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Search Results for " peptic "

Targets

43

Compounds

7

Natural Products

Cat No. Product Name Synonyms Targets
T5051 Isopropamide Iodide AChR
Isopropamide iodide is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders. It also acts as a muscarinic receptor antagonist which can be applied to the t...
T38612 Linaprazan glurate Others
Linaprazan glurate inhibits exogenously or endogenously stimulated gastric acid secretion. Linaprazan glurate can be used in studies about gastrointestinal inflammatory diseases and peptic ulcer diseases.
T4981 Anisotropine Methylbromide Prostaglandin Receptor , AChR
Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion.
T15500 HPi1 Others , Antibacterial
HPi1 is a selective and orally active antimicrobial against Helicobacter pylori (IC50: 0.24 μM and a MIC of 0.08-0.16 μg/mL). HPi1 is inactive against other Xaliproden, including the gut commensals, Lactobacillus reuteri...
T0044 Oxethazaine Oxetacaine HBV , Sodium Channel
Oxethazaine (Oxetacaine), a topical anesthetic, is used to prevent acid-induced esophageal pain.
T1734 Rabeprazole Sulfide Rabeprazole Related Compound E Proton pump , Antibacterial
Rabeprazole Sulfide (Rabeprazole Related Compound E) is an antiulcer drug in the class of proton pump inhibitors.
T0992 Carbenoxolone disodium Biogastrone,Duogastrone,Bioral Gap Junction Protein
Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise, ...
T8388 Vonoprazan TAK-438 (free base) Proton pump
Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis
T21254 Vonoprazan Fumarate TAK-438,TAK 438,Vonoprazan Fumurate,TAK438 Proton pump
Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion. Vonoprazan Fumarate (TAK438) inhibited H+,K+-ATPase activity in porcine gastric microsomes with IC50 value of 19...
T25939 Pepticinnamin E
Pepticinnamin E is a naturally occurring bisubstrate farnesyltransferase inhibitor.
T29015 Trithiozine Tresanil,Sulmetozine,Tritiozinum,Tritiozine,Tritiozina Others
Trithiozine (Tritiozinum) exhibits antisecretory and antiulcer capacity. Trithiozine can be used for research on the treatment of peptic ulcer disease and hypersecretory disorders.
T25737 Linetastine TMK 688,TMK-688,TMK688 Lipoxygenase , LTR , Histamine Receptor
Linetastine (TMK-688) is a 5-lipoxygenase inhibitor (5-LOX) that inhibits leukotriene production and antagonizes the effects of histamine.Linetastine is used in studies of asthma, atherosclerosis, and peptic ulcers.
T0246L Betahistine mesylate Extovyl,Melopat,Meginalisk Histamine Receptor
Betahistine mesylate (Extovyl) is a histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers.
T10221 Abeprazan hydrochloride DWP14012 hydrochloride,Fexuprazan hydrochloride Proton pump
Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPase by competitive binding to potassium ions without acid activat...
T4195 Betahistine PT 9 base,Vasomotal,Serc base Histamine Receptor
Betahistine (Vasomotal) is a histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers. Betahisti...
T0786 Clidinium bromide Ro 2-3773 AChR
Clidinium bromide (Ro 2-3773) , a synthetic anticholinergic agent, has been shown in experimental and clinical researchers to have a pronounced antisecretory and antispasmodic effect on the gastrointestinal tract. It can...
T27640 Itriglumide CR-2945,CR2945,CR 2945
Itriglumide, a CCK2 receptor antagonist, is used potentially for the treatment of peptic ulcers, dyspepsia, and gastroesophageal reflux disease (GERD).
T31743 Famotine hydrochloride Famotine HCl,UK-2054
Famotine Hydrochloride is a histamine H2 receptor antagonist that suppresses acid production in the stomach and commonly treats peptic ulcer disease and gastroesophageal reflux disease.
T32224 Isopropamide Priazimide,Dipramide,Piaccamide,Chloroisopropamide,Dipramid
Isopropamide (R5) is a long-acting anticholinergic drug. It is used to treat peptic ulcers and other gastrointestinal disorders involving excess gastric acid (gastrointestinal acidosis) and hyperactivity.
T34936 Tridihexethyl chloride Propethonum,Pathilon,Tridihexethyl
Tridihexethyl is an anticholinergic, antimuscarinic, and antispasmolytic drug, which can be used to treat acquired nystagmus or peptic ulcer disease.
T14051 5-Hydroxylansoprazole AG1908 Proton pump
