Search Result

Search Results for " polymerase "

Targets

Antiviral DNA/RNA Synthesis

351

Compounds

Natural Products

115

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T80644	DNA polymerase-IN-1		Antiviral , DNA/RNA Synthesis
	DNA polymerase-IN-1, a DNA polymerase inhibitor, exhibited antiproliferative activity against tumor cells with a half-inhibitory concentration (IC50) of 20.7 μM. DNA polymerase-IN-1 inhibited Taq DNA polymerase with an I...		Antiviral , DNA/RNA Synthesis
T79922	Taq DNA polymerase		DNA/RNA Synthesis
	Taq DNA polymerase is a thermostable enzyme utilized in polymerase chain reactions (PCR) to amplify DNA sequences [1].		DNA/RNA Synthesis
T79926	Poly(A) polymerase		DNA/RNA Synthesis
	Poly(A) polymerase enzymatically adds a polyadenosine tail of 20-200 adenine bases to the 3' end of RNA, a process that involves integrating ATP as AMP. This modification enhances RNA stability and augments mRNA translat...		DNA/RNA Synthesis
T79307	DNA polymerase-IN-2		DNA/RNA Synthesis
	DNA polymerase-IN-2 (Compd 3c), a coumarin derivative, demonstrates inhibitory activity towards Taq DNA polymerase, with an IC50 value of 48.25 μM, and holds potential for application in value-added disease research [1].		DNA/RNA Synthesis
T79308	DNA polymerase-IN-3		DNA/RNA Synthesis
	DNA polymerase-IN-3 (Compd 5b), a coumarin derivative, demonstrates inhibitory activity against Taq DNA polymerase and has potential applications in proliferative disease research [1].		DNA/RNA Synthesis
T82536	DNA polymerase-IN-4
	DNA polymerase-IN-4 (Compd 5c), a coumarin derivative, exhibits antiretroviral activity, achieving an IC50 of 134.22 μM [1].
T74631	RNA polymerase II-IN-2
	RNA polymerase II-IN-2 (compound 20iii), a potent inhibitor of RNA polymerase II (Pol II) with a K i value of 9.5 nM, demonstrates cytotoxicity against cancer cells, exhibiting toxicity levels 2 and 5 times higher than α...
T74765	Viral polymerase-IN-1 hydrochloride
	Viral polymerase-IN-1 hydrochloride, a derivative of Gemcitabine, effectively inhibits influenza A and B virus infections, demonstrating IC90 values ranging from 11.4 to 15.9 μM, and possesses activity against SARS-CoV-2...
T79923	T7 RNA polymerase		DNA/RNA Synthesis
	T7 RNA polymerase, expressed by Escherichia coli from the T7 bacteriophage RNA polymerase gene, is a highly specific enzyme utilized for in vitro transcription (IVT) of mRNA. This polymerase requires Mg 2+ and selects on...		DNA/RNA Synthesis
T74630	RNA polymerase II-IN-1		DNA/RNA Synthesis
	RNA polymerase II-IN-1 (compound 19iv), an amatoxin, selectively inhibits RNA polymerase II (Pol II) with an IC50 of 36.66 nM. It exhibits heightened cytotoxicity towards cancer cells and reduced toxicity in normal cells...		DNA/RNA Synthesis
T22749	DR2313	DR 2313	PARP
	DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.		PARP
T6842	G007-LK		PARP , Wnt/beta-catenin
	G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.		PARP , Wnt/beta-catenin
T15639	K-756		PARP , Wnt/beta-catenin
	K-756 is a direct and selective inhibitor of tankyrase (TNKS), which inhibits the ADP-ribosylation activity of TNKS1 and TNKS2 (IC50s: 31 and 36 nM, respectively).		PARP , Wnt/beta-catenin
T8964	G244-LM		Others , PARP
	G244-LM is a potent and specific inhibitor of tankyrase 1/2. G244-LM inhibits Wnt signaling.		Others , PARP
T16761	RK-287107		Others , PARP
	RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).		Others , PARP
T21524	4-amino-1,8-Naphthalimide		PARP
	4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nM		PARP
T1807	JW 55	JW55	PARP , Wnt/beta-catenin
	JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2).		PARP , Wnt/beta-catenin
T3168	MN-64	MN64	Others , PARP , Wnt/beta-catenin
	MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.		Others , PARP , Wnt/beta-catenin
T6197	PJ34		PARP
	PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.		PARP
T6181	UPF 1069		PARP
	UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.		PARP
T6768	AZ6102		PARP , Wnt/beta-catenin
	AZ6102 is a potent TNKS1/2 inhibitor that has 100-fold selectivity against other PARP family enzymes and shows IC50 of 5 nM for Wnt pathway inhibition in DLD-1 cells.		PARP , Wnt/beta-catenin
T6578	ME0328		PARP
	ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.		PARP
T2484	AZD-2461		PARP
	AZD2461 is a novel PARP inhibitor.		PARP
T3062	WIKI4		PARP , Wnt/beta-catenin
