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(4)
By Target- Apoptosis
- Endothelin Receptor(2)
- Autophagy(1)
- CXCR(1)
- Caspase(1)
- IAP(1)
- Lipoxygenase(1)
- NF-κB(1)
- Neuropeptide Y Receptor(1)
- Others(1)
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Results for "
nonpeptid
" in TargetMol Product Catalog- Inhibitors & Agonists12
- Natural Products1
Eprosartan Mesylate
SKF-108566J
T2531144143-96-4
Eprosartan Mesylate (SKF-108566J) is a competitive and reversible Angiotensin II Receptor Blocker.
- $40
Size
QTY
BMS-202
Cited
PD1-PDL1 inhibitor 2, PD-1/PD-L1 inhibitor 2
T31461675203-84-5
BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction.
- $41
Size
QTY
CitedMacitentan
ACT-064992
T2561441798-33-0
Macitentan (ACT-064992) is an endothelin receptor antagonist utilized in the treatment of pulmonary arterial hypertension (PAH).
- $37
Size
QTY
AS057278
3-Methylpyrazole-5-carboxylic acid
T7476402-61-9
AS057278 (3-Methylpyrazole-5-carboxylic acid) is an D-amino acid oxidase (DAAO) inhibitor.
- $30
Size
QTY
Ivachtin
Caspase-3 Inhibitor VII
T11696745046-84-8
Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remaining caspases.
- $98
Size
QTY
LIT-001
T118572245072-21-1
LIT-001 improves social interaction in a mouse model of autism.It is the first nonpeptide oxytocin receptor agonist with EC50 of 55 nM and Ki of 226 nM.
- $52
Size
QTY
SCH79797 dihydrochloride
T128701216720-69-2
SCH79797 dihydrochloride is an effective and selective antagonist of protease activated receptor 1 (PAR1) with an IC50 of 70 nM and a Ki of 35 nM. SCH79797 dihydrochloride has antiproliferative and pro-apoptotic effects.
- $32
Size
QTY
SHA 68
T12895847553-89-3
SHA 68 is a potent and selective non-peptide antagonist of neuropeptide S receptor (NPSR) with IC50 values of 22.0 nM for NPSR Asn107 and 23.8 nM for NPSR Ile107.
- $36
Size
QTY
SB-265610
GSK-CXCR2
T16850211096-49-0
SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis (IC50s: 3.7 nM and 70 nM, respectively).
- $51
Size
QTY
RO 46-8443
T3474175556-12-4
RO 46-8443 is the first non-peptide endothelin ETB receptor selective antagonist. RO 46-8443 displays up to 2000-fold selectivity for ETB receptors both in terms of binding inhibitory potency and functional inhibition.
- $34
Size
QTY
Mozavaptan
OPC31260l, OPC-31260
T6288137975-06-5
Mozavaptan (OPC-31260) is a competitive antagonist of vasopressin receptors, targeting both V1 and V2 receptors, with IC50 values of 1.2 μM and 14 nM, respectively.
- $43
Size
QTY
Embelin Cited
NSC 91874, Emberine, Embelic acid
T6485550-24-3
Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).
- $33
Size
QTY
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