l 345

L 345 is a bioactive chemical.

6-Glucosyl-3,4',5,7-tetrahydroxyflavanone is a useful organic compound for research related to life sciences and the catalog number is T130743.

ML-345 is a selective and potent IDE (insulin-degrading enzyme) inhibitor (IC50=188 nM) targeting the cysteine residue Cys819 in IDE, suitable for studying type 2 diabetes and Alzheimer's disease.

Preterramide C is a fungal metabolite that has been found inA. terreus.1It is active againstS. aureus(MIC = 52.4 μM) but notE. aerogenes,P. aeruginosa, orC. albicans(MICs = >100 μM for all).2Preterramide C inhibits the growth of L5178Y mouse lymphoma cells with an IC50value of 0.1 μg/ml.3It also inhibits nitric oxide (NO) production induced by LPS in RAW 264.7 cells (IC50= 5.48 μM).

(3S,4R,5S)-Methyl 3,4,5,6-tetrahydroxy-2-oxohexanoate is a useful organic compound for research related to life sciences. The catalog number is T65295 and the CAS number is 3031-98-9.

Methyl 3,4,5-trimethoxycinnamate may protect the heart from arrhythmias via its inhibitory effect on calcium channel.

Ethyl 3,4,5-trimethoxybenzoate is a natural product derived from Rauvolfia verticillata.

L-Pyrohomoglutamic acid is an amino acid building block.1,2It has been used in the synthesis of ligands for FK506-binding proteins (FKBPs) and histone deacetylase (HDAC) inhibitors. 1.Pomplun, S., Wang, Y., Kirschner, A., et al.Rational design and asymmetric synthesis of potent and neurotrophic ligands for FK506-binding proteins (FKBPs)Angew. Chem. Int. Ed.54(1)345-348(2015) 2.Taddei, M., Cini, E., Giannotti, L., et al.Lactam based 7-amino suberoylamide hydroxamic acids as potent HDAC inhibitorsBioorg. Med. Chem. Lett.24(1)61-64(2014)