacosanol,Octacosyl alcohol,Octanosol
Target: Others
Astragaloside A
T6395
Synonym: Astragalin A,Astramembrannin I
Target: Calcium Channel
Stearamide
T20091
Synonym: Stearic acid amide,NSC 66462,NSC66462,NSC-66462
Target:
Muscone
T2893
Synonym: 3-Methylcyclopentadecanone,Methylexaltone
Target: MMP, TNF, NF-κB, NOD-like Receptor (NLR), P-gp, Interleukin
Cephaeline
TN1480
Synonym:
Target: Virus Protease, Influenza Virus, HIF
2"-O-Galloylhyperin
T6S0920
Synonym: 2''-O-Galloylhyperin,Q-100605,FT-0689359
Target: Others
alpha-D-glucose
T4884
Synonym: α-D-Glucose,alpha-Glucose,α-Dextrose
Target: Others, Endogenous Metabolite
Cholic Acid
T2963
Synonym: Cholanic acid,Cholate,Colalin
Target: Endogenous Metabolite
DMAPT
T11060
Synonym: Dimethylamino Parthenolide
Target: NF-κB
Caesappanin C
T13589
Synonym:
Target: Others
1-Hexanol
TN6891
Synonym: hexan-1-ol
Target: Others
Hydroxysafflor yellow A
T3674
Synonym: HSYA,Safflomin A
Target: TGF-beta/Smad
Epifriedelanol
T3768
Synonym: Epifriedelinol
Target: Others
Dendrobine
T5S1708
Synonym:
Target: Others, Influenza Virus
D-Glucose
T0887
Synonym: Dextrose,Glucopyranose,Grape sugar,D(+)-Glucose
Target: Endogenous Metabolite
Typhaneoside
T3800
Synonym: Aervitrin
Target: Others, Autophagy
Thymopentin
T2598
Synonym: TP5
Target: Estrogen/progestogen Receptor, Endogenous Metabolite
1-Heptadecanol
T37886
Synonym:
Target: Antibacterial
Paliperidone
T0076
Synonym: 9-hydroxyrisperidone
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Histamine Receptor
Homogentisic acid
TCS2070
Synonym: 2,5-dihydroxyphenylacetic acid,Homogentisinic Acid,Melanic acid
Target: Antioxidant, Endogenous Metabolite
2,2-Dihydroxyacetic acid
T4843
Synonym: Formylformic acid,Glyoxylic acid monohydrate
Target: Others, Endogenous Metabolite
Glycoursodeoxycholic acid
T5234
Synonym: Ursodeoxycholylglycine,GUDCA
Target: Others, Endogenous Metabolite
Sciadopitysin
T5S2129
Synonym:
Target: TNF, NF-κB
Sesamolin
T5S2283
Synonym:
Target: p38 MAPK, Caspase, JNK
Dihydroxyacetone phosphate hemimagnesium salt hydrate
T19281L
Synonym: Dihydroxyacetone phosphate hemimagnesium salt hydrate(57-04-5 free base)
Target: Others
Tauroursodeoxycholate
T2532
Synonym: Taurolite,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA
Target: Apoptosis, ERK, P450, Caspase, Endogenous Metabolite
N-Acetyl-L-aspartic acid
T5287
Synonym: AC-ASP-OH,N-Acetylaspartic acid
Target: Others, Endogenous Metabolite
Dihydrocapsaicin
T2163
Synonym: CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide
Target: Others, TRP/TRPV Channel
D-Fructose-1,6-bisphosphate sodium salt hydrate
T37984
Synonym:
Target: Others
6-Hydroxymelatonin
T13520
Synonym:
Target: Others
α-Muricholic acid
T19623
Synonym:
Target: AChR
Decuroside I
TN6536
Synonym:
Target:
Dihydroguaiaretic acid
TN1581
Synonym:
Target: COX, DNA/RNA Synthesis
Aldosterone
T19186
Synonym:
Target: Others
Hydroxycitric acid
TN1751
Synonym:
Target: ERK, p38 MAPK, Fatty Acid Synthase
Dracorhodin
T40741
Synonym:
Target:

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPK-00300 CD5 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated Mouse HEK293
CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell...
