Search Result

Search Results for " lymphocytes "

Targets

Compounds

Natural Products

589

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T8527	CPYPP		Others
	CPYPP is an inhibitor of DOCK2-Rac1 interaction. CPYPP binds to DOCK2 DHR-2 domain and inhibits the guanine nucleotide exchange factor (GEF) activity of DOCK2DHR-2 for Rac1 in a dose-dependent manner(IC50 : 22.8 µM). CPY...		Others
T3481	Bimolane		Topoisomerase
	Bimolane is a topoisomerase II inhibitor.		Topoisomerase
T6403	Siponimod	BAF-312	S1P Receptor , LPL Receptor
	BAF312 (Siponimod (BAF-312)), a next-generation S1P receptor modulator, is specific for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, respectively. The specificity of BAF312 for S1P1 and S1P5 receptors exhibi...		S1P Receptor , LPL Receptor
T23256	RS-25344 hydrochloride		PDE
	RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitor		PDE
T6588	Mitoxantrone	mitozantrone	Topoisomerase , PKC
	Mitoxantrone (mitozantrone) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisome...		Topoisomerase , PKC
T10765	Eragidomide	CC-90009,Cereblon modulator 1	Apoptosis , Ligand for E3 Ligase , Molecular Glues
	Eragidomide (CC-90009; Cereblon modulator 1) is a cereblon (CRBN) E3 ligase modulator. Eragidomide specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex.		Apoptosis , Ligand for E3 Ligase , Molecular Glues
T7739	L-Leucyl-L-Leucine methyl ester hydrochloride	Leu-Leu-ome hydrochloride	Others , Endogenous Metabolite
	L-Leucyl-L-Leucine methyl ester hydrochloride (Leu-Leu-ome hydrochloride) is a lysosomal condensation product that cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes.		Others , Endogenous Metabolite
T0158	Mitoxantrone dihydrochloride	Mitoxantrone 2HCl,Mitoxantrone hydrochloride,NSC-301739,mitozantrone dihydrochloride	Topoisomerase , PKC
	Mitoxantrone dihydrochloride (NSC-301739) is the hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. It is a type II topoisomerase inhibitor.		Topoisomerase , PKC
T6933	Peficitinib	ASP015K,JNJ-54781532	Tyrosine Kinases , JAK
	Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.		Tyrosine Kinases , JAK
T25705	Imupedone	LF1695,LF-1695,LF 1695	Others
	Imupedone (LF 1695) is a synthetic immunomodulator that modulates T lymphocytes and macrophages, induces T-cell differentiation of bone marrow precursor cells, and increases the proliferative response of lymphocytes to m...		Others
TP1758L	LCMV gp33-41 acetate	LCMV gp33-41 acetate（151705-84-9 Free base）	Others
	LCMV gp33-41 acetate is a sequence of lymphocytic choriomeningitis virus which restricted by major histocompatibility complex class I H-2Db and presented to cytotoxic T lymphocytes.		Others
T10565	BMS-1001 hydrochloride		PD-1/PD-L1
	BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activat...		PD-1/PD-L1
T26637	Antipain dihydrochloride	Antipain 2HCl,BDBM-32804,BDBM 32804, Antipain,BDBM32804	Protease
	Antipain dihydrochloride (Antipain 2HCl) is a protease inhibitor derived from Actinomycetes that exhibits analgesic activity and inhibits X-ray-induced chromosomal aberrations in human lymphocytes.		Protease
T28918	Talviraline	Bay 10-8979,HBY 097,Bay10-8979,Bay-108979,Bay108979,Bay 108979,Bay-10-8979	HIV Protease , DNA/RNA Synthesis
	Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in a variety of human cell lines, as well as in fresh human perip...		HIV Protease , DNA/RNA Synthesis
T16132	MRE3008F20		cAMP , Adenosine Receptor
	MRE3008F20 is a species-selective and potent adenosine A3 receptor (AA3R) antagonist that inhibits Cl-IB-MECA-induced cAMP production and can be used in glaucoma and asthma studies.CAS 번호13483-88-88-9		cAMP , Adenosine Receptor
T21443	Prednicarbate	Hoe 777,Hoe-777,Dermatop E emollient,UNII-V901LV1K7D	Others
	Prednicarbate (Hoe 777) is a Corticosteroid Hormone Receptor Agonist. Prednicarbate has antipruritic, anti-inflammatory, and vasoconstrictive properties. It also decreases the number of circulating lymphocytes by inhibit...		Others
T6964	Resiquimod	R848,S28463	HCV Protease , TLR
	Resiquimod (R848) is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through the TLR signaling pathway by binding to and acti...		HCV Protease , TLR
T6665	Sertaconazole nitrate	FI-7045,Ginedermofix,FI7056,Ertaczo	Antibiotic , Antifungal
	Sertaconazole nitrate (FI-7045), a topical broad-spectrum antifungal, is developed to supply an additional agent for the treatment of superficial cutaneous and mucosal infections.		Antibiotic , Antifungal
T9919	Alemtuzumab		Others
	Alemtuzumab is a humanized monoclonal antibody against CD52 an antigen found on the surface of normal and malignant lymphocytes.		Others
T36879L	H-Leu-Leu-OMe . HBr	H-Leu-Leu-OMe . HBr (16689-14-8 Free base)	Others
	H-Leu-Leu-OMe . HBr is a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes. H-Leu-Leu-OMe . HBr induces endolysosomal pathway stress and selectively eli...		Others
T4387	Evobrutinib	MSC2364447C,M2951	BTK
	Evobrutinib(M2951) , also known as M-2951 and MSC-2364447C, is a highly selective inhibitor of the Bruton's tyrosine kinase (BTK), which is important in the development and functioning of various immune cells including B...		BTK
T2171	SEW2871	SEW2871	S1P Receptor , LPL Receptor
	SEW 2871 is an orally available, highly selective S1P1 agonist with an EC50 of 13.8 nM.It reduces the number of lymphocytes in the blood and is used in studies related to diabetes, Alzheimer's disease, liver fibrosis, an...		S1P Receptor , LPL Receptor
TP1527	CEF8, Influenza Virus NP (383-391)	CEF8, Influenza Virus NP 383-391	Others
	CEF8, Influenza Virus NP (383-391) is an influenza A virus nucleoprotein containing residues 383 to 391, is the most important HLA-B*2705-restricted epitope in the nucleoprotein of influenza A viruses and is associated w...		Others
TP1543L	G280-9 acetate(156761-76-1 free base)		Others
