43
7
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5051 | Isopropamide Iodide | AChR | |
Isopropamide iodide is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders. It also acts as a muscarinic receptor antagonist which can be applied to the t... | |||
T38612 | Linaprazan glurate | Others | |
Linaprazan glurate inhibits exogenously or endogenously stimulated gastric acid secretion. Linaprazan glurate can be used in studies about gastrointestinal inflammatory diseases and peptic ulcer diseases. | |||
T4981 | Anisotropine Methylbromide | Prostaglandin Receptor , AChR | |
Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion. | |||
T15500 | HPi1 | Others , Antibacterial | |
HPi1 is a selective and orally active antimicrobial against Helicobacter pylori (IC50: 0.24 μM and a MIC of 0.08-0.16 μg/mL). HPi1 is inactive against other Xaliproden, including the gut commensals, Lactobacillus reuteri... | |||
T0044 | Oxethazaine | Oxetacaine | HBV , Sodium Channel |
Oxethazaine (Oxetacaine), a topical anesthetic, is used to prevent acid-induced esophageal pain. | |||
T1734 | Rabeprazole Sulfide | Rabeprazole Related Compound E | Proton pump , Antibacterial |
Rabeprazole Sulfide (Rabeprazole Related Compound E) is an antiulcer drug in the class of proton pump inhibitors. | |||
T0992 | Carbenoxolone disodium | Biogastrone,Duogastrone,Bioral | Gap Junction Protein |
Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise, ... | |||
T8388 | Vonoprazan | TAK-438 (free base) | Proton pump |
Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis | |||
T21254 | Vonoprazan Fumarate | TAK-438,TAK 438,Vonoprazan Fumurate,TAK438 | Proton pump |
Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion. Vonoprazan Fumarate (TAK438) inhibited H+,K+-ATPase activity in porcine gastric microsomes with IC50 value of 19... | |||
T25939 | Pepticinnamin E | ||
Pepticinnamin E is a naturally occurring bisubstrate farnesyltransferase inhibitor. | |||
T29015 | Trithiozine | Tresanil,Sulmetozine,Tritiozinum,Tritiozine,Tritiozina | Others |
Trithiozine (Tritiozinum) exhibits antisecretory and antiulcer capacity. Trithiozine can be used for research on the treatment of peptic ulcer disease and hypersecretory disorders. | |||
T25737 | Linetastine | TMK 688,TMK-688,TMK688 | Lipoxygenase , LTR , Histamine Receptor |
Linetastine (TMK-688) is a 5-lipoxygenase inhibitor (5-LOX) that inhibits leukotriene production and antagonizes the effects of histamine.Linetastine is used in studies of asthma, atherosclerosis, and peptic ulcers. | |||
T0246L | Betahistine mesylate | Extovyl,Melopat,Meginalisk | Histamine Receptor |
Betahistine mesylate (Extovyl) is a histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers. | |||
T10221 | Abeprazan hydrochloride | DWP14012 hydrochloride,Fexuprazan hydrochloride | Proton pump |
Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPase by competitive binding to potassium ions without acid activat... | |||
T4195 | Betahistine | PT 9 base,Vasomotal,Serc base | Histamine Receptor |
Betahistine (Vasomotal) is a histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers. Betahisti... | |||
T0786 | Clidinium bromide | Ro 2-3773 | AChR |
Clidinium bromide (Ro 2-3773) , a synthetic anticholinergic agent, has been shown in experimental and clinical researchers to have a pronounced antisecretory and antispasmodic effect on the gastrointestinal tract. It can... | |||
T27640 | Itriglumide | CR-2945,CR2945,CR 2945 | |
Itriglumide, a CCK2 receptor antagonist, is used potentially for the treatment of peptic ulcers, dyspepsia, and gastroesophageal reflux disease (GERD). | |||
T31743 | Famotine hydrochloride | Famotine HCl,UK-2054 | |
Famotine Hydrochloride is a histamine H2 receptor antagonist that suppresses acid production in the stomach and commonly treats peptic ulcer disease and gastroesophageal reflux disease. | |||
T32224 | Isopropamide | Priazimide,Dipramide,Piaccamide,Chloroisopropamide,Dipramid | |
Isopropamide (R5) is a long-acting anticholinergic drug. It is used to treat peptic ulcers and other gastrointestinal disorders involving excess gastric acid (gastrointestinal acidosis) and hyperactivity. | |||
T34936 | Tridihexethyl chloride | Propethonum,Pathilon,Tridihexethyl | |
Tridihexethyl is an anticholinergic, antimuscarinic, and antispasmolytic drug, which can be used to treat acquired nystagmus or peptic ulcer disease. | |||
T14051 | 5-Hydroxylansoprazole | AG1908 | Proton pump |
5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole, a gastric proton-pump inhibitor that effectively treats various peptic diseases[1][2]. The metabolism of Lansoprazole occurs through CYP2C19, result... | |||
T68206 | Arbortristoside A | ||
Arbortristoside A is an anti-inflammatory and antinociceptive. This activity may be due to the inhibiting effect of prostaglandin, histamine and serotonin. Arbortristoside A has also been shown to act on ulcerations and ... | |||
T70127 | Famotine | ||
Famotine is a histamine H2 receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. | |||
T2138L | Oxyphencyclimine | Oxiphencycliminum,Antulcus,Zamanil,Manir,Caridan,Naridan | |
Oxyphencyclimine is a muscarinic receptor antagonist (MRA) anticholinergic drug used to treat peptic ulcers. | |||
T70090 | Nizatidine amide | ||
Nizatidine amide is a histamine H2 receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. | |||
T68725 | Famotidine propanamide | ||
