nematicidal

(R)-Monepantel ((R)-AAD1566) has potential anticancer activity but no nematicidal activity.

Amyl-2-Methylbutyrate (Pentyl 2-methylbutanoate) shows nematicidal activity against pine wood nematodes and can be used to study nematicides.

Fervenulin is isolated from a nematicidal actinomycete Streptomyces sp. CMU-MH021 with nematicidal activity. It also inhibits egg hatch and J2 mortality of M. incognita (MICs: 30 μg mL and 120 μg mL, respectively).

Nematicidal Agent 1 is an effective nematicide that binds to the pocket of acetylcholinesterase (AChE).

Cyprocide-B is activated by Cytochrome P450, which converts it into an electrophilic metabolite that selectively kills the nematode C. elegans. This compound holds promise for research into selective nematicidal agents.

5-Heneicosylresorcinol shows inhibitory effects on the release of β-hexosaminidase from RBL-2H3 cells, it also prevents triglyceride accumulation in 3T3-L1 cells. 5-Heneicosylresorcinol has nematicidal activity against nematodes Panagrellus redivivus, Cae

Roridin A (Roridine A), a compound isolated from Verruca sp., showed nematicidal activity against Meloidogyne incognita.Roridin A is cytotoxic and has immunomodulatory activity.Roridin A has been used in the study of adrenocortical hyperplasia (CAH) and Cushing's disease (CD).

Anagyrine, is the responsible teratogen from teratogenic lupins, can produce congenital deformities in calves typical of crooked calf disease; it also can induce red cell aplasia, vascular anomaly, and skeletal dysplasia.(-)-Anagyrine and (-)--Methylcytisine have nematicidal activities against Pine Wood Nematodes.

Neochamaejasmine B displays nematicidal activity against both Bursaphelenchus xylophilus and Bursaphelenchus mucronatus.

Omphalotin A, a cyclic peptide, exhibits nematicidal activity [1].

Camaric acid shows antibacterial activity against Staphylococcus aureus and methicillin resistant S. aureus with IC50 values 8.74 and 8.09 uM, respectively, it also shows moderate antileishmanial activity and highly potent antitrypanosomal activity. Camar

Conoidin A is a cell-permeable inhibitor of the T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. It covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC50 of 23 μM. It also inhibits hyperoxidation of mammalian PrxI and PrxII (but not PrxIII). Conoidin A has antioxidant, neuroprotective effects and can be used for research on ischaemic heart disease.

The compound cis-3-Indoleacrylic acid acts as a nematicidal agent and can be isolated from Streptomyces youssoufiensis YMF3.862. It functions as a V-ATPase inhibitor, reducing both the expression and enzymatic activity of V-ATPase. Additionally, cis-3-Indoleacrylic acid causes swelling in Meloidogyne incognita larvae and notable cracking on the cuticle surface [LC50: 16.31 μg mL]. It also inhibits the accumulation of H+ within nematodes.

8-Geranyloxypsoralen inhibits α2-secretase (BACE1) activity in non-competitive manner, with the IC(50) values <25.0 μM, it can induce vasorelaxation on rat arterial tissues. 8-Geranyloxypsoralen possesses nematicidal activities, the median lethal concentrations (LC(50)) is 188.3 mg L against B. xylophilus and is 117.5 mg L against P. redivivus.

1. Protostemonine has anti-inflammatory activity, it effectively attenuates LPS-induced inflammatory responses in vitro and in vivo; the beneficial effects are associated with the decreased phosphorylation of MAPK and AKT and the reduced expression of pro

Aspyrone is a polyketide fungal metabolite found in [Aspergillus] with diverse biological activities. It is active against 13 fungi at 20 μg ml and 21 bacteria at 100 μg per disc. Aspyrone (10-1,000 mg L) is nematocidal against [P. penetrans].

SDH-IN-23 (Compound B21) is an SDH inhibitor with exceptional nematicidal activity. It can suppress nematode feeding, reproduction, and embryonic development while also inducing lethal effects through mechanisms such as oxidative stress, intestinal damage, and SDH inhibition.

Isoschaftoside is used as an intercrop due to its allelopathic inhibition of parasitism by Striga hermonthica, an obligate parasitic weed that can devastate the maize crop. Isoschaftoside has anti-tumor, antioxidant, and antimicrobial activities, it also possesses strong nematicidal activity against M. incognita.

2-tridecanol (tridecan-2-ol) is a compound extracted from the Dufour gland secretions of worker ants and females, and shows strong direct contact nematicidal activity against Mycobacterium occidentalis J2s.

4-Ethylbenzaldehyde is a RIFM flavor present in naturally fermented tilapia sausage and soybean plants.4-Ethylbenzaldehyde shows nematicidal activity at 250 g ml and can be used as a novel nematicide.

Asperlactone is a nematicidal, insecticidal, antibacterial, and antifungal polyketide metabolite produced from A. westerdijkiae.