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Search Results for " kainic "

15

Compounds

Cat No. Product Name Synonyms Targets
T15643 Kainic acid Others
In the CNS, Kainic acid is an effective agonist at excitatory amino acid receptor subtypes.
T37557 (-)-(α)-Kainic Acid (hydrate)
(-)-(α)-Kainic Acid (hydrate) is a potent excitotoxic agent that can induce seizures. (-)-(α)-Kainic Acid (hydrate) is also an agonist of ionotropic glutamate receptor subtypes.
T23012 MNI caged kainic acid Others
Generates large inward currents at resting membrane potential
TN7044 S-(4-Hydroxybenzyl)glutathione GluR
L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia ela...
T16800 (RS)-AMPA (±)-AMPA iGluR
(RS)-AMPA ((±)-AMPA) is a glutamate analog. (RS)-AMPA is an agonist of effective and selective excitatory neurotransmitter L-glutamic acid.
T22722 Dihydrokainic acid Others
EAAT2(GLT1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake
T3S1416 Decursin Decursinol angelate,(+)-Decursin Apoptosis , PKC
1. Decursin (Decursinol angelate) is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug. 2. Decursin exhibits hepatoprotective effects , potentially by inhibiting the TGF-β1 ...
T25853 NBQX Disodium FG9202 disodium,NBQX 2Na GluR
NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity. NBQX Disodium is a salt of NBQX. NBQX is a potent and selective AMPA/rhodosina...
T20223 Domoic acid NSC 288031,NSC-288031,NSC288031,L-Domoic acid
Domoic acid is a kainic acid analog.
T71030 3-ATA
3-ATA is a selective cyclin-dependent kinase 4 (Cdk4) inhibitor, attenuating kainic acid-induced apoptosis in neurons.
T69017 Ibotenic acid hydrate
Ibotenic acid hydrate is a neurotoxic isoxazole (similar to Kainic acid and Muscimol) found in Amanita mushrooms. It causes motor depression, ataxia, and changes in mood, perceptions and feelings, and is a potent excitat...
T36178 Aspalatone
Aspalatone is an anti-platelet aggregator (IC50 = 180 μM, in vitro) that prolongs bleeding time significantly in a rodent model of thromboembolism. Additionally at a minimal effective dose of 24 mg/kg, aspalatone generat...
T60750 Neuronotoxicity-IN-1
Neuronotoxicity-IN-1 is a pyridothiazine derivative. Neuronotoxicity-IN-1 is an inhibitor of kainic acid neurotoxicity with neuroprotective activity[1].
T60242 (RS)-AMPA monohydrate
(RS)-AMPA ((±)-AMPA) monohydrate, a potent and selective agonist of the excitatory neurotransmitter L-glutamic acid, is a glutamate analogue. It specifically does not interact with the binding sites of kainic acid or NMD...
T81674 NIR-FP
NIR-FP is a near-infrared (NIR) fluorescent probe that exhibits high sensitivity and selectivity toward the superoxide anion (O2-), a principal precursor of reactive oxygen species (ROS). This probe facilitates dynamic m...
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