	G280-9 acetate is a common melanoma gp100 epitope restricted by MHC-associated HLA-A2. The G280-9 sequence is unique because it could be recognized by cytotoxic T lymphocytes at very low concentrations, however it shows ...		Others
T24362	L 756423	L756423,MK-944a,MK944a,L-756,423,L-756423,MK 944a	HIV Protease
	L 756423 (L756423) is a novel potent and selective and competitive HIV protease inhibitor with a Ki value of 0.049 nM for HIV-1 PR.L 756423 blocks the spread of HIV(IIIb)-infected MT25 lymphocytes at 0.50-0.1 nM and can ...		HIV Protease
T4674	SB297006	SB 297006	CCR
	SB297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ. It is at least 250-fold selective for CCR3 over a panel of ...		CCR
T7055	Bz-RS-ISer(3-Ph)-Ome	Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate	Others , HIV Protease
	Bz-RS-ISer(3-Ph)-Ome (Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate) is a paclitaxel derivative that inhibits the HSV replication cycle at low cytotoxicity, blocks mitosis in Vero cells, affects the size o...		Others , HIV Protease
TQ0291	Firategrast	SB 683699	Integrin
	Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous system (CNS) and decreases multiple sclerosis (MS) activity...		Integrin
T2548	Diflorasone		Glucocorticoid Receptor
	Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by diffusion across the cell membrane and binds to the glucocorti...		Glucocorticoid Receptor
T11319	FR183998 free base		Na+/Ca2+ Exchanger
	FR183998 free base is an inhibitor of Na+/Ca2+ Exchanger.		Na+/Ca2+ Exchanger
T14909	CCX140	CCX140-B	CCR
	CCX140 (CCX140-B) (CCX140-B) is an antagonist of CCR2.		CCR
T28408	Phosphostim Sodium	IPH1101,Phosphostim,IPH 1101,IPH-1101
	Phosphostim, a gamma9deta2 T lymphocytes agonist, is used potentially for the treatment of renal cell carcinoma, HCV infection.
T30136	Armepavine hydrochloride, (+/-)-	DL-Armepavine hydrochloride
	Armepavine hydrochloride, (+/-)- is a compound which has been shown to exert immunosuppressive effects on T lymphocytes and on lupus nephritic mice.
T70307	POM2-C-HMBP
	POM2-C-HMBP is a potent Activator of Vγ9Vδ2 T-Lymphocytes. It is also an HMBPP ananlog prodrug.
T39145	4,6-Dichloroguaiacol
	4,6-Dichloroguaiacol elicits biochemical and morphological alterations in human peripheral blood lymphocytes in vitro.
T70889	Oxeclosporin
	Oxeclosporin is a hydroxyethyl derivative of serine(8)-cyclosporine; inhibits proliferation and functions of lymphocytes.
T31018	CP 115953	CP115953,Cp-115,953,CP-115953
	CP 115953 stimulated the production of cytokines by lymphocytes. CP 115953 inhibits the activity of topoisomerase II by interacting with the enzyme.
T69137	Oxophenarsine hydrochloride
	Oxophenarsine hydrochloride is a classical drug used to treat syphilis. Oxophenarsine HCl inhibits HIV-1-specific protein synthesis in acutely and persistently infected lymphocytes.
T28585	Ro 31-8588	Ro-31-8588
	Talviraline is a RNA-directed DNA polymerase inhibitor. HBY 097 is a highly potent inhibitor of HIV-1 replication and HIV-1 induced cell killing in a variety of human cell lines as well as in fresh human peripheral bloo...
T39014	KSPWFTTL
	KSPWFTTL is an immunodominant epitope derived from the p15E transmembrane protein. It is Kb-restricted and can enhance the susceptibility of a tumor cell line to cytotoxic T lymphocytes targeting anti-AKR/Gross MuLV.
TP1629	LCMV gp33-41 (TFA) (151705-84-9 free base)	LCMV gp33-41 (TFA)
	LCMV gp33-41 (TFA), the carboxyl-extended 11-aa-long peptide, is an lymphocytic choriomeningitis virus sequence restricted by MHC class I H-2Db molecules and presented to cytotoxic T lymphocytes[1].
T76835	Tositumomab
	Tositumomab, a murine IgG2a lambda monoclonal antibody, targets the CD20 antigen located on the surface of both normal and malignant B lymphocytes [1].
T17099	Timapiprant sodium	OC000459 sodium	Others
	Timapiprant sodium inhibits mast cell activation of Th2 lymphocytes and eosinophils. Timapiprant sodium is a potent and selective D prostanoid receptor 2 antagonist. Timapiprant sodium potently displaces [3H] PGD2 from h...		Others
T69723	Taminadenant mesylate
	Taminadenant, also known as PBF-509 and NIR-178, is a potent and orally active adenosine A2A receptor antagonist with potential antineoplastic activity. PBF-509 selectively binds to and inhibits A2AR expressed on T lym...
T82060	Interleukin-6 fragment (human)
	Interleukin-6 Fragment (human) is a pleiotropic cytokine originating from both lymphocytes and non-lymphocytes, encoded by a gene on human chromosome 7 spanning roughly 5 kilobases. This fragment shows promise for use in...
T27192	DMI-9523	DA-DKP,Ampion,DMI 9523,DM-9523
	DMI-9523 is nuclear factor NF-κB activation inhibitor. Antigen-stimulated human T lymphocytes produce significantly lower quantities of interferon-gamma and tumor necrosis factor-alpha after stimulation in vitro in the p...
T69830	GSK2239633
	GSK2239633 is a potent CC-chemokine receptor 4 antagonist with pIC50 of 7.9. The CC-chemokine receptor 4 (CCR4) is thought potentially to play a critical role in asthma pathogenesis due to its ability to recruit type 2...
T35906	Padanamide A
	Padanamide A is a bacterial metabolite originally isolated from a marine Streptomyces species. It is active against five strains of P. falciparum (EC50s = 160-340 nM), is not cytotoxic to HEK293 or HepG2 human cell lines...
T37288	Remisporine B
	Remisporine B is a polyketide and derivative of remisporine A that has been found inPenicilliumand has immunosuppressant activity.1,2It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymp...
T76755	Panobacumab
	Panobacumab (KBPA101) is a fully human IgM/κ monoclonal antibody developed through the immortalization of human B lymphocytes targeted against the LPS O polysaccharide of P. aeruginosa serotype O11 [1].

