phytosphingosine

Phytosphingosine is a phospholipid with anticancer properties. In cancer cells, Phytosphingosine induces cell apoptosis through activation of caspase 8 and translocation of Bax.

2-Aminooctadecane-1,3,4-Triol (Phytosphingosine) is a natural product.

EOP (t18:0/30:0/18:2) (C48:2 EOP (t18:0/30:0w18:2 (9Z,12Z)); N-(30-Linoleoyloxy-triacontanoyl)-phytosphingosine) is a phytoceramide-based compound resembling EOS. This compound is synthesized by esterifying ω-hydroxy very long-chain ceramides (C28-36) with the essential fatty acid linoleic acid. EOP (t18:0/30:0/18:2) has been utilized as a component in models of stratum corneum lipid mixtures.

C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid present in Saccharomyces cerevisiae, wheat grains, and the mammalian epidermal stratum corneum, composed of a phytosphingosine backbone amide-linked to a C18 fatty acid chain, C18 Phytoceramide regulates apoptosis, cell differentiation, smooth muscle cell proliferation, and mitochondrial respiratory chain activity while inhibiting IL-4, TNF-α, c-Jun, and NF-κB expression in histone-stimulated murine skin tissue, supporting its use in dermatological, inflammatory, and cosmetic skin barrier research.

C22 Phytoceramide (t18:0/22:0) is a lipid molecule that can be used in life science related research. The CAS number of C22 Phytoceramide (t18:0/22:0) is 164576-03-8.

C6 Phytoceramide (t18:0/6:0) is a lipid molecule that can be used in life science related research. The CAS number of C6 Phytoceramide (t18:0/6:0) is 249728-94-7.

C8 Phytoceramide (t18:0/8:0) is a lipid molecule that can be used in life science related research. The CAS number of C8 Phytoceramide (t18:0/8:0) is 249728-93-6.

Phytosphingosine-d7 (4-Hydroxysphinganine-d7) is a deuterium-labeled version of Phytosphingosine. This phospholipid exhibits anti-inflammatory, antibacterial, and anticancer properties and can induce apoptosis. Additionally, Phytosphingosine acts as an immunomodulator and is useful for studying inflammatory skin conditions. It also serves as a GPR120 activator with an IC50 of 33.4 μM, relevant in type 2 diabetes research.

N-Butyroyl Phytosphingosine is a lipid molecule characterized by an amide group, a primary alcohol, two secondary alcohols, and a C18 carbon chain.

C23 Phytoceramide (t18:0/23:0) is a long-chain sphingolipid identified in C. sinensis.

C24 Phytosphingosine (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C24 Phytosphingosine (t18:0/24:0) is composed of a phytosphingosine backbone amine-linked to a C24 fatty acid chain. It has been used with other ceramides to create stratum corneum substitutes to study percutaneous penetration and psoriasis in vitro. In a stratum corneum model of healthy skin, the incorporation of long-chain-containing phytoceramides, such as C24 phytosphingosine (t18:0/24:0), increases permeability of the membrane in comparison with incorporation of dihydroceramides.

PHYTOSPHINGOSINE (Standard) is a reference standard for research and analysis in studies involving PHYTOSPHINGOSINE. Phytosphingosine is a phospholipid with anticancer properties. In cancer cells, Phytosphingosine induces cell apoptosis through activation of caspase 8 and translocation of Bax.

Tetraacetylphytosphingosine is a sphingolipid metabolite produced through the acetylation of plant sphingosine. It functions as an angiogenesis inhibitor by suppressing the activation of MAPK and increasing intracellular calcium ions. Additionally, Tetraacetylphytosphingosine induces apoptosis in HaCaT cells.

N-Acetylphytosphingosine (NAPS), a sphingolipid derivative, induces apoptosis (Apoptosis) through mitochondrial-dependent activation of Bak, exhibiting antitumor activity.

Ceramide 1 A is a waxy lipid compound that is a lipid in the top skin layer. It has a special molecular structure because it contains a linoleic acid linked to a long chain omega-hydroxy acid.

C16 Phytoceramide (t18:0/16:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C16 Phytoceramide (t18:0/16:0) is composed of a phytosphingosine backbone amine-linked to a C16 fatty acid chain. The levels of C16 phytoceramide (t18:0/16:0) increase following heat stress in S. cerevisiae. It has been used with other ceramides to create stratum corneum substitutes to study percutaneous penetration and psoriasis in vitro.