TMPK-00006 CD24 Protein (Primary Amine Labeling), Human, Recombinant (mFc), Biotinylated Human HEK293
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo...
TMPK-00522 PSMA Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated Cynomolgus HEK293
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate...
TMPK-00100 CD7 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated Mouse HEK293
CD7, also known as Leu-9, is an approximately 40 kDa glycosylated and palmitoylated transmembrane protein in the immunoglobulin superfamily.CD7 is expressed on T cells, NK cells , myeloid progenitor cells, and CD19 B pro...
TMPK-01245 GDF-15 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated Mouse HEK293
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPK-00096 FGF-10 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated Human E. coli
Fibroblast growth factor 10 (FGF10) regulates multiple stages of structural lung morphogenesis, cellular differentiation, and the response to injury. As a driver of lung airway branching morphogenesis, FGF10 signaling de...
TMPK-00675 CD24 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated Cynomolgus HEK293
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo...
TMPK-00341 ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated Human HEK293
Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression pr...
TMPK-00076 IL-18 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated Human E. coli
Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop...
TMPK-00502 PADI4 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated Cynomolgus E. coli
Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide anti...
TMPK-00582 MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated Rat E. coli
The dysregulation of complement cascade leads to unsolicited cytokine storm, inflammation, deterioration of alveolar lining cells, culminating in acquired respiratory destructive syndrome (ARDS). Similar pathogenesis is ...
TMPK-01238 PADI4 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated Human E. coli
Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide anti...
TMPK-00406 TLR3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated Human HEK293
TLR3 is expressed in the central nervous system (CNS), where it is required to control HSV-1, which spreads from the epithelium to the CNS via cranial nerves. TLR3 is also expressed in epithelial and dendritic cells, whi...
TMPK-01210 DLL3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated Human HEK293
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differe...
TMPK-00005 CD24 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated Human HEK293
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential fo...
TMPK-01224 CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated Mouse HEK293
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00410 AXL Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated Human HEK293
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre...
TMPK-00104 HMGB1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated Human HEK293
High-mobility group box 1 (HMGB1) is a ubiquitous nuclear protein that promotes inflammation when released extracellularly after cellular activation, stress, damage or death. HMGB1 operates as one of the most intriguing ...
TMPK-00482 TSLP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated Cynomolgus HEK293
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of ...
TMPK-00371 PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated Mouse HEK293
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate...
TMPK-00937 CKAP4 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated Human E. coli
Cytoskeleton-associated protein 4 (CKAP4) is located in the rough endoplasmic reticulum (ER) and plays an important role in stabilizing the structure of ER. Meanwhile, CKAP4 is also found to act as an activated receptor ...
TMPK-00204 FGL1 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated Human HEK293
Fibrinogen-like protein 1 (FGL-1) is a protein that is structurally related to fibrinogen. In humans, FLG-1 is encoded by the FGL1 gene.Fibrinogen-like protein 1 is a member of the fibrinogen family of proteins, which al...
TMPK-01136 CD3 epsilon/CD3e Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated Cynomolgus HEK293
CD3E, is a single-pass type I membrane protein.CD3 (cluster of differentiation 3) T cell co-receptor helps to activate both the cytotoxic T cell (CD8 naive T cells) and also T helper cells (CD4 naive T cells). It consist...
TMPK-00080 CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated Human HEK293
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a cytokine that binds to CD27. Plays a role in T-cell activa...
TMPK-00142 APRIL/TNFSF13 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated Human HEK293
The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily re...
TMPK-00181 PD-1 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated Mouse HEK293
Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the ...
TMPK-01026 MSLN/Mesothelin Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated Mouse HEK293
Mesothelin, also known as MSLN, is a protein that in humans is encoded by the MSLN gene.Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached ...
TMPK-00231 Siglec-15 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated Mouse HEK293
Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, ...
TMPK-00492 IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated Cynomolgus HEK293
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggestin...
TMPK-00664 GDF-15 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated Cynomolgus HEK293
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPK-00198 GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated Human HEK293
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPK-00619 FcRH5/FcRL5 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated Human HEK293
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE),...