	WIKI4 is a potent inhibitor of Wnt/β-catenin signaling and tankyrase 2 (TNKS2).		PARP , Wnt/beta-catenin
T50098	TIQ-A		PARP
	TIQ-A is a PARP1 inhibitor which involved in DNA single-strand break repair via the base excision repair pathway. PARP1 is triggered by DNA damage and its excessive activation has been proposed as a causative factor in m...		PARP
T22264	AZ9482		PARP
	AZ9482 is a selective and potent inhibitor of PARP featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent activity of centrosome declustering with EC50 of < 18 nM in HeLa cells.		PARP
T7042	1,5-Isoquinolinediol		PARP
	1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM). The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1, 5-Isoquinolinediol...		PARP
T4472	NMS-P118		PARP
	NMS-P118 is a potent, selective and orally available Inhibitor of PARP-1 for cancer therapy.		PARP
T6339	AG14361	AG 14361,AG-14361	PARP
	AG14361 is an effective inhibitor of PARP1 (Ki<5 nM).		PARP
T5058	Pamiparib	BGB-290	PARP
	Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor(IC50 of 0.9 nM and 0.5 nM for PARP1 and PARP2, respectively). It has potent PARP trapping, and capability to penetrate the brain, and can b...		PARP
T9593	Senaparib	IMP4297	PARP
	Senaparib (IMP4297) is a novel highly potent and selective oral PARP1/2 inhibitor with strong antitumor activity.		PARP
T9165	AZD5305		PARP
	AZD5305 is a potent, selective and oral active PARP inhibitor.		PARP
T4471	E7449	Stenoparib,UNII-9X5A2QIA7C	Others , PARP
	E7449 (UNII-9X5A2QIA7C) is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC50s of 2.0, 1.0, ～50 and ～50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using 32P-NAD+ as substrate.		Others , PARP
T22414	RBN012759		PARP
	RBN012759, a potent and selective PARP14 inhibitor, decreases pro-tumor macrophage function and elicits inflammatory responses in tumor explants.		PARP
T1767	BMH-21	BMH21	DNA/RNA Synthesis
	BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.		DNA/RNA Synthesis
T3649	BGP-15	BGP15,BGP-15 2HCl	PARP
	BGP-15 (BGP-15 2HCl) is a PARP inhibitor with protecting effect after ischemia-reperfusion injury.		PARP
T12695	RBN-2397		PARP
	RBN-2397 is a potent, selective and orally active accross species NAD+ competitive PARP7 inhibitor with IC50 less than 3 nM.		PARP
T5399	GeA-69		PARP
	GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays).		PARP
T9497	Niraparib tosylate monohyrate		PARP
	Niraparib, also know as MK-4827, is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. MK4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting...		PARP
T7896	BYK204165	RT-017290	PARP
	BYK204165 (RT-017290) is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay)		PARP
T9430	Venadaparib	NOV140101,IDX-1197	PARP
	Venadaparib (NOV140101) (IDX-1197) is a potent, selective and orally active PARP inhibitor with IC50s of 1.4 nM and 1.0 nM for PARP1 and PARP2, respectively. Venadaparib is insensitive to PARP-5. Venadaparib prevents the...		PARP
T2124	PJ34 hydrochloride	PJ34 HCl	PARP
	PJ34 hydrochloride (PJ34 HCl) is a potent specific inhibitor of PARPl/2.		PARP
T7439	3-Methoxybenzamide	3-MBA	PARP , Antibacterial , Transferase
	3-Methoxybenzamide (3-MBA) is a competitive inhibitor of poly(ADP-ribose) synthetase.		PARP , Antibacterial , Transferase
T1454	Acyclovir	Aciclovir,Acycloguanosine	Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic , HSV
	Acyclovir (Aciclovir) is a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus fam...
T1878	XAV-939	XAV939,NVP-XAV939	PARP , Wnt/beta-catenin
	XAV-939 (NVP-XAV939) is a Tankyrase (TNKS) inhibitor that inhibits TNKS1 and TNKS2 (IC50=11/4 nM). XAV-939 selectively inhibits Wnt/β-catenin-mediated transcription.		PARP , Wnt/beta-catenin
T9024	OUL35	NSC39047	Others , PARP
	OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.		Others , PARP
T6912	NU1025	NSC 696807	PARP
	NU1025 (NSC-696807) is a potent PARP inhibitor with IC50 of 400 nM.		PARP
T3489	Dasabuvir	ABT-333	HCV Protease
	Dasabuvir (ABT-333) is a non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent RNA polymerase, with potential activity against HCV. Upon administration and after intra...		HCV Protease
T6446	Clevudine	L-FMAU,Levovir	HBV , DNA/RNA Synthesis
	Clevudine (Levovir) is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate. The ...		HBV , DNA/RNA Synthesis
T3261	NVP-TNKS656	TNKS656	Apoptosis , PARP , Wnt/beta-catenin
	NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.		Apoptosis , PARP , Wnt/beta-catenin

