hydroxamic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T21505	Suberoyl bis-hydroxamic acid	SBHA,Suberohydroxamic acid	Apoptosis , HDAC
	Suberoyl bis-hydroxamic acid (SBHA) is a Histone deacetylase (HDAC) inhibitor. HDAC is required for transcriptional modulation, cell cycle regulation and development. It is an enzyme that deacetylates lysine residues on ...		Apoptosis , HDAC
T1583	Vorinostat	MK0683,suberoylanilide hydroxamic acid,SAHA	Apoptosis , Mitophagy , Virus Protease , HDAC , Autophagy
	Vorinostat (SAHA) is a pan-histone deacetylase (HDAC) inhibitor (IC50=10 nM) with inhibitory activity against HDAC1/2/3/6/7/11. Vorinostat has antitumor activity, induces cell differentiation, blocks the cell cycle and i...		Apoptosis , Mitophagy , Virus Protease , HDAC , Autophagy
T36105	Coumarin-SAHA	coumarin-Suberoylanilide Hydroxamic Acid,coumarin-SAHA
	Suberoylanilide hydroxamic acid (SAHA) is a class I and class II histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. [1] coumarin-Suberoylanili...
T14864	Caracemide	NSC-253272	Others , DNA/RNA Synthesis , Antibacterial
	Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.		Others , DNA/RNA Synthesis , Antibacterial
T13996	1-Naphthohydroxamic acid		HDAC
	1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 μM, and it is more selectively for HDAC8 than class I HDAC1 and class II HDAC6 (IC50 >100 μM). 1-Naphthohydroxamic acid d...		HDAC
T1592	Acetohydroxamic acid	Methylhydroxamic acid,Acetic acid,Lithostat,AHA,oxime,N-Hydroxyacetamide	MMP , Antibacterial
	Acetohydroxamic acid (N-Hydroxyacetamide) is an antagonist of the bacterial enzyme urease.		MMP , Antibacterial
T72148	Phosphoglycolohydroxamic acid
	Phosphoglycolohydroxamic acid, acting as a potent inhibitor of both aldolase and triose-phosphate isomerase, serves a crucial role in the research of antibacterial and antifungal domains.
T33614	N-Decanohydroxamic acid	N-Hydroxydecanamide,Decanohydroxamic acid,Caprinohydroxamic acid
	n-Decanohydroxamic acid is a biochemical.
T14043	4-(tert-Butyl)-benzhydroxamic Acid		Others
	4-(tert-Butyl)-benzhydroxamic Acid is a PqsR antagonist with IC50s of 12.5 μM and 23.6 μM for E. coli and P. aeruginosa, respectively, and it reduces the production of the virulence factor pyocyanin in P. aeruginosa with...		Others
TQ0052	SH5-07		STAT
	SH5-07 is a hydroxamic acid-based Stat3 inhibitor (IC50: 3.9 μM).		STAT
T0721	Piroctone olamine	Piroctone ethanolamine	Antibiotic , Antifungal
	Piroctone olamine (Piroctone ethanolamine) is a compound sometimes used in the treatment of fungal infections. Piroctone olamine is the ethanolamine salt of the hydroxamic acid derivative piroctone.		Antibiotic , Antifungal
T8517	Belinostat	PX105684,PXD101,PXD-101	HDAC , Autophagy
	Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.		HDAC , Autophagy
T16729	Remetinostat	SHP-141	HDAC
	Remetinostat (SHP-141), a hydroxamic acid-based inhibitor of histone deacetylase enzymes, is currently being developed for the treatment of cutaneous T-cell lymphoma.		HDAC
T1852	Rac-Belinostat	NSC726630,PXD101,PX-105684	HDAC
	Rac-Belinostat (PX-105684) is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptos...		HDAC
T33551	N(alpha)-Acetylfusarinines	Nalpha-Acetylfusarinines
	N(alpha)-Acetylfusarinines is a group of naturally occurring hydroxamic acids produced by unidentified species of Penicillium when grown on iron-deficient media.
T68085	Idrapril
	Idrapril,an angiotensin-converting enzyme (ACE) inhibitor acts by binding the catalytically important zinc ion to a hydroxamic group.
T74166	Microtubule destabilizing agent-1
	Microtubule destabilizing agent-1 (Compound 12b), a hydroxamic acid-based microtubule destabilizing agent (MDA), exhibits potent antitumor activity, favorable metabolic stability, and high bioavailability, making it a pr...
T35765	SAHA-BPyne
	Suberoylanilide hydroxamic acid (SAHA) is a class I and class II histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. SAHA-BPyne is a SAHA deriva...
T71110	Nanatinostat TFA
	Nanatinostat, also known as Tractinostat, CHR-3996 and VRx-3996, is an orally bioavailable, second-generation hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potential antineoplastic activity. HDAC inh...
T36110	L-Pyrohomoglutamic Acid
	L-Pyrohomoglutamic acid is an amino acid building block.1,2It has been used in the synthesis of ligands for FK506-binding proteins (FKBPs) and histone deacetylase (HDAC) inhibitors. 1.Pomplun, S., Wang, Y., Kirschner, A....