TMPK-01397 MSLN/Mesothelin Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated Cynomolgus HEK293
Mesothelin, also known as MSLN, is a protein that in humans is encoded by the MSLN gene.Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached ...
TMPK-00720 Siglec-5 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated Human HEK293
Group B Streptococcus (GBS) causes invasive infections in human newborns. the GBS β-protein attenuates innate immune responses by binding to sialic acid-binding immunoglobulin-like lectin 5 (Siglec-5), an inhibitory rece...
TMPK-00615 NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated Human HEK293
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expresse...
TMPK-00169 OX40/TNFRSF4 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated Human HEK293
Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; i...
TMPK-00662 PD-L1 Protein (Primary Amine Labeling), Cynomolgus/Rhesus macaque, Recombinant (His), Biotinylated Cynomolgus,Rhesus macaque HEK293
B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor progr...
TMPK-00197 GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (H202D, hFc), Biotinylated Human HEK293
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPK-00154 CD40 Ligand Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated Human HEK293
CD40 ligand or CD40L, also called CD154,  is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), w...
TMPK-00763 Apolipoprotein E/APOE3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated Human HEK293
Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury...
TMPK-00081 FGF-7/KGF Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated Human E. coli
The expression patterns of mRNAs encoding Fibroblast Growth Factor-7 (FGF-7) and its high affinity receptor suggested that FGF-7 signaling may play a role in regulating ureteric bud growth.t Results of these studies demo...
TMPJ-00379 AOC3 Protein, Human, Recombinant (hFc) Human Human Cells
Membrane primary amine oxidase(AOC3), also known as vascular adhesion protein (VAP-1) and HPAO, this protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family. VAP-1 is a type 1 membrane-bound glycop...
TMPK-00951 CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated Human HEK293
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00054 GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated Human HEK293
Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due...
TMPK-00259 Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated Human HEK293
Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, including cell proliferation, cell survival, and cell differen...
TMPK-00987 IL-2 R gamma/CD132 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated Cynomolgus HEK293
The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232...
TMPK-00321 IL-2 R beta/CD122 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated Cynomolgus HEK293
IL-2 R beta is a member of the cytokine receptor superfamily. Human IL-2 R beta cDNA encodes a 551 amino acid residue precursor Type I membrane protein with a 26 residue signal peptide, a 214 residue extracellular region...
TMPJ-00380 AOC3 Protein, Human, Recombinant (His) Human Human Cells
Vascular adhesion protein-1(VAP-1) is a copper amine oxidase with a topaquinone cofactor.VAP-1 is a type II integral membrane protein, but a soluble form of the enzyme is present in human serum, and its level increases i...
TMPJ-00700 GADD45B Protein, Human, Recombinant (His) Human E. coli
Growth Arrest and DNA Damage-Inducible Protein GADD45 β (GADD45B) is a member of the GADD45 family. GADD45B has been shown to interact with MAP3K4, ASK1, MAP2K7, and GADD45GIP1. GADD45B is involved in the regulation of g...
TMPY-02335 OSMR Protein, Mouse, Recombinant (His) Mouse HEK293
Oncostatin-M specific receptor subunit beta also known as the oncostatin M receptor (OSMR) and Interleukin-31 receptor subunit beta (IL-31RB), is one of the receptor proteins for oncostatin M. OSMR is a member of the typ...