Compounds

DNA polymerase-IN-1

T80644

Synonym:

Target: Antiviral, DNA/RNA Synthesis

Taq DNA polymerase

T79922

Synonym:

Target: DNA/RNA Synthesis

Poly(A) polymerase

T79926

Synonym:

Target: DNA/RNA Synthesis

DNA polymerase-IN-2

T79307

Synonym:

Target: DNA/RNA Synthesis

DNA polymerase-IN-3

T79308

Synonym:

Target: DNA/RNA Synthesis

DNA polymerase-IN-4

T82536

Synonym:

Target:

RNA polymerase II-IN-2

T74631

Synonym:

Target:

Viral polymerase-IN-1 hydrochloride

Target: DNA/RNA Synthesis

RNA polymerase II-IN-1

T74630

Synonym:

Target: DNA/RNA Synthesis

Target: PARP, Wnt/beta-catenin

K-756

T15639

Synonym:

Target: PARP, Wnt/beta-catenin

4-amino-1,8-Naphthalimide

Target: PARP, Wnt/beta-catenin

MN-64

T3168

Synonym: MN64

Target: Others, PARP, Wnt/beta-catenin

Target: PARP, Wnt/beta-catenin

Target: PARP, Wnt/beta-catenin

Synonym: AG 14361,AG-14361

Synonym: Stenoparib,UNII-9X5A2QIA7C

Target: DNA/RNA Synthesis

BGP-15

T3649

Synonym: BGP15,BGP-15 2HCl

Niraparib tosylate monohyrate

Synonym: NOV140101,IDX-1197

Target: PARP, Antibacterial, Transferase

Acyclovir

T1454

Synonym: Aciclovir,Acycloguanosine

Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic, HSV

XAV-939

T1878

Synonym: XAV939,NVP-XAV939

Target: PARP, Wnt/beta-catenin

Synonym: L-FMAU,Levovir

Target: HBV, DNA/RNA Synthesis

NVP-TNKS656

T3261

Synonym: TNKS656

Target: Apoptosis, PARP, Wnt/beta-catenin

Cat No.	Product Name	Synonyms	Targets
T8184	Fucosterol		PARP , Endogenous Metabolite , PPAR
	Fucosterol is isolated from E. stolonifera with anti-diabetic, anti-adipogenic and anti-cancer activities. It regulates adipogenesis via modulation of PPARα and C/EBPα expression.		PARP , Endogenous Metabolite , PPAR
T6S0139	Neobavaisoflavone		Apoptosis , DNA/RNA Synthesis
	1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si...		Apoptosis , DNA/RNA Synthesis
T3332	Isosteviol	(-)-Isosteviol	IL Receptor , Potassium Channel , TNF , NF-κB , Reactive Oxygen Species , COX , Topoisomerase
	Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside and its hydrolysis products, steviol, isosteviol and stevio...
T7443	4'-Methoxychalcone		PARP , PPAR
	4'-Methoxychalcone with a variety of pharmacological activities, such as anti-tumor and anti-inflammatory activities.		PARP , PPAR
T8150	Nudifloramide	1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide	PARP , Endogenous Metabolite
	Nudifloramide (1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide) is one of the end degradation products of nicotinamide-adenine dinucleotide (NAD).		PARP , Endogenous Metabolite
T5S2358	Dehydrocorydaline	Dehydrocorydalin,13-Methylpalmatine	BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
	1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimeriz...		BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
T6780	Benzamide	Amid kyseliny benzoove,Phenylcarboxyamide,Benzoylamide	PARP , Endogenous Metabolite
	Benzamide (Amid kyseliny benzoove), an inhibitor of poly(ADP-ribose) polymerase, is a derivative of benzoic acid.		PARP , Endogenous Metabolite
T2S2362	Dehydrocorydaline nitrate		BCL , Others , PARP , p38 MAPK , Caspase , Parasite , Autophagy
	1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effect of Corydalis Tuber on allergic reactions may be partially a...
T10990	Dehydrocorydaline chloride	13-Methylpalmatine chloride	BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
	Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.		BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
TN2883	3',4'-Dimethoxyflavone		Others , PARP
	3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities.		Others , PARP
T5S1805	5,7-Dihydroxychromone	5,7-Dihydroxy-4H-Chromen-4-One	Others , Virus Protease , PARP , Caspase , Nrf2
	1. 5,7-Dihydroxychromone (5,7-Dihydroxy-4H-Chromen-4-One) isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 2. 5,7-Dihydroxychromone exerts neuroprotective effect agai...		Others , Virus Protease , PARP , Caspase , Nrf2
T6194	Fidaxomicin	Tiacumicin B,OPT-80,Clostomicin B1,PAR-101	Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic
	Fidaxomicin (Tiacumicin B) is a semisynthetic macrolide antibiotic used to treat Clostridium difficile-associated diarrhea in adults. Fidaxomicin has minimal systemic absorption and has not been linked to serum enzyme el...		Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic
T8296	5,7,4'-Trimethoxyflavone	4',5,7-Trimethoxyflavone	Apoptosis , PARP , Caspase
	5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.		Apoptosis , PARP , Caspase
T2851	Daphnetin	7,8-Dihydroxycoumarin,Daphnetol	EGFR , PKA , PKC , Parasite , Autophagy
	Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-...		EGFR , PKA , PKC , Parasite , Autophagy
T4085	Paris saponin VII	Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII	Apoptosis , BCL , Others , PARP , p38 MAPK , Akt , Caspase , P-gp , Autophagy
	Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
T3376	Cynaroside	Luteoloside,Luteolin 7-β-D-Glucopyranoside,Luteolin 7-O-Glucoside,Luteolin 7-O-β-D-glucoside,Luteolin 7-glucoside	Others , Influenza Virus , DNA/RNA Synthesis
	Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation.		Others , Influenza Virus , DNA/RNA Synthesis
T14304	Aphidicolin		Others
	Aphidicolin, an antibiotic derived from the mold Cephalosporium aphidicola, is a potent inhibitor of DNA (deoxyribonucleic acid) synthesis, effectively hindering the proliferation of herpes simplex virus[2]. It targets D...		Others
T3772	Maslinic acid	2α-Hydroxyoleanoic Acid,2α-Hydroxyoleanolic acid,Crategolic acid	NF-κB , HIV Protease , DNA/RNA Synthesis , Antibacterial
	Maslinic acid (Crategolic acid) is a DNA polymerase B inhibitor.		NF-κB , HIV Protease , DNA/RNA Synthesis , Antibacterial
T7607	PSI-6130	R 1656	HCV Protease
	PSI-6130 (R 1656) is a potent and selective HCV NS5B polymerase inhibitor. PSI-6130 inhibits HCV replication with a mean IC50 of 0.6 μM.		HCV Protease
T37635	2'-Deoxyadenosine-5'-triphosphate trisodium	dATP trisodium	DNA/RNA Synthesis , Endogenous Metabolite
	2'-Deoxyadenosine-5'-triphosphate trisodium (dATP trisodium) is a nucleotide that serves as a substrate for DNA polymerase, which is used in cells for DNA synthesis or replication.		DNA/RNA Synthesis , Endogenous Metabolite
T5003	Rifamycin sodium	Rifamycin sodium salt	Antibacterial , Antibiotic
	Rifamycin sodium (Rifamycin sodium salt) salt is an antibiotic that inhibits bacterial DNA-dependent RNA polymerase. It is effective against Gram-positive bacteria.		Antibacterial , Antibiotic
T9086	Deoxythymidine-5'-triphosphate trisodium	dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),Deoxythymidine-5'-triphosphate (dTTP) trisodium salt	DNA/RNA Synthesis
	Deoxythymidine-5'-triphosphate trisodium (Deoxythymidine-5'-triphosphate (dTTP) trisodium salt) is one of the four natural deoxynucleotides. It is used for the biosynthesis of deoxyribonucleic acid by DNA polymerase and ...		DNA/RNA Synthesis