Compounds

Target: Topoisomerase

Siponimod

T6403

Synonym: BAF-312

Target: S1P Receptor, LPL Receptor

RS-25344 hydrochloride

Synonym: mitozantrone

Target: Topoisomerase, PKC

Eragidomide

T10765

Synonym: CC-90009,Cereblon modulator 1

Target: Apoptosis, Ligand for E3 Ligase, Molecular Glues

L-Leucyl-L-Leucine methyl ester hydrochloride

T7739

Synonym: Leu-Leu-ome hydrochloride

Target: Others, Endogenous Metabolite

Mitoxantrone dihydrochloride

T0158

Synonym: Mitoxantrone 2HCl,Mitoxantrone hydrochloride,NSC-301739,mitozantrone dihydrochloride

Target: Topoisomerase, PKC

Peficitinib

T6933

Synonym: ASP015K,JNJ-54781532

Target: Tyrosine Kinases, JAK

Imupedone

T25705

Synonym: LF1695,LF-1695,LF 1695

Target: Others

LCMV gp33-41 acetate

TP1758L

Synonym: LCMV gp33-41 acetate（151705-84-9 Free base）

Target: Others

BMS-1001 hydrochloride

T10565

Synonym:

Target: PD-1/PD-L1

Antipain dihydrochloride

T26637

Synonym: Antipain 2HCl,BDBM-32804,BDBM 32804, Antipain,BDBM32804

Target: Protease

Talviraline

T28918

Synonym: Bay 10-8979,HBY 097,Bay10-8979,Bay-108979,Bay108979,Bay 108979,Bay-10-8979

Target: HIV Protease, DNA/RNA Synthesis

MRE3008F20

T16132

Synonym:

Target: cAMP, Adenosine Receptor

Prednicarbate

T21443

Synonym: Hoe 777,Hoe-777,Dermatop E emollient,UNII-V901LV1K7D

Target: HCV Protease, TLR

Sertaconazole nitrate

T6665

Synonym: FI-7045,Ginedermofix,FI7056,Ertaczo

Target: Antibiotic, Antifungal

Synonym: H-Leu-Leu-OMe . HBr (16689-14-8 Free base)

Target: Others

evobrutinib

T4387

Synonym: MSC2364447C,M2951

Target: S1P Receptor, LPL Receptor

CEF8, Influenza Virus NP (383-391)

TP1527

Synonym: CEF8, Influenza Virus NP 383-391

Target: Others

G280-9 acetate(156761-76-1 free base)

Synonym: L756423,MK-944a,MK944a,L-756,423,L-756423,MK 944a

Synonym: Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate

Target: Others, HIV Protease

Target: Glucocorticoid Receptor

FR183998 free base

T11319

Synonym:

Target: Na+/Ca2+ Exchanger

Synonym: IPH1101,Phosphostim,IPH 1101,IPH-1101

Target:

Armepavine hydrochloride, (+/-)-

T30136

Synonym: DL-Armepavine hydrochloride

Synonym: CP115953,Cp-115,953,CP-115953

Target:

Oxophenarsine hydrochloride

LCMV gp33-41 (TFA) (151705-84-9 free base)

TP1629

Synonym: LCMV gp33-41 (TFA)

Synonym: OC000459 sodium

Target: Others

Taminadenant mesylate

T69723

Synonym:

Target:

Interleukin-6 fragment (human)

Synonym: DA-DKP,Ampion,DMI 9523,DM-9523

Cat No.	Product Name	Synonyms	Targets
TN1697	Glucosyringic acid		Immunology/Inflammation related
	Glucosyringic acid has immunosuppressive effect, it can inhibit the proliferation of murine B lymphocytes in vitro.		Immunology/Inflammation related
T7924	8-Bromoguanosine		Others
	8-Bromoguanosine is a brominated derivative of guanosine. It is activate lymphocytes through an intracellular mechanism to exert immunostimulatory effects.		Others
T5S0777	Phellodendrine chloride		Others
	Phellodendrine chloride has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli.		Others
T6S0781	Phellodendrine	Phallodendrin	Others , NF-κB , Akt
	1. Phellodendrine (Phallodendrin) has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli.		Others , NF-κB , Akt
T37705	1,2,4-Trihydroxybenzene	Benzene-1,2,4-triol	Calcium Channel
	1,2,4-Trihydroxybenzene (Benzene-1,2,4-triol) is a by-product of coffee bean roasting and is found in mouse, arabica coffee.1,2,4-Trihydroxybenzene is a benzotriol that increases Ca2+ concentration in rat thymic lymphocy...		Calcium Channel
T0798	Triamcinolone	Fluoxyprednisolone,Aristocort,Rodinolone	Glucocorticoid Receptor , COX
	Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, triamcinolone binds to and activates the glucocorticoid receptor, which leads to transloca...		Glucocorticoid Receptor , COX
T20879	Tacrolimus monohydrate	FK-506,FR 900506,Prograf,FR900506,Tacrolimus hydrate,LCP-Tacro,FK 506	Phosphatase , Others , Antibacterial , Antibiotic , Autophagy
	Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, whi...
T4S1943	Kirenol	Kirel	Wnt/beta-catenin
	1. Kirenol (Kirel) has anti-oxidant, anti-inflammatory, anti-allergic, and anti-arthritic activities. 2. Kirenol is effective against gram-positive bacteria. 3. Kirenol possesses antitumor action on human chronic myeloid...		Wnt/beta-catenin
TN1861	Licoflavone C	4',5,7-Trihydroxy-8-prenylflavone	Antioxidant , Antifungal
	Licoflavone C (4',5,7-Trihydroxy-8-prenylflavone) is an isoprenoid-based flavonoid compound isolated from the roots of Glycyrrhiza inflata, which possesses antioxidant and antifungal activities, and is known to have a pr...		Antioxidant , Antifungal
T2563	Acetyl-L-carnitine hydrochloride	Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride	Others , Endogenous Metabolite
	Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) is a nutritional supplement composed of the hydrochloride salt form of the acetylated form of the endogenously produced L-carnitine, with potential neur...		Others , Endogenous Metabolite
T13969L	Xanthopterin	Ksantopterin	Others
	Xanthopterin could inhibit the growth of lymphocytes produced by concanavalin.		Others
T70221	Dibefurin
	Dibefurin is a metabolite that inhibits the activity of calcineurin, a calcium/calmodulin-dependent protein phosphatase involved in the activation of T lymphocytes.
T16160	Musk tibetene	Musk tibetine	Others
	Musk tibetine reveals no genotoxicity in the micronucleus test with human lymphocytes and human hepatoma cell lines. Musk tibetene is a nitro musk compound with carcinogenic activity.		Others
T75502	Brazilein
	Brazilein, an immunosuppressive compound extracted from Caesalpinia sappan L., effectively induces apoptosis in mouse spleen lymphocytes [1].
TN5138	Teuclatriol		TNF , NF-κB , TLR
	Teuclatriol was found to be one of the compounds responsible for the immunoinhibitory effect of Salvia mirzayanii, by inhibiting NF-ÎºB signaling at doses of 312µM and higher. It showed a significant anti-proliferative e...		TNF , NF-κB , TLR
T75692	Hypoglaunine D
	Hypoglaunine D, an analogue of Triptonine B, serves as an anti-HIV compound by inhibiting HIV replication in H9 lymphocytes, demonstrating an efficacy with an EC50 value of 22 μg/ml [1].
TN3152	6-Acetonyldihydrochelerythrine		ERK , BCL , Akt , HIV Protease , PPAR , p53
	6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therapeutic Index) values of 1.77 microg/mL and 14.6, respectively...		ERK , BCL , Akt , HIV Protease , PPAR , p53
TN4084	Fumitremorgin B		Antifection
	Fumitremorgen B is a mycotoxin, it exhibits a certain degree of genotoxicity, it can cause DNA damage in human lymphocytes; it shows an inhibitory activity on the cell cycle progression of mouse tsFT210 cells in the M ph...		Antifection