Famotidine propanamide is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. | |||
T12914 | Siltenzepine | Others | |
Siltenzepine is an agent of anti-acid agent,and used in the treatment of peptic ulcers. | |||
T71801 | Arbaprostil | ||
Arbaprostil is a synthetic prostaglandin E analog that protects gastric mucosa, prevents ulceration, and promotes healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inh... | |||
T19929 | Ranitidine-S-oxide | ||
Ranitidine-S-oxide is a metabolite of Ranitidine. It is commonly used in the treatment of peptic ulcer disease, Zollinger–Ellison syndrome,and gastroesophageal reflux disease. | |||
T61228 | Pirenzepine | ||
Pirenzepine (LS 519 free base) is a selective antagonist of the M1 muscarinic acetylcholine receptor (mAChR). It effectively inhibits gastric acid secretion and reduces muscle spasm, making it a valuable compound for inv... | |||
T71509 | Famotidine sulfamoyl propanamide | ||
Famotidine sulfamoyl propanamide is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. | |||
T71485 | Famotidine propionic acid | ||
Famotidine propionic acid is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. | |||
T71049 | Famotidine disulfide | ||
Famotidine disulfide is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. | |||
T71980 | Omeprazole acid | ||
Omeprazole acid is a medication used in the treatment of gastroesophageal reflux disease, peptic ulcer disease, and Zollinger–Ellison syndrome. It is also used to prevent upper gastrointestinal bleeding in people who are... | |||
T33314 | Methantheline Bromide | Frenogastrico,Dixamone bromide,Banthine,Asabaine,Methanthelinium bromide | |
Methantheline Bromide is a synthetic spasmolytic used to relieve cramps or spasms of the stomach, bowel, and bladder. It is also useful for intestinal or gastric ulcers (peptic ulcer disease), intestinal problems, pancre... | |||
T25104 | Aprofene | aprophen,Aprofenum | |
Aprofene (Aprophen) is an antagonist of muscarinic and nicotinic acetylcholine receptors. It may be used in the therapy of peptic ulcers, endarteritis (inflammation of the inner shell of the artery), cholecystitis (infla... | |||
T78237 | Urease-IN-6 | ||
Urease-IN-6, a potent Urease inhibitor, exhibits an IC50 value of 14.2 μM and is utilized in the research of peptic and gastric ulcers [1]. | |||
T79656 | Urease-IN-8 | ||
Urease-IN-8 (Compound 5e) functions as a competitive inhibitor of urease, with an IC50 value of 3.51 μM and a Ki of 3.11 μM. It is applicable for research pertaining to peptic and gastric ulcers [1]. | |||
T38058 | Cimetidine sulfoxide | ||
Cimetidine sulfoxide (Cimetidine sulphoxide) is a sulfoxide metabolite of Cimetidine. Cimetidine is a histamine H2-receptor antagonist. Cimetidine has the potential for peptic ulcer disease and upper gastrointestinal hae... | |||
T70428 | Nepaprazole sodium | ||
Nepaprazole Na is the salt form of Nepaprazole Free Base, also known as TY-11345, is a proton pump inhibitor potentially for treatment of gastric ulcer. TY-11345 potently inhibited H+/K(+)-ATPase activity in isolated ra... | |||
T79652 | Urease-IN-7 | ||
Urease-IN-7 (Compound 5k) acts as a competitive inhibitor of the enzyme urease, exhibiting an IC50 value of 3.33 μM and a K_i of 3.62 μM. This compound has potential applications in the study of peptic and gastric ulcers... | |||
T36714 | Sucrose octasulfate (potassium salt) | ||
Sucrose octasulfate (SOS), a component of the gastrointestinal protectant sucralfate, is an alkaline aluminum-sucrose complex that inhibits peptic hydrolysis and raises gastric pH, protecting esophageal epithelium agains... | |||
T61643 | Vonoprazan hydrochloride | ||
Vonoprazan hydrochloride, a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan hydrochloride inhibits H +,K + -ATPase activity i... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3605 | Gastrodenol | Bismuth tripotassium dicitrate,Bismuth subcitrate | Others |
Gastrodenol (Bismuth tripotassium dicitrate) is a bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease. | |||
T7908 | DL-Methionine Methylsulfonium Chloride | Others | |
DL-Methionine Methylsulfonium Chloride is a natural product, used in the treatment of peptic ulcers, colitis, and gastritis. | |||
T21651 | Lansoprazole sodium | Lansoprazole (sodium), AG-1749 sodium | Proton pump , Phospholipase , Antibacterial |
Lansoprazole sodium (Lansoprazole (sodium)) is a proton pump inhibitor (PPI) and a potent inhibitor of gastric acidity which is widely used in the therapy of gastroesophageal reflux and peptic ulcer disease. | |||
T2745 | 18α-Glycyrrhetinic acid | Enoxolone,Glycyrrhetinic acid | Apoptosis , NF-κB , Proteasome |
18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb licorice. It is used in flavoring a... | |||
TN1302 | 6,8-Diprenylorobol | Others , HIV Protease , Antifection | |
6,8-Diprenylorobol possesses weaker anti-H. pylori activity, it may be a useful chemopreventive agent for peptic ulcer or gastric cancer in H. pylori-infected individuals. | |||
TN3852 | Dihydrolicoisoflavone | Antifection | |
Dihydrolicoisoflavone A possesses weaker anti-H. pylori activity, it may be useful chemopreventive agents for peptic ulcer or gastric cancer in H. pylori-infected individuals. | |||
TN4659 | Nimbin | COX | |
Nimbin is an anti-pyretic, can be used to treat arthritis, hypoglycaemia, peptic ulcers, anti-secretory activity, and it can also be used as an antibiotic. Nimbin requires to elicit a 50% inhibition of this steroid hydro... |