T1086	Vitamin D2	Calciferol,Ergocalciferol,Ercalciol	DNA/RNA Synthesis , Endogenous Metabolite
	Ergocalciferol (Vitamin D2 (Calciferol)) is a derivative of ergosterol formed by ultraviolet rays breaking of the C9-C10 bond with a strong inhibitory effect against bladder tumor promotion by sodium saccharin, and it in...		DNA/RNA Synthesis , Endogenous Metabolite
T1272	Cytarabine	Ara-C,Cytosine Arabinoside,Cytosine β-D-arabinofuranoside,Arabinocytidine	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy , HSV
	Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM). Cytarabine inhibits DNA polymerase and induces cell cycle arrest, autophagy, and apoptosis. Cytarabine has antitumor activity.
T8347	Rifamycin S		Reactive Oxygen Species , ROS , Antibacterial , Antibiotic
	Rifamycin S is a potent DNA-dependent RNA polymerase inhibitor,is a quinone and an antibiotic agnet against Gram-positive bacteria		Reactive Oxygen Species , ROS , Antibacterial , Antibiotic
T7961	N4-Benzoyl-2′-deoxycytidine		Others
	N4-Benzoyl-2′-deoxycytidine is a synthetic nucleoside analog of the natural nucleoside deoxycytidine (dC), a competitive inhibitor of DNA polymerase. In vitro studies have shown that it inhibits replication in viruses, b...		Others
T16223	N-Dodecyl-β-D-maltoside	Lauryl Maltoside	Others
	N-Dodecyl-β-D-maltoside (Lauryl Maltoside) has also been employed in applications such as in the purification and stabilization of RNA polymerase and the detection of protein-lipid interactions. N-Dodecyl-β-D-maltoside i...		Others
T2860	Vanillyl Alcohol	4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,Vanillin alcohol,Vanillic alcohol	Apoptosis , Others
	Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) possesses anti-angiogenic, anticonvulsive, anti-inflammatory, anti-oxidant, neuroprotective, and anti-nociceptive activities. Vanillyl alcohol can effectively inhibit ...		Apoptosis , Others
T40834	5-Hydroxymethyl-2'-deoxycytidine	5hmdC	PARP
	5-Hydroxymethyl-2'-deoxycytidine is an oxidized derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA, causing DNA damage reactions, chromosomal aberrations, replication fork damage, and loss of cell viability.5-Hydroxy...		PARP
T6S2391	L-Chicoric Acid	(-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,dicaffeoyltartaric acid	Others , HIV Protease
	L-Chicoric Acid (trans-Caffeoyltartaric acid) has been shown to inhibit hyaluronidase and HIV-1 integrase, and to possess phagoeytosis stimulatory activity in vitro and in vivo and antiviral acitivy. L-Chicoric acid may ...		Others , HIV Protease
T1591	Ancitabine hydrochloride	NSC 145668 HCl,Cyclocytidine hydrochloride,Cyclo-CMP hydrochloride,Cyclocytidine HCl,Cyclo-C	Others , DNA/RNA Synthesis , Autophagy
	Ancitabine hydrochloride (NSC 145668 HCl) is the hydrochloride salt of a cytarabine congener prodrug with antineoplastic activity. Upon administration, ancitabine is slowly hydrolyzed into cytarabine. Subsequently, cytar...		Others , DNA/RNA Synthesis , Autophagy
TN1134	Euscaphic acid		Apoptosis , LDL , PI3K , DNA/RNA Synthesis , NO Synthase , Prostaglandin Receptor
	Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of...
TN1163	2'-Hydroxychalcone		Others
	2'-Hydroxychalcone is a drug synthesis intermediate for the synthesis of flavonoids. 2'-Hydroxychalcone loaded in nanoemulsion showed fungicidal activity against Coccidioides parapsilosis in Danio rerio model.2'-Hydroxyc...		Others
T1558	Resveratrol	trans-Resveratrol,SRT 501	Apoptosis , Mitophagy , IκB/IKK , Lipoxygenase , Sirtuin , COX , NADPH , DNA/RNA Synthesis , Nrf2 , Antibacterial , Antibiotic , Autophagy , Antifungal
	Resveratrol (SRT 501) is a polyphenolic natural product, a plant antitoxin with antioxidant and chemopreventive activities. Resveratrol has a wide range of targets including COX, SIRT, LOC, etc. Resveratrol induces autop...
T15094	Dehydroaltenusin		DNA/RNA Synthesis
	Dehydroaltenusin is a selective eukaryotic DNA polymerase α inhibitor and a type of antibiotic produced by a fungus (IC50: 0.68 μM). Dehydroaltenusin inhibits mammalian pol α activity.		DNA/RNA Synthesis
TN5879	Edgeworin
	Edgeworin is a DNA polymerase beta (pol beta) inhibitor, it inhibits both the lyase and polymerase activities of DNA polymerase beta; it can potentiate the inhibitory action of the anticancer drug bleomycin in cultured A...
T39649	ε-Amanitin
	ε-Amanitin is a cyclic peptide obtained from various mushroom species. It exhibits a strong affinity for RNA polymerase II and effectively inhibits its activity.
TN6148	3-O-trans-p-Coumaroylmaslinic acid
	3-beta-O-(trans-p-Coumaroyl)maslinic acid is a DNA polymerase B" inhibitor. It shows antimicrobial activity on Gram-positive bacteria and yeasts.
TN2222	Sotetsuflavone		Others
	Sotetsuflavone, with an IC50 of 0.16 μM, stands as the most active compound in its series, acting as a potent inhibitor of DENV-NS5 RdRp (Dengue virus NS5 RNA-dependent RNA polymerase).		Others
T16673	Pseudouridimycin	PUM	Others
	Pseudouridimycin is a C-nucleoside analogue. Pseudouridimycin is an antibiotic and is a selective bacterial RNA polymerase (RNAP) inhibitor. It is effective against both Gram-negative and Gram-positive bacteria.		Others
T19463	N4-Acetylcytidine triphosphate	ac4CTP	Others
	N4-Acetylcytidine triphosphate is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro transcription .		Others
T19462	N4-Acetylcytidine triphosphate sodium	ac4CTP sodium	Others
	N4-Acetylcytidine triphosphate sodium is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro transcription.		Others
T39562	γ-Amanitin
	γ-Amanitin, an ADC (antibody-drug conjugate) cytotoxin isolated from mushrooms, inhibits RNA polymerase II, disrupting mRNA synthesis. It exhibits effects akin to those of α-Amanitin and β-Amanitin.
TMA0984	Cerevisterol		DNA/RNA Synthesis
	Cerevisterol is a cytotoxic steroid, can inhibit the activity of DNA polymerase alpha. It can stimulate NGF-mediated neurite outgrowth on PC12 cells.		DNA/RNA Synthesis
TN4046	Excisanin A		MMP , FAK , PARP , GSK-3 , NF-κB , Wnt/beta-catenin , Akt , Caspase , PI3K , Prostaglandin Receptor , JNK
	ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a potential anti-metastatic chemotherapeutic agent for the treatm...
T36667	2'-Deoxyadenosine-5'-triphosphate	dATP,Deoxyadenosine 5-triphosphate	DNA/RNA Synthesis , Endogenous Metabolite
	2'-Deoxyadenosine-5'-triphosphate (Deoxyadenosine 5-triphosphate) (dATP) is a naturally occurring small molecule nucleotide used in cells for DNA synthesis or replication. 2'-Deoxyadenosine-5'-triphosphate (dATP) is a su...		DNA/RNA Synthesis , Endogenous Metabolite
T73403	Aviculin
	Aviculin, a lignan glycoside, exhibits significant anticancer properties, particularly in inhibiting the metabolic activity of MCF-7 cells to below 50%, with an IC 50 value of 75.47 μM. It promotes apoptosis in breast ca...
T35779	Oosporein
	Oosporein is a mycotoxin that has been found inBeauveriaand has diverse biological activities.1,2It is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of 4.23 and 10.43 μM, respectiv...

