15
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15643 | Kainic acid | Others | |
In the CNS, Kainic acid is an effective agonist at excitatory amino acid receptor subtypes. | |||
T37557 | (-)-(α)-Kainic Acid (hydrate) | ||
(-)-(α)-Kainic Acid (hydrate) is a potent excitotoxic agent that can induce seizures. (-)-(α)-Kainic Acid (hydrate) is also an agonist of ionotropic glutamate receptor subtypes. | |||
T23012 | MNI caged kainic acid | Others | |
Generates large inward currents at resting membrane potential | |||
TN7044 | S-(4-Hydroxybenzyl)glutathione | GluR | |
L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia ela... | |||
T16800 | (RS)-AMPA | (±)-AMPA | iGluR |
(RS)-AMPA ((±)-AMPA) is a glutamate analog. (RS)-AMPA is an agonist of effective and selective excitatory neurotransmitter L-glutamic acid. | |||
T22722 | Dihydrokainic acid | Others | |
EAAT2(GLT1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake | |||
T3S1416 | Decursin | Decursinol angelate,(+)-Decursin | Apoptosis , PKC |
1. Decursin (Decursinol angelate) is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug. 2. Decursin exhibits hepatoprotective effects , potentially by inhibiting the TGF-β1 ... | |||
T25853 | NBQX Disodium | FG9202 disodium,NBQX 2Na | GluR |
NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity. NBQX Disodium is a salt of NBQX. NBQX is a potent and selective AMPA/rhodosina... | |||
T20223 | Domoic acid | NSC 288031,NSC-288031,NSC288031,L-Domoic acid | |
Domoic acid is a kainic acid analog. | |||
T71030 | 3-ATA | ||
3-ATA is a selective cyclin-dependent kinase 4 (Cdk4) inhibitor, attenuating kainic acid-induced apoptosis in neurons. | |||
T69017 | Ibotenic acid hydrate | ||
Ibotenic acid hydrate is a neurotoxic isoxazole (similar to Kainic acid and Muscimol) found in Amanita mushrooms. It causes motor depression, ataxia, and changes in mood, perceptions and feelings, and is a potent excitat... | |||
T36178 | Aspalatone | ||
Aspalatone is an anti-platelet aggregator (IC50 = 180 μM, in vitro) that prolongs bleeding time significantly in a rodent model of thromboembolism. Additionally at a minimal effective dose of 24 mg/kg, aspalatone generat... | |||
T60750 | Neuronotoxicity-IN-1 | ||
Neuronotoxicity-IN-1 is a pyridothiazine derivative. Neuronotoxicity-IN-1 is an inhibitor of kainic acid neurotoxicity with neuroprotective activity[1]. | |||
T60242 | (RS)-AMPA monohydrate | ||
(RS)-AMPA ((±)-AMPA) monohydrate, a potent and selective agonist of the excitatory neurotransmitter L-glutamic acid, is a glutamate analogue. It specifically does not interact with the binding sites of kainic acid or NMD... | |||
T81674 | NIR-FP | ||
NIR-FP is a near-infrared (NIR) fluorescent probe that exhibits high sensitivity and selectivity toward the superoxide anion (O2-), a principal precursor of reactive oxygen species (ROS). This probe facilitates dynamic m... |