Search Result

Search Results for " pool "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T6357	(S)-crizotinib	ent-crizotinib	Apoptosis , DNA/RNA Synthesis , MTH1
	(S)-crizotinib (ent-crizotinib) （IC50 of 72 nM）, an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.		Apoptosis , DNA/RNA Synthesis , MTH1
T60217	TAS1553		Others
	TAS1553 is a highly effective, orally bioavailable protein-protein interaction (PPI) inhibitor with an IC50 value of 0.0396 μM. It effectively hinders DNA replication and diminishes the intracellular dATP pool. Moreover,...		Others
TP1687L	CEF20 acetate(153045-21-7 free base)		Others
	CEF20 acetate is a CEF control peptide pool, is an HLA-A*0201-restricted epitope from cytomegalovirus pp65 (495-503).		Others
T8860	DSRM-3716		Androgen Receptor
	Isoquinoline, 5-iodo- (9CI) is a potent and selective inhibitor of SARM1(IC50 = 75 nM) by preventing axonal degeneration and by allowing functional recovery of a metastable pool of damaged, but viable, axons.		Androgen Receptor
T20870	IR-820	IR 820,IR820,New Indocyanine Green
	IR-820 (New Indocyanine Green) is a near-infrared dye with better stability, good color rendering, and excellent fluorescence penetration. IR-820 is an infrared blood pool contrast agent used to detect and quantify disea...
T83971L	LCC-12 FA		Antiviral , Antibacterial
	LCC-12 FA is a dimer composed of metformin that induces a decrease in the NAD(H) pool by targeting mitochondrial copper(ii).LCC-12 FA reduces inflammation in mouse models of bacterial and viral infections and may be used...		Antiviral , Antibacterial
T6301	Tosedostat	CHR-2797	Aminopeptidase , AChR
	Tosedostat (CHR-2797) is an orally bioavailable inhibitor of the M1 family of aminopeptidases with potential antineoplastic activity. Tosedostat is converted intracellularly into a poorly membrane-permeable active metabo...		Aminopeptidase , AChR
T3157	COH29	RNR Inhibitor COH29	DNA/RNA Synthesis
	COH29 (RNR Inhibitor COH29) is an orally available, aromatically substituted thiazole and inhibitor of the human ribonucleotide reductase (RNR), with potential antineoplastic activity. Upon oral administration, the RNR i...		DNA/RNA Synthesis
T34324	Ribulose, L-	L-Adonose,L-Ribulose,L-Erythro-pentulose,L-erythro-2-Pentulose
	Ribulose is an important metabolite in pentose interconversions. Ribulose is useful for analyzing L-ribose isomerase, engineering yeast for xylose metabolism, interesting chiral pool compound.
TP1687	CEF20
	CEF20, a CEF control peptide pool, is an HLA-A*0201-restricted epitope from cytomegalovirus pp65 (495-503).
T35546	Yhhu 3792
	Notch signaling pathway activator; enhances the self-renewal capability of neural stem cells (NSCs) via Notch signaling pathway activation in vitro and in vivo. Promotes the expression of Notch target genes, Hes3 and Hes...
T38081	Tunicamycin 14:1 Mixture
	Tunicamycin 14:1 is a mixture of tunicamycin structural isomers that contain a 14-carbon N-acyl chain with variable branching patterns. The N-acyl chain incorporated into tunicamycins, like tunicamycin 14:1, is derived f...
T15378	Gemcitabine elaidate	Gemcitabine 5'-elaidate,Gemcitabine (elaidate),CO-101,CP-4126	Apoptosis , Nucleoside Antimetabolite/Analog , Autophagy
	Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracel...		Apoptosis , Nucleoside Antimetabolite/Analog , Autophagy
T38083	Tunicamycin 17:1 Mixture
	Tunicamycin 17:1 is a mixture of tunicamycin structural isomers that contain a 17-carbon N-acyl chain with variable branching patterns. The N-acyl chain incorporated into tunicamycins, like tunicamycin 17:1, is derived f...
T35552	Ganglioside GD3 Mixture (sodium salt)
	Ganglioside GD3 is synthesized by the addition of two sialic acid residues to lactosylceramide and can serve as a precursor to the formation of more complex gangliosides by the action of glycosyl- and sialyltransferases....
T38082	Tunicamycin 15:1 Mixture
	Tunicamycin 15:1 is a mixture of tunicamycin structural isomers that contain a 15-carbon N-acyl chain with variable branching patterns. The N-acyl chain incorporated into tunicamycins, like tunicamycin 15:1, is derived f...
T61930	Yhhu-3792
	Yhhu-3792 activates Notch signaling pathway and promotes the expression of Hes3 and Hes5. Yhhu-3792 enhanced the self-renewal ability of neural stem cells (NSCs), expanded the NSC pool and promoted endogenous neurogenesi...

