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ogg1

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OGG1 Protein, Human, Recombinant (His)
OGH1, OGG1, N-glycosylase DNA lyase, MUTM, MMH
TMPH-01774
Expression system: E. coli
Length: 1-345, Full Length
Activity: Not Tested
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20 days
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Buffer-exchangeable
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OGG1 Protein, Human, Recombinant
OGH1, OGG1, N-Glycosylase DNA Lyase, MUTM, MMH, DNA-(Apurinic or Apyrimidinic Site) Lyase, AP Lyase, 8-Oxoguanine DNA Glycosylase
TMPJ-00457
Human N-Glycosylase DNA Lyase(OOG1) is a DNA repair enzyme, which belongs to the type-1 OGG1 family. OOG1 incises DNA at 8-oxoG residues, and excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damage DNA. It has a β-lyase activity that nicks DNA 3' to the lesion. OOG1 together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells. The OGG1 gene mutations may be caused Renal cell carcinoma.
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7-10 days
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