Natural Products

Fucosterol

T8184

Synonym:

Target: PARP, Endogenous Metabolite, PPAR

Neobavaisoflavone

T6S0139

Synonym:

Target: Apoptosis, DNA/RNA Synthesis

Isosteviol

T3332

Synonym: (-)-Isosteviol

Target: IL Receptor, Potassium Channel, TNF, NF-κB, Reactive Oxygen Species, COX, Topoisomerase

Synonym: 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide

Target: PARP, Endogenous Metabolite

Dehydrocorydaline

T5S2358

Synonym: Dehydrocorydalin,13-Methylpalmatine

Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy

Benzamide

T6780

Synonym: Amid kyseliny benzoove,Phenylcarboxyamide,Benzoylamide

Target: PARP, Endogenous Metabolite

Dehydrocorydaline nitrate

T2S2362

Synonym:

Target: BCL, Others, PARP, p38 MAPK, Caspase, Parasite, Autophagy

Dehydrocorydaline chloride

T10990

Synonym: 13-Methylpalmatine chloride

Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy

3',4'-Dimethoxyflavone

TN2883

Synonym:

Target: Others, PARP

5,7-Dihydroxychromone

T5S1805

Synonym: 5,7-Dihydroxy-4H-Chromen-4-One

Target: Others, Virus Protease, PARP, Caspase, Nrf2

Fidaxomicin

T6194

Synonym: Tiacumicin B,OPT-80,Clostomicin B1,PAR-101

Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic

5,7,4'-Trimethoxyflavone

T8296

Synonym: 4',5,7-Trimethoxyflavone

Target: Apoptosis, PARP, Caspase

Daphnetin

T2851

Synonym: 7,8-Dihydroxycoumarin,Daphnetol

Target: EGFR, PKA, PKC, Parasite, Autophagy

Paris saponin VII

T4085

Synonym: Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII

Target: Apoptosis, BCL, Others, PARP, p38 MAPK, Akt, Caspase, P-gp, Autophagy

Cynaroside

T3376

Synonym: Luteoloside,Luteolin 7-β-D-Glucopyranoside,Luteolin 7-O-Glucoside,Luteolin 7-O-β-D-glucoside,Luteolin 7-glucoside

Target: Others, Influenza Virus, DNA/RNA Synthesis

Synonym: 2α-Hydroxyoleanoic Acid,2α-Hydroxyoleanolic acid,Crategolic acid

Target: NF-κB, HIV Protease, DNA/RNA Synthesis, Antibacterial

2'-Deoxyadenosine-5'-triphosphate trisodium

T37635

Synonym: dATP trisodium

Target: DNA/RNA Synthesis, Endogenous Metabolite

Rifamycin sodium

T5003

Synonym: Rifamycin sodium salt

Target: Antibacterial, Antibiotic

Deoxythymidine-5'-triphosphate trisodium

T9086

Synonym: dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),Deoxythymidine-5'-triphosphate (dTTP) trisodium salt

Target: DNA/RNA Synthesis

Vitamin D2

T1086

Synonym: Calciferol,Ergocalciferol,Ercalciol

Target: DNA/RNA Synthesis, Endogenous Metabolite

Cytarabine

T1272

Synonym: Ara-C,Cytosine Arabinoside,Cytosine β-D-arabinofuranoside,Arabinocytidine

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite, Autophagy, HSV

Rifamycin S

T8347

Synonym:

Target: Reactive Oxygen Species, ROS, Antibacterial, Antibiotic

N4-Benzoyl-2′-deoxycytidine

T7961

Synonym:

Target: Others

N-Dodecyl-β-D-maltoside

T16223

Synonym: Lauryl Maltoside

Target: Others

Vanillyl Alcohol

T2860

Synonym: 4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,Vanillin alcohol,Vanillic alcohol

Target: Apoptosis, Others

5-Hydroxymethyl-2'-deoxycytidine

Synonym: (-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,dicaffeoyltartaric acid

Target: Others, HIV Protease

Ancitabine hydrochloride

T1591

Synonym: NSC 145668 HCl,Cyclocytidine hydrochloride,Cyclo-CMP hydrochloride,Cyclocytidine HCl,Cyclo-C

Target: Others, DNA/RNA Synthesis, Autophagy

Euscaphic acid

TN1134

Synonym:

Target: Apoptosis, LDL, PI3K, DNA/RNA Synthesis, NO Synthase, Prostaglandin Receptor