Compounds

(S)-crizotinib

T6357

Synonym: ent-crizotinib

Target: Apoptosis, DNA/RNA Synthesis, MTH1

CEF20 acetate(153045-21-7 free base)

Target: Androgen Receptor

IR-820

T20870

Synonym: IR 820,IR820,New Indocyanine Green

Target: Antiviral, Antibacterial

Tosedostat

T6301

Synonym: CHR-2797

Target: Aminopeptidase, AChR

COH29

T3157

Synonym: RNR Inhibitor COH29

Target: DNA/RNA Synthesis

Ribulose, L-

T34324

Synonym: L-Adonose,L-Ribulose,L-Erythro-pentulose,L-erythro-2-Pentulose

Tunicamycin 14:1 Mixture

Synonym: Gemcitabine 5'-elaidate,Gemcitabine (elaidate),CO-101,CP-4126

Target: Apoptosis, Nucleoside Antimetabolite/Analog, Autophagy

Tunicamycin 17:1 Mixture

T38083

Synonym:

Target:

Ganglioside GD3 Mixture (sodium salt)

T35552

Synonym:

Target:

Tunicamycin 15:1 Mixture

Cat No.	Product Name	Synonyms	Targets
T19121	3-Hydroxyvaleric acid		Others
	3-Hydroxyvaleric acid is anaplerotic, meaning it can refill the pool of TCA cycle intermediates.		Others
T7995	α-Angelica lactone	Alpha-Angelica Lactone	Others , GST
	α-Angelica lactone has cardiotonic activity, may exert their effects by providing an increased contraction-dependent calcium pool to be released upon systolic depolarization.		Others , GST
T5S1097	Neferine	(R)-1,2-Dimethoxyaporphine,(-)-Neferine	Apoptosis , NF-κB , Autophagy
	1. Neferine ((-)-Neferine) has anti-tumor activities , Metabolic activation mediated by CYP3A4 and GSH depletion enhanced Neferine-induced cytotoxicity. 2. Neferine can be helpful to increase the efficacy of DOX and to a...		Apoptosis , NF-κB , Autophagy
TN3557	Cabraleadiol		ATPase , Antifection
	Cabraleadiol displays antimycobacterial activity against Mycobacterium tuberculosis, it also is weakly cytotoxic to a breast cancer (BC) cell line. Cabraleadiol inhibits photosystem II (PS II) and induces the appearance ...		ATPase , Antifection

Natural Products

3-Hydroxyvaleric acid

Synonym: Alpha-Angelica Lactone

Target: Others, GST

Neferine

T5S1097

Synonym: (R)-1,2-Dimethoxyaporphine,(-)-Neferine

Target: Apoptosis, NF-κB, Autophagy

Cabraleadiol

TN3557

Synonym:

