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pioglitazone

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    11
    TargetMol | Inhibitors_Agonists
  • Isotope Products
    4
    TargetMol | Isotope_Products
Pioglitazone
U 72107
T0214111025-46-8
Pioglitazone (U 72107) is an insulin sensitizing agent and thiazolidinedione indicated for the treatment of type 2 diabetes, and has been linked to rare instances of acute liver injury.
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TargetMol | Inhibitor Hot
Pioglitazone hydrochloride
U-72107E, U 72107A, Pioglitazone HCl, AD 4833
T0214L112529-15-4
Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity.
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Pioglitazone-d4
U 72107 D4
T124791134163-29-3
Pioglitazone D4 is a deuterium labeled Pioglitazone. Pioglitazone is a agonist of PPARγ .
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7-10 days
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pioglitazone potassium
T618361266523-09-4
Pioglitazone potassium (U 72107) is an orally active, selective agonist of peroxisome proliferator-activated receptor gamma (PPARγ), exhibiting high-affinity binding to the ligand-binding domain of PPARγ with EC50 values of 0.93 μM for human and 0.99 μM for mouse PPARγ. It has applications in diabetes research [2] [3] [4].
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1-2 weeks
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(R)-Pioglitazone
(R)-U 72107
T88433959687-65-1
(R)-Pioglitazone ((+)-pioglitazone), the R enantiomer of Pioglitazone, serves as a selective and orally active peroxisome proliferator-activated receptor (PPARγ) agonist. It exhibits high-affinity binding to the PPARγ ligand-binding domain and is utilized in research related to Alzheimers disease.
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10-14 weeks
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Hydroxy Pioglitazone M-IV-d4
TMIH-02671188263-49-1
Hydroxy Pioglitazone M-IV-d4 is a deuterated compound of Hydroxy Pioglitazone M-IV.
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7-10 days
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Keto Pioglitazone-d4
TMIJ-00931215370-26-5
Keto Pioglitazone-d4 is a deuterated compound of Keto Pioglitazone. Keto Pioglitazone has a CAS number of 146062-45-5. Ketopioglitazone is an active metabolite of pioglitazone.
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20 days
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Ketopioglitazone
Keto pioglitazone,Pioglitazone metabolite M3
T20465146062-45-5
Ketopioglitazone is an active metabolite of pioglitazone.
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Leriglitazone
Hydroxypioglitazone
T15736146062-44-4
Leriglitazone, a metabolite of pioglitazone, binds to the PPARγ C-terminal ligand-binding domain (Ki: 1.2 μM) and induces transcriptional efficacy of the PPARγ (EC50: 680 nM). Leriglitazone PioOH is a PPARγ agonist, stabilizes the PPARγ activation functio
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DRX-065
DRX065, DRX 065, deuterated R-enantiomer of pioglitazone
T272101259828-75-5
DRX-065 is a stabilized and deuterated R-enantiomer of pioglitazone. DRX-065 has pharmacological properties desirable for the treatment of NASH (mitochondrial function modulation, non-steroidal anti-inflammatory effects, and glucose lowering effects) with
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10-14 weeks
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leriglitazone hydrochloride
T73842146062-46-6
Leriglitazone (Hydroxypioglitazone) hydrochloride, a pioglitazone metabolite, acts as a PPARγ agonist, effectively stabilizing the PPARγ activation function-2 (AF-2) co-activator binding surface to enhance co-activator binding, which results in a modest improvement in transcriptional efficacy. It binds to the PPARγ C-terminal ligand-binding domain (LBD) with a dissociation constant (K i) of 1.2 μM and demonstrates transcriptional efficacy with an effective concentration (EC 50) of 680 nM [1].
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