Natural Products

Glucosyringic acid

TN1697

Synonym:

Target: Immunology/Inflammation related

Phellodendrine chloride

Synonym: Phallodendrin

Target: Others, NF-κB, Akt

1,2,4-Trihydroxybenzene

T37705

Synonym: Benzene-1,2,4-triol

Target: Calcium Channel

Triamcinolone

T0798

Synonym: Fluoxyprednisolone,Aristocort,Rodinolone

Target: Glucocorticoid Receptor, COX

Tacrolimus monohydrate

T20879

Synonym: FK-506,FR 900506,Prograf,FR900506,Tacrolimus hydrate,LCP-Tacro,FK 506

Target: Phosphatase, Others, Antibacterial, Antibiotic, Autophagy

Kirenol

T4S1943

Synonym: Kirel

Target: Wnt/beta-catenin

Licoflavone C

TN1861

Synonym: 4',5,7-Trihydroxy-8-prenylflavone

Target: Antioxidant, Antifungal

Acetyl-L-carnitine hydrochloride

T2563

Synonym: Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride

Target: Others, Endogenous Metabolite

Xanthopterin

T13969L

Synonym: Ksantopterin

Synonym: Musk tibetine

Target: TNF, NF-κB, TLR

6-Acetonyldihydrochelerythrine

TN3152

Synonym:

