organophosphate

Azamethiphos, an organothiophosphate insecticide, is used in Atlantic salmon fish farming to control parasites.

Cyclopentolate Hydrochloride is a muscarinic acetylcholine receptors antagonist with Kis of 1.62, 27.5, and 2.63 nM for M1, M2, and M3 receptors, respectively.

Anisodamine (6-beta-Hydroxyhyoscyamine) is an antagonist of muscarinic and nicotinic cholinoceptor with similar affinities at the muscarinic receptor as scopolamine and atropine. Anisodamine improve the microcirculation in states of shock and can be used in studies about organophosphate poisoning.

Diazinon (Dimpylate) is a thiophosphoric acid ester, functioning as a nonsystemic organophosphate insecticide that effectively targets and controls a variety of pests including cockroaches, silverfish, ants, and fleas.

Pralidoxime Chloride (2-PAM chloride) is a useful agent in the treatment of organophosphate poisoning. Pralidoxime binds to organophosphate-inactivated acetylcholinesterase, used to combat poisoning by organophosphates or acetylcholinesterase inhibitors (nerve agents).

TDCPP (Fyrol FR 2) is classified under the chlorinated trialkyl organophosphate flame retardant (OPFR) group of compounds primarily utilized as additives in commercial products.

Isazofos is a broad-spectrum organophosphate insecticide and nematicide effective in controlling a variety of lawn pests, such as nematodes (Radopholus similis). It also demonstrates efficacy in managing rice gall midge.

Tricresyl phosphate is an organophosphate compound. It is used as a plasticizer and diverse other applications.

Tetrachlorvinphos, an organophosphate cholinesterase inhibitor, is used as an insecticide. It has low toxicity to mammals.

Propetamphos, an organophosphate pesticide, can effectively control cockroaches, flies, mosquitoes, and other pests. It is also effective for cattle lice.

Tri(2-butoxyethyl) phosphate (Phosflex T-bep), a plastic plasticizer and flame retardant, is an organophosphate derived from milk powder.

Pralidoxime Iodide, also named 2-PAM, is an antidote approved for reactivation of inhibited acetylcholinesterase (AChE) in organophosphate poisoning.

Piperophos is an organophosphate with anti-androgenic activities.

Aspon is an organophosphate pesticide, it is used primarily on turf insects.

Phosmet oxon is a toxic metabolite of phosmet, a phthalimide-derived, non-systemic, organophosphate insecticide used on plants and animals. It is mainly used on apple trees for control of codling moth, though it is also used on a wide range of fruit crops

Phoxim is an organophosphate insecticide that inhibits acetylcholinesterase (AchE) activity in the nervous system of insects. It is used in veterinary medicine for the treatment of ectoparasitic mites. It is toxic to aquatic organisms and may affect cytochrome P450 enzyme (CYP1A) activity and its expression levels in fish liver microsomes. In addition, sub-lethal doses of phoxim affected detoxification enzyme activities of adult mulberry whitefly, such as changes in the activities of glutathione S-transferase (GST), carboxylesterase (CarE) and acetylcholinesterase (AchE).

Profenofos is a broad-spectrum organophosphate insecticide used primarily for pest and mite control in cotton and vegetables. Profenofos causes neurotoxicity in insects and mites by interfering with nerve signaling through the inhibition of acetylcholinesterase (AChE) activity.Profenofos is relatively stable in the environment but breaks down rapidly under alkaline conditions.

Phosalone is an organophosphate chemical commonly used as an insecticide and acaricide.

K027 is a potent organophosphate (OP) inhibitor of acetylcholinesterase (AChE) reactivation. k027 can be used to study Alzheimer's disease.

Diazoxon is the oxidized form of Diazinon -- an organophosphate insecticide. Diazoxon is shown to be a more potent acetylcholinesterase (AChE) inhibitor.

Pralidoxime is a potent antidote for organophosphate poisoning, effectively reactivating acetylcholinesterase (AChE) that has been inhibited by nerve agents. It achieves this reactivation through a direct nucleophilic attack of its oxime moiety on the phosphorus center of the bound nerve agent, restoring AChE function.

Metrifonate is an organophosphorus prodrug that is metabolised non-enzymatically in the body to DDVP (dichlorvos), which acts as an irreversible cholinesterase (ChE) inhibitor. It inactivates ChE by phosphorylating the serine residue at its active site, making it useful for treating Alzheimer's disease and as an insecticide. Metrifonate affects AChE activity, oxidative stress, neurotoxicity, and cortisol levels in carp.

Malathion-d10 is a deuterated compound of Malathion. Malathion has a CAS number of 121-75-5. Malathion is an organophosphate parasympathomimetic which binds irreversibly to cholinesterase, is an insecticide of relatively low human toxicity.

Malathion-d7 is a deuterated compound of Malathion. Malathion has a CAS number of 121-75-5. Malathion is an organophosphate parasympathomimetic which binds irreversibly to cholinesterase, is an insecticide of relatively low human toxicity.