Synonym: trans-Resveratrol,SRT 501

Target: Apoptosis, Mitophagy, IκB/IKK, Lipoxygenase, Sirtuin, COX, NADPH, DNA/RNA Synthesis, Nrf2, Antibacterial, Antibiotic, Autophagy, Antifungal

Dehydroaltenusin

T15094

Synonym:

Target: DNA/RNA Synthesis

3-O-trans-p-Coumaroylmaslinic acid

N4-Acetylcytidine triphosphate

T19463

Synonym: ac4CTP

Target: Others

N4-Acetylcytidine triphosphate sodium

T19462

Synonym: ac4CTP sodium

Target: DNA/RNA Synthesis

Excisanin A

TN4046

Synonym:

Target: MMP, FAK, PARP, GSK-3, NF-κB, Wnt/beta-catenin, Akt, Caspase, PI3K, Prostaglandin Receptor, JNK

2'-Deoxyadenosine-5'-triphosphate

T36667

Synonym: dATP,Deoxyadenosine 5-triphosphate

Target: DNA/RNA Synthesis, Endogenous Metabolite

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-00427	DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant	Colwellia psychrerythraea	E. coli
	DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant is expressed in E. coli.
TMPH-00426	DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant (His)	Colwellia psychrerythraea	E. coli
	DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant (His) is expressed in E. coli.
TMPH-00613	DNA polymerase II Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	Thought to be involved in DNA repair and/or mutagenesis. Its processivity is enhanced by the beta sliding clamp (dnaN) and clamp loader.
TMPH-00523	DNA-directed DNA polymerase Protein, Enterobacteria phage RB69, Recombinant (His & Myc)	Escherichia phage RB69	E. coli
	Replicates the viral genomic DNA. This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction for proofreadin...
TMPH-00360	DNA polymerase II large subunit Protein, Cenarchaeum symbiosum, Recombinant	Cenarchaeum symbiosum	E. coli
	Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicativ...
TMPY-01188	PARP Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Poly (ADP-ribose) polymerase 1(PRAP1), also known as NAD(+) ADP-ribosyltransferase 1(ADPRT), is a chromatin-associated enzyme that modifies various nuclear proteins by poly(ADP-ribosyl)ation. The ADP-D-ribosyl group of N...
TMPJ-00792	DNA PolymeraseBeta Protein, Human, Recombinant (His)	Human	E. coli
	Human DNA polymerase β is constitutively expressed in cells. It fills in gaps in DNA that are formed following base excision repair. Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-p...
TMPH-00533	T7 RNA polymerase Protein, Enterobacteria phage T7, Recombinant (His & Myc)	Escherichia phage T7	E. coli
	Highly processive DNA-dependent RNA polymerase that catalyzes the transcription of class II and class III viral genes. Recognizes a specific promoter sequence and enters first into an 'abortive phase' where very short tr...
TMPY-06071	SARS-CoV-2 RNA-dependent RNA polymerase/RDRP Protein (His)	SARS-CoV-2	Baculovirus-Insect Cells