5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole, a gastric proton-pump inhibitor that effectively treats various peptic diseases[1][2]. The metabolism of Lansoprazole occurs through CYP2C19, result...
T68206 Arbortristoside A
Arbortristoside A is an anti-inflammatory and antinociceptive. This activity may be due to the inhibiting effect of prostaglandin, histamine and serotonin. Arbortristoside A has also been shown to act on ulcerations and ...
T70127 Famotine
Famotine is a histamine H2 receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease.
T2138L Oxyphencyclimine Oxiphencycliminum,Antulcus,Zamanil,Manir,Caridan,Naridan
Oxyphencyclimine is a muscarinic receptor antagonist (MRA) anticholinergic drug used to treat peptic ulcers.
T70090 Nizatidine amide
Nizatidine amide is a histamine H2 receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease.
T68725 Famotidine propanamide
Famotidine propanamide is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease.
T12914 Siltenzepine Others
Siltenzepine is an agent of anti-acid agent,and used in the treatment of peptic ulcers.
T71801 Arbaprostil
Arbaprostil is a synthetic prostaglandin E analog that protects gastric mucosa, prevents ulceration, and promotes healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inh...
T19929 Ranitidine-S-oxide
Ranitidine-S-oxide is a metabolite of Ranitidine. It is commonly used in the treatment of peptic ulcer disease, Zollinger–Ellison syndrome,and gastroesophageal reflux disease.
T61228 Pirenzepine
Pirenzepine (LS 519 free base) is a selective antagonist of the M1 muscarinic acetylcholine receptor (mAChR). It effectively inhibits gastric acid secretion and reduces muscle spasm, making it a valuable compound for inv...
T71509 Famotidine sulfamoyl propanamide
Famotidine sulfamoyl propanamide is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease.
T71485 Famotidine propionic acid
Famotidine propionic acid is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease.
T71049 Famotidine disulfide
Famotidine disulfide is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease.
T71980 Omeprazole acid
Omeprazole acid is a medication used in the treatment of gastroesophageal reflux disease, peptic ulcer disease, and Zollinger–Ellison syndrome. It is also used to prevent upper gastrointestinal bleeding in people who are...
T33314 Methantheline Bromide Frenogastrico,Dixamone bromide,Banthine,Asabaine,Methanthelinium bromide
Methantheline Bromide is a synthetic spasmolytic used to relieve cramps or spasms of the stomach, bowel, and bladder. It is also useful for intestinal or gastric ulcers (peptic ulcer disease), intestinal problems, pancre...
T25104 Aprofene aprophen,Aprofenum
Aprofene (Aprophen) is an antagonist of muscarinic and nicotinic acetylcholine receptors. It may be used in the therapy of peptic ulcers, endarteritis (inflammation of the inner shell of the artery), cholecystitis (infla...
T78237 Urease-IN-6
Urease-IN-6, a potent Urease inhibitor, exhibits an IC50 value of 14.2 μM and is utilized in the research of peptic and gastric ulcers [1].
T79656 Urease-IN-8
Urease-IN-8 (Compound 5e) functions as a competitive inhibitor of urease, with an IC50 value of 3.51 μM and a Ki of 3.11 μM. It is applicable for research pertaining to peptic and gastric ulcers [1].
T38058 Cimetidine sulfoxide
Cimetidine sulfoxide (Cimetidine sulphoxide) is a sulfoxide metabolite of Cimetidine. Cimetidine is a histamine H2-receptor antagonist. Cimetidine has the potential for peptic ulcer disease and upper gastrointestinal hae...
T70428 Nepaprazole sodium
Nepaprazole Na is the salt form of Nepaprazole Free Base, also known as TY-11345, is a proton pump inhibitor potentially for treatment of gastric ulcer. TY-11345 potently inhibited H+/K(+)-ATPase activity in isolated ra...
T79652 Urease-IN-7
Urease-IN-7 (Compound 5k) acts as a competitive inhibitor of the enzyme urease, exhibiting an IC50 value of 3.33 μM and a K_i of 3.62 μM. This compound has potential applications in the study of peptic and gastric ulcers...
T36714 Sucrose octasulfate (potassium salt)
Sucrose octasulfate (SOS), a component of the gastrointestinal protectant sucralfate, is an alkaline aluminum-sucrose complex that inhibits peptic hydrolysis and raises gastric pH, protecting esophageal epithelium agains...
T61643 Vonoprazan hydrochloride
Vonoprazan hydrochloride, a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan hydrochloride inhibits H +,K + -ATPase activity i...

