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JNJ-5207852 is a novel, non-imidazole histamine H3 receptor antagonist, with high affinity at the rat (pKi=8.9) and human (pKi=9.24) H3 receptor.

JNJ-5207852 dihydrochloride is a novel, non-imidazole histamine H3 receptor antagonist, with high affinity at the rat (pKi=8.9) and human (pKi=9.24) H3 receptor.

ZL0580 induces HIV suppression by inhibiting Tat transactivation and transcription elongation as well as by inducing repressive chromatin structure at the HIV promoter.

Metsulfuron-methyl is a systemic selective wheat field high-efficiency sulfonylurea herbicide, which mainly controls most broadleaf weeds and grass weeds in wheat fields.

1. Pseudoprotodioscin has moderate cytotoxicity.

Clevudine (Levovir) is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate. The triphosphate metabolite competes with thymidine for incorporation into viral DNA, thereby causing DNA chain termination and inhibiting the function of HBV DNA polymerase (reverse transcriptase). Clevudine has a long half-life and shows significant reduction of covalently closed circular DNA (cccDNA), therefore the patient is less likely to have a relapse after treatment is discontinued.

DCLK1-IN-1 is a selective, in vivo compatible chemical probe of the kinase domain of doublecortin-like kinase 1 (DCLK1) and a highly selective DCLK1/2 inhibitor with IC50 values ​​of 9.5/57.2 nM (DCLK1) and 31/103 nM (DCLK2) by binding and kinase assays, respectively. It has low toxicity and is used to study DCLK1 biology and determine its role in cancer.

ACH-000143 have been identified as a novel agonist of the melatonin receptors MT1 and MT2.

Oxidized low density lipoprotein (Human) (Human ox-LDL) plays a crucial role in atherogenesis and contributes to endothelial dysfunction through the cytoplasmic adapter protein TRAF3IP2. This compound also promotes endothelial cell activation, leads to increased production of adhesion molecules, and reduces eNOS activity and NO production. Additionally, Human ox-LDL activates the NLRP3 inflammasome in macrophages.

Poly(guluronate), low endotoxin, represents the segment of the Alginate molecule responsible for its gelling properties, featuring ionic cross-linking.

Agarose (Low melting point) is a type of agarose, a polysaccharide derived from seaweed, commonly used in molecular biology and biochemistry for isolating and purifying DNA and RNA fragments. This low melting point agarose is suitable for recovering large DNA fragments and enzymatic reactions in gels, as well as for applications in pulsed field gel electrophoresis and capillary electrophoresis for genetic material analysis.

Ovalbumin (low endotoxin) is the predominant protein found in egg whites and exhibits various biological activities, including anti-cancer, antihypertensive, antibacterial, antioxidant, and immunomodulatory properties. Ovalbumin (low endotoxin) are synthesized as the most abundant protein in oviducts treated with progesterone or estrogen, and they are commonly used as markers in studies of hormone regulation on gene expression in tissues.

Low-density lipoprotein (human) is one of the five main lipoproteins responsible for transporting cholesterol to various tissues such as the adrenal glands, gonads, muscle, and adipose tissue.

Oxidized low density lipoprotein (mouse) is a modified form of low-density lipoprotein (LDL). It induces atherosclerosis (AS) by promoting endothelial dysfunction and accelerating the growth and migration of vascular smooth muscle cells (VSMCs).

Dextran sulfate, low sulfate (MW 5000), is a natural biopolymer and a sulfated polysaccharide. It exhibits antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound healing properties. Additionally, dextran sulfate serves as an additive in cell culture media to prevent cell aggregation and functions as a gel-forming agent in cosmetics.

Dextran sulfate, low sulfate (MW 40000) is a sulfated polysaccharide biopolymer. It exhibits antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound healing properties. Additionally, dextran sulfate can be employed as an additive in cell culture media to prevent cell clumping and as a gelling agent in cosmetic formulations.

Safflower yellow is extracted from the flowers of the plant safflower (Carthamus tinctorius) and as the traditional Chinese medicine it has been extensively used for the treatment of cardio cerebrovascular diseases.

Sunset Yellow FCF (Sunset yellow) is an orange azo dye with pH-dependent absorbance.Sunset Yellow FCF is used in food, cosmetics and pharmaceuticals.It is used as a colorant food additive in many food products.They may be cytotoxic and genotoxic, so care must be taken when using these materials as food additives.

Hydroxysafflor yellow A (Safflomin A) inhibits adipogenesis by increasing HSL promoter activities, effectively protects the liver from long-term alcohol injury by enhancing antioxidant capacity and inhibiting the expression of TGF-β, prevents steroid-induced avascular necrosis of the femoral head by inhibiting primary bone marrow-derived mesenchymal stromal cells, and exhibits anti-tumor effects.

Safflower yellow (Saffron powder) is extracted from the flowers of the plant safflower (Carthamus tinctorius). As traditional Chinese medicine, safflower has been extensively used for the treatment of cardio-cerebrovascular diseases.

Lipid-lowering agent-1 is a potent lipid-lowering compound that significantly inhibits the pharmacological effects of low-density lipoprotein cholesterol (LDLC) and promotes high-density lipoprotein cholesterol (HDLC) production. In rats on a high-fat diet, it substantially reduces fat.

C.I. Pigment Yellow 74 is a bioactive chemical.

Alcian yellow is a biomarker.

C.I. Vat Yellow 4 is a viscous orange liquid. Used for coloring of cotton, wool and cellulose acetate.