nad+

NAD+ (β-Nicotinamide Adenine Dinucleotide) is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH).

NAD+ (Standard) is a reference standard for research and analysis in studies involving NAD+. NAD+ (β-Nicotinamide Adenine Dinucleotide) is a coenzyme that transmits hydrogen ions and is involved in redox reactions in cells. NAD+ is involved in glycolysis, the citric acid cycle, fatty acid oxidation, etc. NAD+ accepts electrons from other molecules to form NADH, which then acts as a reducing agent to give electrons.

β-nicotinamide mononucleotide (NMN) is a natural nucleotide and a key intermediate in the synthesis of coenzyme I (NAD+). β-nicotinamide mononucleotide is involved in a number of biochemical reactions in the human body, which are related to immunity and metabolism.

Phytic acid dipotassium salt is an endogenous metabolite that inhibits β-secretase 1 (BACE1).

Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.

Nicotinamide riboside chloride, also known as NR and SRT647, is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+.

Syrosingopine is a dual inhibitor of MCT1 and MCT4, 60 times more potent against MCT4, preventing lactate and H+ efflux. Syrosingopine is an orally available antihypertensive drug with potential for cancer research in combination with metformin.

Resveratrol (SRT 501) is a polyphenolic natural product, a plant antitoxin with antioxidant and chemopreventive activities. Resveratrol has a wide range of targets including COX, SIRT, LOC, etc. Resveratrol induces autophagy and apoptosis.

Aucuparin (2,6-dimethoxy-4-phenylphenol) is a plant antibiotic with anti-inflammatory activity. Aucuparin inhibited pulmonary fibrosis in mouse models induced by bleomycin (BLM). ABTS and FRAP showed clear scavenging activity. Aucuparin inhibited superoxide production of human neutrophils induced by fmlp, and its IC50 was 17.0μM.

NADH disodium salt (Disodium NADH) hydrate is the reduced form of nicotinamide adenine dinucleotide (NAD) that can donate electrons in a reducing reaction, becoming oxidized to produce NAD+. Various enzymes utilize NADH disodium salt hydrate plus H+ to reduce substrates, generating NAD+ and the reduced product.

Menadione (Vitamin K3) is a synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.

Avermectin B1 is served as anthelmintic and insecticide.

Vitamin K1 (Phylloquinone) a fat-soluble, naturally occurring vitamin with antihemorrhagic and prothrombogenic activity.

NADP disodium salt (Disodium NADP) is a nicotinamide adenine dinucleotide. NADP disodium salt is a key redox cofactor for electron transfer in the metabolism, serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH).

Castor oil (Xenaderm) is a vegetable oil pressed from the seeds of the castor bean, Ricinus communis, used as a laxative and as an excipient in medicinally.

Eicosapentaenoic Acid is an ω-3 fatty acid and an inhibitor of fatty acid synthase (FASN). Eicosapentaenoic Acid promotes DNA demethylation in the reexpression of the tumor suppressor gene CCAAT/ enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates the RAS/ERK/C/EBPβ pathway in U937 leukemia cells through demethylation of the CpG island of H-RAS intron 1. Eicosapentaenoic Acid promotes the relaxation of vascular smooth muscle cells and vasodilation.

Apocynin (NSC 2146) is a specific NADPH-oxidase inhibitor (IC50: 10 μM).

NADP sodium salt (Sodium NADP) is a coenzyme that is widely distributed in living matter. Participates in oxidation-reduction reactions.

Rifamycin S is a potent DNA-dependent RNA polymerase inhibitor,is a quinone and an antibiotic agnet against Gram-positive bacteria

2-Methoxy-4-ethylphenol inhibits Flavin-containing monooxygenase 5 (NADPH oxidase) in human neutrophils and is widely used in biochemical experiments and drug synthesis research.

1-Nonadecanol is a saturated fatty alcohol. 1-Nonadecanol is one of the compositions of supercritical carbon dioxide (SC-CO2) essential oil of Heracleum thomsonii. 1-Nonadecanol is also an important aroma compound in Neotinea ustulata.

Dicoumarol (Dicumarol) is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicoumarol is a competitive inhibitor of vitamin K epoxidereductase; thus, it inhibits vitamin K recycling and causes depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes, and inhibits blood clotting.

2-Amino-3-carboxy-1,4-naphthoquinone is an electron transfer mediator that can alter glucose metabolism in homofermentative lactic acid bacteria. It also serves as a novel growth stimulator for bifidobacteria, influencing their end-product profile through the mediated oxidation of NAD(P)H.

Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemopreventive, and neuroprotective activities, it has protective effects against chronic diseases