TMPH-02356	Influenza A H1N1 (strain A/USA:Huston/AA/1945) Polymerase acidic Protein (His)	H1N1	Yeast
	Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism call...
TMPH-02357	Influenza A H3N2 (strain A/X-31) Polymerase acidic Protein (His)	H3N2	E. coli
	Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism call...
TMPH-02884	CTDP1 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II. Plays a role in the exit...
TMPH-01450	Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) DNA polymerase processivity factor (His)	HHV-6A	Yeast
	Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) DNA polymerase processivity factor (His) is expressed in Yeast.
TMPY-02421	PARP3 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Poly(ADP-ribose) polymerase 3 (PARP3) is an important member of the PARP family and shares high structural similarities with both PARP1 and PARP2. Poly(ADP-ribose) polymerase 3 (PARP3), a critical player in cellular resp...
TMPY-02465	PARP Protein, Mouse, Recombinant (His)	Mouse	Baculovirus-Insect Cells
	Poly (ADP-ribose) polymerase 1(PRAP1), also known as NAD(+) ADP-ribosyltransferase 1(ADPRT), is a chromatin-associated enzyme that modifies various nuclear proteins by poly(ADP-ribosyl)ation. The ADP-D-ribosyl group of N...
TMPH-02580	CHRAC1 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Forms a complex with DNA polymerase epsilon subunit POLE3 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome remodeling activity of ISWI/SNF2H and ACF1. Does not enhance nucleosome sl...
TMPH-03230	PHB depolymerase Protein, Ralstonia pickettii, Recombinant (His)	Ralstonia pickettii	E. coli
	This protein degrades water-insoluble and water-soluble PHB to monomeric D(-)-3-hydroxybutyrate.
TMPY-05822	Hepatitis B Virus (HBV)(ayw/France/Tiollais/1979) Capsid protein (His)	HBV-D	E. coli
	Hepatitis B virus (HBV) capsid assembly is a critical step in the propagation of the virus and is mediated by the core protein. The first cytoplasmic step in the formation of an infectious HBV virion is the formation of ...
TMPH-03734	Zaire ebolavirus (strain Mayinga-76) L Protein (His)	ZEBOV	E. coli
	RNA-directed RNA polymerase that catalyzes the transcription of viral mRNAs, their capping and polyadenylation. The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N). The viral polymeras...
TMPH-03735	Zaire ebolavirus (strain Kikwit-95) L Protein (His & Myc)	ZEBOV	E. coli
	RNA-directed RNA polymerase that catalyzes the transcription of viral mRNAs, their capping and polyadenylation. The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N). The viral polymeras...
TMPH-01247	POLR3K Protein, Human, Recombinant (His)	Human	Baculovirus
	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs....
TMPH-00811	Hepatitis delta virus genotype I (HDV) Small delta antigen Protein (His & Myc)	HDV	Yeast
	Promotes both transcription and replication of genomic RNA. Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal. May interact with host RNA polymerase II th...
TMPH-00094	HSP21, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc)	Arabidopsis thaliana	E. coli
	Chaperone protein required for seedling and chloroplast development under heat stress, probably by maintaining plastid-encoded RNA polymerase (PEP)-dependent transcription.
TMPH-01648	MED1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory...
TMPH-02384	Lake Victoria marburgvirus (MARV) (strain Popp-67) L Protein (His & Myc)	MARV	E. coli
	RNA-directed RNA polymerase that catalyzes the transcription of viral mRNAs, their capping and polyadenylation. The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N). The viral polymeras...
TMPH-03184	P2 Protein, Pseudomonas phage phi6, Recombinant (His & Myc)	Pseudomonas phage phi6	E. coli
	Rna-dependent RNA polymerase part of the packaging complex that packages the viral RNA segments, replicate them into a double-stranded form and transcribe them.
TMPY-05024	Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-NS5 protein (His)	ZIKV	Baculovirus-Insect Cells
	Zika virus NS5 is involved in methytransferase and RNA guanylytransferase activities and capping and synthesis of RNA. And, NS5 is also an RNA-dependent RNA polymerase.
TMPJ-01067	TFIIB Protein, Human, Recombinant (GST)	Human	E. coli
	Transcription Initiation Factor IIB (TFIIB) is an essential factor for transcription by RNA Polymerase II. TFIIB localizes to the nucleus where it forms a complex (the DAB complex) with transcription factor IID and IIA. ...
TMPH-00717	Protease 7 Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Protease that can cleave T7 RNA polymerase, ferric enterobactin receptor protein (FEP), antimicrobial peptide protamine and other proteins. This protease has a specificity for paired basic residues.
TMPH-00680	Protease 7 Protein, E. coli O157:H7, Recombinant (G236K K237G, His & SUMO)	E. coli	E. coli
	Protease that can cleave T7 RNA polymerase, ferric enterobactin receptor protein (FEP), antimicrobial peptide protamine and other proteins. This protease has a specificity for paired basic residues.
TMPH-01245	POLM Protein, Human, Recombinant (His & Myc)	Human	Baculovirus
	Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.
TMPH-01244	POLM Protein, Human, Recombinant (His)	Human	E. coli
	Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.
TMPH-00727	FliA Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.
TMPH-01798	Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO)	Human	in vitro E. coli expression system
	Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream...
TMPH-03229	Rabies virus (RABV) (strain PM) Phosphoprotein (His)	RABV	E. coli
	Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from...
TMPH-01246	POLR3A Protein, Human, Recombinant (His)	Human	E. coli
	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs,...
TMPJ-01443	HChFc2 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Host cell factor 2(HCFC2) is a cytoplasmic protein. It contains 2 fibronectin type-III domains.HCFC2 binds KMT2A/MLL1, as component of the MLL1/MLL complex.Hcfc2 negative regulation of transcription from RNA polymerase I...
TMPH-00729	RpoH Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. Intrac...
TMPH-00728	FliA Protein, E. coli, Recombinant	E. coli	E. coli
	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.
TMPH-01799	Nucleolar transcription factor 1 Protein, Human, Recombinant (E. coli, His & SUMO)	Human	E. coli
	Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream...
TMPK-01342	3CLpro/3C-like Protease Protein (A191V), SARS-COV-2, Recombinant	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPK-01338	3CLpro/3C-like Protease Protein (H172Y), SARS-COV-2, Recombinant	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPK-01340	3CLpro/3C-like Protease Protein (F140A), SARS-COV-2, Recombinant	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPH-00532	SSB Protein, Enterobacteria phage T7, Recombinant	Enterobacteria phage T7	Yeast
	Single-stranded DNA-binding protein that participates in viral DNA replication, formation of concatemers, recombination and repair of double-stranded breaks. Coats the lagging-strand ssDNA as the replication fork advance...
TMPK-01348	3CLpro/3C-like Protease Protein, SARS-COV-2, Recombinant (aa 1-306)	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPK-01347	3CLpro/3C-like Protease Protein (E166A), SARS-COV-2, Recombinant	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPK-01337	3CLpro/3C-like Protease Protein (Q189K), SARS-COV-2, Recombinant	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPK-01336	3CLpro/3C-like Protease Protein (L50F, E166V), SARS-COV-2, Recombinant	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPK-01335	3CLpro/3C-like Protease Protein (E166V), SARS-COV-2, Recombinant	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
TMPK-01344	3CLpro/3C-like Protease Protein (L167F), SARS-COV-2, Recombinant	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and al...
------------------------ More ------------------------

DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant

TMPH-00427

Species: Colwellia psychrerythraea

Expression System: E. coli

DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant (His)

TMPH-00426

Species: Colwellia psychrerythraea

Expression System: E. coli

DNA polymerase II Protein, E. coli, Recombinant (His & Myc)

TMPH-00613

Species: E. coli

Expression System: E. coli

DNA-directed DNA polymerase Protein, Enterobacteria phage RB69, Recombinant (His & Myc)

TMPH-00523

Species: Escherichia phage RB69

Expression System: E. coli

DNA polymerase II large subunit Protein, Cenarchaeum symbiosum, Recombinant

TMPH-00360

Species: Cenarchaeum symbiosum

Expression System: E. coli

PARP Protein, Human, Recombinant (His)

TMPY-01188

Species: Human

Expression System: Baculovirus-Insect Cells

DNA PolymeraseBeta Protein, Human, Recombinant (His)

TMPJ-00792

Species: Human

Expression System: E. coli

T7 RNA polymerase Protein, Enterobacteria phage T7, Recombinant (His & Myc)

TMPH-00533

Species: Escherichia phage T7

Expression System: E. coli

SARS-CoV-2 RNA-dependent RNA polymerase/RDRP Protein (His)

TMPY-06071

Species: SARS-CoV-2

Expression System: Baculovirus-Insect Cells

Influenza A H1N1 (strain A/USA:Huston/AA/1945) Polymerase acidic Protein (His)

TMPH-02356

Species: H1N1

Expression System: Yeast

Influenza A H3N2 (strain A/X-31) Polymerase acidic Protein (His)

TMPH-02357

Species: H3N2

Expression System: E. coli

CTDP1 Protein, Mouse, Recombinant (His & Myc)

TMPH-02884

Species: Mouse

Expression System: E. coli

Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) DNA polymerase processivity factor (His)

