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il-17 production

" in TargetMol Product Catalog
  • Inhibitors & Agonists
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Brodalumab
LP 0160, KHK-4827, AMG-827
T767791174395-19-7
Brodalumab (AMG 827) is a human monoclonal IgG2 antibody targeting the interleukin 17 receptor (IL-17R), commonly used as an immunosuppressant in treating psoriasis.
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Risankizumab
SKYRIZI, Risankizumab rzaa, BI-655066, ABBV 066
T767781612838-76-2
Risankizumab (BI 655066) is a humanized IgG monoclonal antibody (Kd <10 pM) targeting the IL-23 p19 subunit. It inhibits IL-17 production induced by human IL-23 in mouse splenocytes with an IC50 value of 2 pM. Risankizumab is used for the prevention and treatment of immune and inflammatory disorders such as psoriasis vulgaris, psoriatic arthritis, generalized pustular psoriasis, and erythrodermic psoriasis.
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