Target: ERK, BCL, Akt, HIV Protease, PPAR, p53

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04578	Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His)	Human	Yeast
	IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, par...
TMPY-01255	CD2 Protein, Human, Recombinant (His)	Human	HEK293
	T-cell surface antigen CD2, also known as T-cell surface antigen T11/Leu-5, and SRBC, is a single-pass type I membrane protein. It contains one Ig-like C2-type domain and one Ig-like V-type domain. CD2 is a cell adhesion...
TMPY-00860	CD122/IL2RB Protein, Human, Recombinant	Human	HEK293
	Interleukin-2 receptor (IL-2R) also known as High-affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, and IL-2RB, is involved in T cell-mediated immune responses. CD122/IL-2RB is present in 3 forms concernin...
TMPY-05102	CD122/IL2RB Protein, Rat, Recombinant (His)	Rat	HEK293
	Interleukin-2 receptor (IL-2R) also known as High-affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, and IL-2RB, is involved in T cell-mediated immune responses. CD122/IL-2RB is present in 3 forms concernin...
TMPY-05047	CD44 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CD44 is a type I transmembrane protein and a member of the cartilage link protein family. It is involved in cell-cell and cell-matrix interactions and signal transduction. Several CD44 ligands have been identified. The m...
TMPY-01068	CD70 Protein, Human, Recombinant (hFc)	Human	HEK293
	CD70, a member of the tumor necrosis factor superfamily, is restricted to activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor, CD27, is important in priming, effector functions, diff...
TMPY-04717	CD122/IL2RB Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	Interleukin-2 receptor (IL-2R) also known as High-affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, and IL-2RB, is involved in T cell-mediated immune responses. CD122/IL-2RB is present in 3 forms concernin...
TMPY-02033	CD44 Protein, Human, Recombinant (His)	Human	HEK293
	CD44 is a type I transmembrane protein and a member of the cartilage link protein family. It is involved in cell-cell and cell-matrix interactions and signal transduction. Several CD44 ligands have been identified. The m...
TMPY-05216	CD122/IL2RB Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Interleukin-2 receptor (IL-2R) also known as High-affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, and IL-2RB, is involved in T cell-mediated immune responses. CD122/IL-2RB is present in 3 forms concernin...
TMPY-05680	CD122/IL2RB Protein, Human, Recombinant (mFc)	Human	HEK293
	Interleukin-2 receptor (IL-2R) also known as High-affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, and IL-2RB, is involved in T cell-mediated immune responses. CD122/IL-2RB is present in 3 forms concernin...
TMPY-04031	CD122/IL2RB Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Interleukin-2 receptor (IL-2R) also known as High-affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, and IL-2RB, is involved in T cell-mediated immune responses. CD122/IL-2RB is present in 3 forms concernin...
TMPY-05784	CD122/IL2RB Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Interleukin-2 receptor (IL-2R) also known as High-affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, and IL-2RB, is involved in T cell-mediated immune responses. CD122/IL-2RB is present in 3 forms concernin...
TMPY-03956	Fas Ligand Protein, Human, Recombinant (His)	Human	Yeast
	Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells su...
TMPY-03967	BTN3A3 Protein, Human, Recombinant (His)	Human	HEK293
	The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. The butyrophilin 3 (BTN3) receptors a...
TMPY-00072	GITR/TNFRSF18 Protein, Human, Recombinant (His)	Human	HEK293
	GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)...
TMPY-06076	LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc)	Human	HEK293
	LILRA2 (Leukocyte Immunoglobulin Like Receptor A2, also known as LIR7 and ILT1) is a Protein Coding gene. The encoded protein is an activating receptor that inhibits dendritic cell differentiation and antigen presentatio...
TMPJ-00139	4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His)	Human	E. coli
	Tumor necrosis factor ligand superfamily member 9(4-1BBL) is single-pass type II membrane protein which is a member of the the tumor necrosis factor family. 4-1BBL is a 254 amino acids cytokine that is expressed in brain...
TMPY-04779	BTN3A2 Protein, Human, Recombinant (His)	Human	HEK293
	The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A2 is overexpressed in gastric tu...
TMPY-05842	IL-11 Protein, Cynomolgus, Recombinant	Cynomolgus	E. coli
	IL11 is a multifunctional cytokine first isolated in 199 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 i...
TMPY-00369	LY6D Protein, Human, Recombinant (mFc)	Human	HEK293
	LY6D (Lymphocyte Antigen 6 Family Member D) is a Protein Coding gene. It may act as a specification marker at the earliest stage specification of lymphocytes between B- and T-cell development. Marks the earliest stage of...