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CD5 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
TMPK-00300
Species: Mouse
Expression System: HEK293
CD24 Protein (Primary Amine Labeling), Human, Recombinant (mFc), Biotinylated
TMPK-00006
Species: Human
Expression System: HEK293
PSMA Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
TMPK-00522
Species: Cynomolgus
Expression System: HEK293
CD7 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated
TMPK-00100
Species: Mouse
Expression System: HEK293
GDF-15 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated
TMPK-01245
Species: Mouse
Expression System: HEK293
FGF-10 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated
TMPK-00096
Species: Human
Expression System: E. coli
CD24 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated
TMPK-00675
Species: Cynomolgus
Expression System: HEK293
ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TMPK-00341
Species: Human
Expression System: HEK293
IL-18 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated
TMPK-00076
Species: Human
Expression System: E. coli
PADI4 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
TMPK-00502
Species: Cynomolgus
Expression System: E. coli
MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated
TMPK-00582
Species: Rat
Expression System: E. coli
PADI4 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TMPK-01238
Species: Human
Expression System: E. coli
TLR3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TMPK-00406
Species: Human
Expression System: HEK293
DLL3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TMPK-01210
Species: Human
Expression System: HEK293
CD24 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
TMPK-00005
Species: Human
Expression System: HEK293
CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
TMPK-01224
Species: Mouse
Expression System: HEK293
AXL Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
TMPK-00410
Species: Human
Expression System: HEK293
HMGB1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TMPK-00104
Species: Human
Expression System: HEK293
TSLP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
TMPK-00482
Species: Cynomolgus
Expression System: HEK293
PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
TMPK-00371
Species: Mouse
Expression System: HEK293
CKAP4 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TMPK-00937
Species: Human
Expression System: E. coli
FGL1 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
TMPK-00204
Species: Human
Expression System: HEK293
CD3 epsilon/CD3e Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
TMPK-01136
Species: Cynomolgus
Expression System: HEK293
CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TMPK-00080
Species: Human
Expression System: HEK293
APRIL/TNFSF13 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
TMPK-00142
Species: Human
Expression System: HEK293
PD-1 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated
TMPK-00181
Species: Mouse
Expression System: HEK293
MSLN/Mesothelin Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
TMPK-01026
Species: Mouse
Expression System: HEK293
Siglec-15 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
TMPK-00231
Species: Mouse
Expression System: HEK293
IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
TMPK-00492
Species: Cynomolgus
Expression System: HEK293
GDF-15 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated
TMPK-00664
Species: Cynomolgus
Expression System: HEK293
GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
TMPK-00198
Species: Human
Expression System: HEK293
FcRH5/FcRL5 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TMPK-00619
Species: Human
Expression System: HEK293
MSLN/Mesothelin Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
TMPK-01397
Species: Cynomolgus
Expression System: HEK293
Siglec-5 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
TMPK-00720
Species: Human
Expression System: HEK293
NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TMPK-00615
Species: Human
Expression System: HEK293
OX40/TNFRSF4 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
TMPK-00169
Species: Human
Expression System: HEK293
PD-L1 Protein (Primary Amine Labeling), Cynomolgus/Rhesus macaque, Recombinant (His), Biotinylated
TMPK-00662
Species: Cynomolgus,Rhesus macaque
Expression System: HEK293
GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (H202D, hFc), Biotinylated
TMPK-00197
Species: Human
Expression System: HEK293
CD40 Ligand Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
TMPK-00154
Species: Human
Expression System: HEK293
Apolipoprotein E/APOE3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TMPK-00763
Species: Human
Expression System: HEK293
FGF-7/KGF Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TMPK-00081
Species: Human
Expression System: E. coli
AOC3 Protein, Human, Recombinant (hFc)
TMPJ-00379
Species: Human
Expression System: Human Cells
CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TMPK-00951
Species: Human
Expression System: HEK293
GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
TMPK-00054
Species: Human
Expression System: HEK293
Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TMPK-00259
Species: Human
Expression System: HEK293
IL-2 R gamma/CD132 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
TMPK-00987
Species: Cynomolgus
Expression System: HEK293
IL-2 R beta/CD122 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
TMPK-00321
Species: Cynomolgus
Expression System: HEK293
AOC3 Protein, Human, Recombinant (His)
TMPJ-00380
Species: Human
Expression System: Human Cells
GADD45B Protein, Human, Recombinant (His)
TMPJ-00700
Species: Human
Expression System: E. coli
OSMR Protein, Mouse, Recombinant (His)
TMPY-02335
Species: Mouse
Expression System: HEK293
Cat No. Product Name
L2500 Human Endogenous Metabolite Library

508 compounds
A collection of 508 selected human endogenous metabolites for high throughput and high content screening.
L2196 Anti-Ovarian Cancer Compound Library

1888 compounds
A unique collection of 1888 compounds with anti-ovarian cancer therapeutic activity, can be used for anti-ovarian cancer drug discovery and pharmacological study;
TargetMol