Target: ATPase, Antifection

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-00304	SV2A Protein, Bovine, Recombinant (His & Myc)	Bovine	HEK293
	Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of s...
TMPK-00540	Serpin F2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Large-pool solvent/detergent (SD) plasma for transfusion exhibits reduced alpha 2-antiplasmin (alpha2-AP; SERPINF2) functional activity. The reason for the loss of alpha2-AP has not been described and could be due to the...
TMPK-00015	Cpn10/HSPE1 Protein, Human/Mouse/Goat, Recombinant (His & Avi)	Human,Mouse,Goat	E. coli
	Cpn10/HSPE, a 10-kDa heat shock protein, is a novel interacting partner of NPAT. A pool of Cpn10 is colocalized with NPAT foci during G1 and S phases in nuclei.Cpn10 is important for S phase progression and cell prolifer...
TMPK-00016	Cpn10/HSPE1 Protein, Human/Mouse/Goat, Recombinant (His & Avi), Biotinylated	Human,Mouse,Goat	E. coli
	Cpn10/HSPE, a 10-kDa heat shock protein, is a novel interacting partner of NPAT. A pool of Cpn10 is colocalized with NPAT foci during G1 and S phases in nuclei.Cpn10 is important for S phase progression and cell prolifer...
TMPH-03415	Rift valley fever virus (RVFV) (strain ZH-548 M12) Non-structural protein S (His & Myc)	RVFV	E. coli
	Plays a role in the escape of host innate immune response by promoting the degradation of host EIF2AK2/PKR and inhibiting host transcription. Cytoplasmic NSs interacts with host FBXW11 to degrade PKR whereas nuclear pool...
TMPH-00568	8-oxo-dGTP diphosphatase Protein, E. coli, Recombinant (His & SUMO)	E. coli	E. coli
	Specifically hydrolyzes both 8-oxo-deoxyguanosine triphosphate (8-oxo-dGTP) and 8-oxo-guanosine triphosphate (8-oxo-GTP) to the related monophosphates, thereby cleaning up the nucleotide pools and preventing misincorpora...
TMPY-04480	UMP-CMP kinase/CMPK1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), re...
TMPH-00609	DITP/XTP pyrophosphatase Protein, E. coli, Recombinant (His & Myc & SUMO)	E. coli	E. coli
	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinos...
TMPY-03618	BTD Protein, Human, Recombinant (His)	Human	HEK293
	Biotinidase, also known as biotinase and BTD, is a ubiquitous mammalian cell enzyme which expressed at high levels in the liver, serum, and kidney. Its primary function is to cleave biotin from biocytin, preserving the p...
TMPJ-00978	PIP4K2A Protein, Human, Recombinant (His)	Human	Human Cells
	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (PIP4K2A) is a member of the phosphatidylinositol-4-phosphate 5-kinase family. It contains 1 PIPK domain and is expressed ubiquitously, with high levels in the brain...
TMPJ-00411	LEPR Protein, Human, Recombinant (hFc)	Human	Human Cells
	The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta...
TMPJ-00977	LEPR Protein, Mouse, Recombinant (mFc)	Mouse	Human Cells
	The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta...
TMPJ-00975	LEPR Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta...
TMPJ-00976	LEPR Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta...
TMPH-02169	TRBC1 Protein, Human, Recombinant (His)	Human	Yeast
	Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPH-02170	TRBC1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPH-02173	TRBC2 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPH-02172	TRBC2 Protein, Human, Recombinant (His)	Human	Yeast
	Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPH-02167	TRAC Protein, Human, Recombinant (His)	Human	Yeast
	Constant region of T cell receptor (TR) alpha chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize p...
TMPH-02171	TRBC2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPH-02168	TRAC Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Constant region of T cell receptor (TR) alpha chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize p...
TMPY-04755	AK3L1 Protein, Human, Recombinant	Human	Baculovirus-Insect Cells
	Adenylate kinase isoenzyme 4, mitochondrial, also known as ATP-AMP transphosphorylase, Adenylate kinase 3-like, AK4 and AK3L1, is a member theadenylate kinase family. AK4 / AK3L1 is localized to the mitochondrial matri...
TMPY-04469	AK3L1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Adenylate kinase isoenzyme 4, mitochondrial, also known as ATP-AMP transphosphorylase, Adenylate kinase 3-like, AK4 and AK3L1, is a member theadenylate kinase family. AK4 / AK3L1 is localized to the mitochondrial matri...