TMPY-00817	Granzyme B/GZMB Protein, Human, Recombinant (His)	Human	HEK293
	Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the ...
TMPY-01827	CD30/TNFRSF8 Protein, Human, Recombinant (His)	Human	HEK293
	CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of...
TMPY-04793	IL-35 Protein, Human, Recombinant (Flag & His)	Human	HEK293
	IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, ...
TMPY-04178	IL-11 Protein, Mouse, Recombinant	Mouse	E. coli
	IL11 is a multifunctional cytokine first isolated in 199 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 i...
TMPJ-01469	NGF Protein, Human, Recombinant (E. colli)	Mouse	E.coli
	NGF is the first member discovered in the Neurotrophin family, which includes brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). These proteins belong to the cysteine-knot family ...
TMPY-03488	IL-11 Protein, Human, Recombinant	Human	E. coli
	IL11 is a multifunctional cytokine first isolated in 199 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 i...
TMPY-01851	CD73 Protein, Human, Recombinant (His)	Human	HEK293
	5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf...
TMPY-03377	CD73 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf...
TMPY-00095	IL-3 Protein, Human, Recombinant (His)	Human	HEK293
	IL3 (interleukin 3), also known as IL-3, is a potent growth-promoting cytokine that belongs to the IL-3 family. IL3/IL-3 also belongs to the group of interleukins. Interleukins are produced by a wide variety of body cell...
TMPY-00297	IL-3 Protein, Human, Recombinant(aa 20-152)	Human	E. coli
	IL3 (interleukin 3), also known as IL-3, is a potent growth-promoting cytokine that belongs to the IL-3 family. IL3/IL-3 also belongs to the group of interleukins. Interleukins are produced by a wide variety of body cell...
TMPY-00694	Carbonic Anhydrase 12 Protein, Human, Recombinant (His)	Human	HEK293
	Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respi...
TMPY-00638	Interferon alpha B/IFNA8 Protein, Human, Recombinant (His)	Human	HEK293
	Interferon alpha-B, also known as IFNA8, belongs to the alpha/beta interferon family. Interferons are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites...
TMPY-05016	HHLA2 Protein, Human, Recombinant (His)	Human	HEK293
	B7H7 gene encodes a protein-ligand found on the surface of monocytes. The encoded protein is thought to regulate cell-mediated immunity by binding to a receptor on T lymphocytes and inhibiting the proliferation of these ...
TMPY-04925	CD8 beta Protein, Human, Recombinant, Biotinylated	Human	HEK293
	CD8B (CD8b molecule), also known as P37 and LEU2, contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-...
TMPY-01342	CD73 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf...
TMPY-03540	CD73 Protein, Rat, Recombinant (His)	Rat	HEK293
	5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf...
TMPY-04845	IL-3 Protein, Mouse, Recombinant	Mouse	HEK293
	IL3 (interleukin 3), also known as IL-3, is a potent growth-promoting cytokine that belongs to the IL-3 family. IL3/IL-3 also belongs to the group of interleukins. Interleukins are produced by a wide variety of body cell...
TMPY-01226	CD4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre...
TMPY-05384	CD4 Protein, Human, Recombinant (hFc)	Human	HEK293
	T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre...
TMPY-05319	BCMA/TNFRSF17 Protein, Human, Recombinant (His)	Human	HEK293
	Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-02515	Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc)	Human	HEK293
	Interferon alpha-7(IFNA7) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a c...
TMPY-01371	IL-17RA Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secret...
TMPY-01400	CD4 Protein, Human, Recombinant (His)	Human	HEK293
	T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre...
TMPY-02788	IL-2 Protein, Mouse, Recombinant	Mouse	E. coli
	Interleukin-2, also known as a T-cell growth factor, TCGF, Aldesleukin, and IL2, is a secreted protein that belongs to the IL-2 family. Interleukin-2 / IL-2 was the first interleukin molecule to be discovered. Interleuki...
TMPY-02457	IL-2 Protein, Rat, Recombinant	Rat	E. coli
	Interleukin-2, also known as a T-cell growth factor, TCGF, Aldesleukin, and IL2, is a secreted protein that belongs to the IL-2 family. Interleukin-2 / IL-2 was the first interleukin molecule to be discovered. Interleuki...
TMPY-02031	B7-H3 Protein, Human, Recombinant (His)	Human	HEK293
	B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei...
TMPY-03481	IL-1R2 Protein, Human, Recombinant	Human	HEK293
	Interleukin 1 receptor, type II (IL1R2) also known as CD121b (Cluster of Differentiation 121b) is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein binds interleukin alpha (IL1A), interl...
TMPY-01151	IFNGR1 Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-02153	TNF beta Protein, Human, Recombinant	Human	E. coli
	Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lympho...
TMPY-04064	B7-H3 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei...
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Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His)