Compounds

Isopropamide Iodide
T5051
Synonym:
Target: AChR
Linaprazan glurate
T38612
Synonym:
Target: Others
Anisotropine Methylbromide
T4981
Synonym:
Target: Prostaglandin Receptor, AChR
HPi1
T15500
Synonym:
Target: Others, Antibacterial
Oxethazaine
T0044
Synonym: Oxetacaine
Target: HBV, Sodium Channel
Rabeprazole Sulfide
T1734
Synonym: Rabeprazole Related Compound E
Target: Proton pump, Antibacterial
Carbenoxolone disodium
T0992
Synonym: Biogastrone,Duogastrone,Bioral
Target: Gap Junction Protein
Vonoprazan
T8388
Synonym: TAK-438 (free base)
Target: Proton pump
Vonoprazan Fumarate
T21254
Synonym: TAK-438,TAK 438,Vonoprazan Fumurate,TAK438
Target: Proton pump
Pepticinnamin E
T25939
Synonym:
Target:
Trithiozine
T29015
Synonym: Tresanil,Sulmetozine,Tritiozinum,Tritiozine,Tritiozina
Target: Others
Linetastine
T25737
Synonym: TMK 688,TMK-688,TMK688
Target: Lipoxygenase, LTR, Histamine Receptor
Betahistine mesylate
T0246L
Synonym: Extovyl,Melopat,Meginalisk
Target: Histamine Receptor
Abeprazan hydrochloride
T10221
Synonym: DWP14012 hydrochloride,Fexuprazan hydrochloride
Target: Proton pump
Betahistine
T4195
Synonym: PT 9 base,Vasomotal,Serc base
Target: Histamine Receptor
Clidinium bromide
T0786
Synonym: Ro 2-3773
Target: AChR
Itriglumide
T27640
Synonym: CR-2945,CR2945,CR 2945
Target:
Famotine hydrochloride
T31743
Synonym: Famotine HCl,UK-2054
Target:
Isopropamide
T32224
Synonym: Priazimide,Dipramide,Piaccamide,Chloroisopropamide,Dipramid
Target:
Tridihexethyl chloride
T34936
Synonym: Propethonum,Pathilon,Tridihexethyl
Target:
5-Hydroxylansoprazole
T14051
Synonym: AG1908
Target: Proton pump
Arbortristoside A
T68206
Synonym:
Target:
Famotine
T70127
Synonym:
Target:
Oxyphencyclimine
T2138L
Synonym: Oxiphencycliminum,Antulcus,Zamanil,Manir,Caridan,Naridan
Target:
Nizatidine amide
T70090
Synonym:
Target:
Famotidine propanamide
T68725
Synonym:
Target:
Siltenzepine
T12914
Synonym:
Target: Others
Arbaprostil
T71801
Synonym:
Target:
Ranitidine-S-oxide
T19929
Synonym:
Target:
Pirenzepine
T61228
Synonym:
Target:
Famotidine sulfamoyl propanamide
T71509
Synonym:
Target:
Famotidine propionic acid
T71485
Synonym:
Target:
Famotidine disulfide
T71049
Synonym:
Target:
Omeprazole acid
T71980
Synonym:
Target:
Methantheline Bromide
T33314
Synonym: Frenogastrico,Dixamone bromide,Banthine,Asabaine,Methanthelinium bromide
Target:
Aprofene
T25104
Synonym: aprophen,Aprofenum
Target:
Urease-IN-6
T78237
Synonym:
Target:
Urease-IN-8
T79656
Synonym:
Target:
Cimetidine sulfoxide
T38058
Synonym:
Target:
Nepaprazole sodium
T70428
Synonym:
Target:
Urease-IN-7
T79652
Synonym:
Target:
Sucrose octasulfate (potassium salt)
T36714
Synonym:
Target:
Vonoprazan hydrochloride
T61643
Synonym:
Target:
Cat No. Product Name Synonyms Targets
T3605 Gastrodenol Bismuth tripotassium dicitrate,Bismuth subcitrate Others
Gastrodenol (Bismuth tripotassium dicitrate) is a bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease.
T7908 DL-Methionine Methylsulfonium Chloride Others
DL-Methionine Methylsulfonium Chloride is a natural product, used in the treatment of peptic ulcers, colitis, and gastritis.
T21651 Lansoprazole sodium Lansoprazole (sodium), AG-1749 sodium Proton pump , Phospholipase , Antibacterial
Lansoprazole sodium (Lansoprazole (sodium)) is a proton pump inhibitor (PPI) and a potent inhibitor of gastric acidity which is widely used in the therapy of gastroesophageal reflux and peptic ulcer disease.
T2745 18α-Glycyrrhetinic acid Enoxolone,Glycyrrhetinic acid Apoptosis , NF-κB , Proteasome
18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb licorice. It is used in flavoring a...
TN1302 6,8-Diprenylorobol Others , HIV Protease , Antifection
6,8-Diprenylorobol possesses weaker anti-H. pylori activity, it may be a useful chemopreventive agent for peptic ulcer or gastric cancer in H. pylori-infected individuals.
TN3852 Dihydrolicoisoflavone Antifection
Dihydrolicoisoflavone A possesses weaker anti-H. pylori activity, it may be useful chemopreventive agents for peptic ulcer or gastric cancer in H. pylori-infected individuals.
TN4659 Nimbin COX
Nimbin is an anti-pyretic, can be used to treat arthritis, hypoglycaemia, peptic ulcers, anti-secretory activity, and it can also be used as an antibiotic. Nimbin requires to elicit a 50% inhibition of this steroid hydro...
TargetMol