TMPH-01450

Species: HHV-6A

Expression System: Yeast

PARP3 Protein, Human, Recombinant (His & GST)

TMPY-02421

Species: Human

Expression System: Baculovirus-Insect Cells

PARP Protein, Mouse, Recombinant (His)

TMPY-02465

Species: Mouse

Expression System: Baculovirus-Insect Cells

CHRAC1 Protein, Mouse, Recombinant (His & Myc)

TMPH-02580

Species: Mouse

Expression System: E. coli

PHB depolymerase Protein, Ralstonia pickettii, Recombinant (His)

TMPH-03230

Species: Ralstonia pickettii

Expression System: E. coli

Hepatitis B Virus (HBV)(ayw/France/Tiollais/1979) Capsid protein (His)

TMPY-05822

Species: HBV-D

Expression System: E. coli

Zaire ebolavirus (strain Mayinga-76) L Protein (His)

TMPH-03734

Species: ZEBOV

Expression System: E. coli

Zaire ebolavirus (strain Kikwit-95) L Protein (His & Myc)

TMPH-03735

Species: ZEBOV

Expression System: E. coli

POLR3K Protein, Human, Recombinant (His)

TMPH-01247

Species: Human

Expression System: Baculovirus

Hepatitis delta virus genotype I (HDV) Small delta antigen Protein (His & Myc)

TMPH-00811

Species: HDV

Expression System: Yeast

HSP21, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc)

TMPH-00094

Species: Arabidopsis thaliana

Expression System: E. coli

MED1 Protein, Human, Recombinant (His & SUMO)

TMPH-01648

Species: Human

Expression System: E. coli

Lake Victoria marburgvirus (MARV) (strain Popp-67) L Protein (His & Myc)

TMPH-02384

Species: MARV

Expression System: E. coli

P2 Protein, Pseudomonas phage phi6, Recombinant (His & Myc)

TMPH-03184

Species: Pseudomonas phage phi6

Expression System: E. coli

Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-NS5 protein (His)

TMPY-05024

Species: ZIKV

Expression System: Baculovirus-Insect Cells

TFIIB Protein, Human, Recombinant (GST)

TMPJ-01067

Species: Human

Expression System: E. coli

Protease 7 Protein, E. coli, Recombinant (His)

TMPH-00717

Species: E. coli

Expression System: E. coli

Protease 7 Protein, E. coli O157:H7, Recombinant (G236K K237G, His & SUMO)

TMPH-00680

Species: E. coli

Expression System: E. coli

POLM Protein, Human, Recombinant (His & Myc)

TMPH-01245

Species: Human

Expression System: Baculovirus

POLM Protein, Human, Recombinant (His)

TMPH-01244

Species: Human

Expression System: E. coli

FliA Protein, E. coli, Recombinant (His)

TMPH-00727

Species: E. coli

Expression System: E. coli

Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO)

TMPH-01798

Species: Human

Expression System: in vitro E. coli expression system

Rabies virus (RABV) (strain PM) Phosphoprotein (His)

TMPH-03229

Species: RABV

Expression System: E. coli

POLR3A Protein, Human, Recombinant (His)

TMPH-01246

Species: Human

Expression System: E. coli

HChFc2 Protein, Mouse, Recombinant (His)

TMPJ-01443

Species: Mouse

Expression System: E. coli

RpoH Protein, E. coli, Recombinant (His & Myc)

TMPH-00729

Species: E. coli

Expression System: E. coli

FliA Protein, E. coli, Recombinant

TMPH-00728

Species: E. coli

Expression System: E. coli

Nucleolar transcription factor 1 Protein, Human, Recombinant (E. coli, His & SUMO)

TMPH-01799

Species: Human

Expression System: E. coli

3CLpro/3C-like Protease Protein (A191V), SARS-COV-2, Recombinant

TMPK-01342

Species: SARS-CoV-2

Expression System: E. coli

3CLpro/3C-like Protease Protein (H172Y), SARS-COV-2, Recombinant

TMPK-01338

Species: SARS-CoV-2

Expression System: E. coli

3CLpro/3C-like Protease Protein (F140A), SARS-COV-2, Recombinant

TMPK-01340

Species: SARS-CoV-2

Expression System: E. coli

SSB Protein, Enterobacteria phage T7, Recombinant

TMPH-00532

Species: Enterobacteria phage T7

Expression System: Yeast

3CLpro/3C-like Protease Protein, SARS-COV-2, Recombinant (aa 1-306)

TMPK-01348

Species: SARS-CoV-2

Expression System: E. coli

3CLpro/3C-like Protease Protein (E166A), SARS-COV-2, Recombinant

TMPK-01347

Species: SARS-CoV-2

Expression System: E. coli

3CLpro/3C-like Protease Protein (Q189K), SARS-COV-2, Recombinant

TMPK-01337

Species: SARS-CoV-2

Expression System: E. coli

3CLpro/3C-like Protease Protein (L50F, E166V), SARS-COV-2, Recombinant

TMPK-01336

Species: SARS-CoV-2

Expression System: E. coli

3CLpro/3C-like Protease Protein (E166V), SARS-COV-2, Recombinant

TMPK-01335

Species: SARS-CoV-2

Expression System: E. coli

3CLpro/3C-like Protease Protein (L167F), SARS-COV-2, Recombinant

TMPK-01344

Species: SARS-CoV-2

Expression System: E. coli

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Cat No.	Product Name
L6120	Flavonoid Natural Product Library	477 compounds
	A unique collection of 477 flavonoids can be used for high throughput and high content screening；
L3800	NF-κB Signaling Compound Library	740 compounds
	A unique collection of 740 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L1710	Anti-COVID-19 Compound Library	1160 compounds
	A unique collection of 1160 compounds with confirmed anti-SARS-CoV-2 activity or potential activity and part of them are broad-spectrum antiviral agents；

Libraries

Flavonoid Natural Product Library

L6120

Compounds: 477

NF-κB Signaling Compound Library

L3800

Compounds: 740

Anti-COVID-19 Compound Library

L1710

Compounds: 1160