TMPY-04578

Species: Human

Expression System: Yeast

CD2 Protein, Human, Recombinant (His)

TMPY-01255

Species: Human

Expression System: HEK293

CD122/IL2RB Protein, Human, Recombinant

TMPY-00860

Species: Human

Expression System: HEK293

CD122/IL2RB Protein, Rat, Recombinant (His)

TMPY-05102

Species: Rat

Expression System: HEK293

CD44 Protein, Mouse, Recombinant (His)

TMPY-05047

Species: Mouse

Expression System: HEK293

CD70 Protein, Human, Recombinant (hFc)

TMPY-01068

Species: Human

Expression System: HEK293

CD122/IL2RB Protein, Rhesus, Recombinant (His)

TMPY-04717

Species: Rhesus

Expression System: HEK293

CD44 Protein, Human, Recombinant (His)

TMPY-02033

Species: Human

Expression System: HEK293

CD122/IL2RB Protein, Human, Recombinant (His)

TMPY-05216

Species: Human

Expression System: Baculovirus-Insect Cells

CD122/IL2RB Protein, Human, Recombinant (mFc)

TMPY-05680

Species: Human

Expression System: HEK293

CD122/IL2RB Protein, Mouse, Recombinant (His)

TMPY-04031

Species: Mouse

Expression System: HEK293

CD122/IL2RB Protein, Mouse, Recombinant (hFc)

TMPY-05784

Species: Mouse

Expression System: HEK293

Fas Ligand Protein, Human, Recombinant (His)

TMPY-03956

Species: Human

Expression System: Yeast

BTN3A3 Protein, Human, Recombinant (His)

TMPY-03967

Species: Human

Expression System: HEK293

GITR/TNFRSF18 Protein, Human, Recombinant (His)

TMPY-00072

Species: Human

Expression System: HEK293

LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc)

TMPY-06076

Species: Human

Expression System: HEK293

4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His)

TMPJ-00139

Species: Human

Expression System: E. coli

BTN3A2 Protein, Human, Recombinant (His)

TMPY-04779

Species: Human

Expression System: HEK293

IL-11 Protein, Cynomolgus, Recombinant

TMPY-05842

Species: Cynomolgus

Expression System: E. coli

LY6D Protein, Human, Recombinant (mFc)

TMPY-00369

Species: Human

Expression System: HEK293

Granzyme B/GZMB Protein, Human, Recombinant (His)

TMPY-00817

Species: Human

Expression System: HEK293

CD30/TNFRSF8 Protein, Human, Recombinant (His)

TMPY-01827

Species: Human

Expression System: HEK293

IL-35 Protein, Human, Recombinant (Flag & His)

TMPY-04793

Species: Human

Expression System: HEK293

IL-11 Protein, Mouse, Recombinant

TMPY-04178

Species: Mouse

Expression System: E. coli

NGF Protein, Human, Recombinant (E. colli)

TMPJ-01469

Species: Mouse

Expression System: E.coli

IL-11 Protein, Human, Recombinant

TMPY-03488

Species: Human

Expression System: E. coli

CD73 Protein, Human, Recombinant (His)

TMPY-01851

Species: Human

Expression System: HEK293

CD73 Protein, Cynomolgus, Recombinant (His)

TMPY-03377

Species: Cynomolgus

Expression System: HEK293

IL-3 Protein, Human, Recombinant (His)

TMPY-00095

Species: Human

Expression System: HEK293

IL-3 Protein, Human, Recombinant(aa 20-152)

TMPY-00297

Species: Human

Expression System: E. coli

Carbonic Anhydrase 12 Protein, Human, Recombinant (His)

TMPY-00694

Species: Human

Expression System: HEK293

Interferon alpha B/IFNA8 Protein, Human, Recombinant (His)

TMPY-00638

Species: Human

Expression System: HEK293

HHLA2 Protein, Human, Recombinant (His)

TMPY-05016

Species: Human

Expression System: HEK293

CD8 beta Protein, Human, Recombinant, Biotinylated

TMPY-04925

Species: Human

Expression System: HEK293

CD73 Protein, Mouse, Recombinant (His)

TMPY-01342

Species: Mouse

Expression System: HEK293

CD73 Protein, Rat, Recombinant (His)

TMPY-03540

Species: Rat

Expression System: HEK293

IL-3 Protein, Mouse, Recombinant

TMPY-04845

Species: Mouse

Expression System: HEK293

CD4 Protein, Mouse, Recombinant (His)

TMPY-01226

Species: Mouse

Expression System: HEK293

CD4 Protein, Human, Recombinant (hFc)

TMPY-05384

Species: Human

Expression System: HEK293

BCMA/TNFRSF17 Protein, Human, Recombinant (His)

TMPY-05319

Species: Human

Expression System: HEK293

Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc)

TMPY-02515

Species: Human

Expression System: HEK293

IL-17RA Protein, Human, Recombinant (His)

TMPY-01371

Species: Human

Expression System: HEK293

CD4 Protein, Human, Recombinant (His)

TMPY-01400

Species: Human

Expression System: HEK293

IL-2 Protein, Mouse, Recombinant

TMPY-02788

Species: Mouse

Expression System: E. coli

IL-2 Protein, Rat, Recombinant

TMPY-02457

Species: Rat

Expression System: E. coli

B7-H3 Protein, Human, Recombinant (His)

TMPY-02031

Species: Human

Expression System: HEK293

IL-1R2 Protein, Human, Recombinant

TMPY-03481

Species: Human

Expression System: HEK293

IFNGR1 Protein, Human, Recombinant (His)

TMPY-01151

Species: Human

Expression System: HEK293

TNF beta Protein, Human, Recombinant

TMPY-02153

Species: Human

Expression System: E. coli

B7-H3 Protein, Mouse, Recombinant (His)

TMPY-04064

Species: Mouse

Expression System: HEK293

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Cat No.	Product Name
L9420	Exosome Compound Library	80 compounds
	80 exosome-related compounds that can be used for high-throughput and high-content screening.
L4100	TGF-beta/Smad Compound Library	185 compounds
	A unique collection of 185 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;

Libraries

Exosome Compound Library

L9420

Compounds: 80

TGF-beta/Smad Compound Library

L4100

Compounds: 185