hepato-protective

Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.

Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.

SY-640 is an Acetamide derivative. SY-640 exhibits potent hepatoprotective effect. SY-640 reduces liver injury in mice induced by Propionibacterium acnes and Lipopolysaccharide.

4'-Hydroxychalcone (2-Benzal-4-Hydroxyacetophenone) is a chalcone metabolite with hepatoprotective activity

Schisandrin (Wuweizi alcohol-A) is a compound with anti-asthmatic, anti-cancer, and anti-inflammatory effects.

Aucubin (Rhinanthin) is an iridoid glycoside with anti-inflammatory, anti-microbial, anti-algesic as well as anti-tumor activities.

3,4-Dicaffeoylquinic acid (Isochlorogenic acid B) has antioxidant activity.

Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly suppresses melanin biosynthesis in murine B16 melanoma cells. It is active in the inhibition of a

Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM.

Phyllanthin is widely used as hepatoprotective and antigenotoxic and inhibit function of P-gp.

7-Methylcoumarin with strong hepatoprotective activity.

Compound 11, labeled as a weak Hepatoprotective agent-1, is a naturally occurring substance extracted from the fruits of Arctium lappa L. It demonstrates modest hepatoprotective effects when applied at a concentration of 10 μM [1].

1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has anti-inflammatory property, potentially result from the inhibition of COX-2, iNOS, IL-6, TNF-α and NO through the down-regulation of RIP2 and NF-κB activation. 3. Schisandrol B induces marked protective effects against hepatic and renal injury induced by CCl(4) exposure through differential regulation of the MAPK signal transduction pathway. 4. Schisandrol B significantly inhibits cell proliferation in a dose-dependent manner, due to cell cycle arrest in the G1 phase with the downregulation of cyclin D1 expression and Retinoblastoma (RB) phosphorylation.

Hepatoprotective agent-1 (compound 1b) functions as a hepatoprotective agent, exhibiting anti-inflammatory, antiapoptotic, and antifibrotic effects [1].

Hepatoprotective agent-2 (compound 2a), a 4-phenyl-tetrahydroquinoline derivative, not only demonstrates significant hepatoprotective effects but also possesses antiapoptotic activity. It effectively mitigates chemically induced increases in hepatic indicators, which are symptomatic of liver damage [1].

Secoxyloganin possesses a hepato-protective effect. Secoxyloganin possesses antibacterial activity. Secoxyloganin has cytotoxic activity against UACC-62 cell line.Secoxyloganin possesses the perfect protective effect on PRRSV infected cell and with the minimum protection concentration of 6. 25 μg/mL.

1. Alisol B 23-acetate (Alisol B Acetate) produces protective effect against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes. 2. Alisol B 23-acetate produces promotive effect on liver regeneration, due to FXR-mediated regulation of genes involved in hepatocyte proliferation and hepato-protection. 3. Alisol B 23-acetate produces a protective effect against CCl4-induced hepatotoxicity, due to FXR and STAT3-mediated gene regulation.

Alisol B 23-acetate (Standard) is a reference standard for research and analysis in studies involving Alisol B 23-acetate. 1. Alisol B 23-acetate (Alisol B Acetate) produces protective effect against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes. 2. Alisol B 23-acetate produces promotive effect on liver regeneration, due to FXR-mediated regulation of genes involved in hepatocyte proliferation and hepato-protection. 3. Alisol B 23-acetate produces a protective effect against CCl4-induced hepatotoxicity, due to FXR and STAT3-mediated gene regulation.

Secoxyloganin (Standard) is a reference standard for research and analysis in studies involving Secoxyloganin. Secoxyloganin possesses a hepato-protective effect. Secoxyloganin possesses antibacterial activity. Secoxyloganin has cytotoxic activity against UACC-62 cell line.Secoxyloganin possesses the perfect protective effect on PRRSV infected cell and with the minimum protection concentration of 6. 25 μg/mL.

"(±)-ε-Viniferin, a racemate of ε-Viniferin, exhibits P450 inhibitory antioxidants, along with hepato-protective and antimicrobial activities. It also demonstrates antibacterial and antibiofilm activities against Gram-positive bacteria Streptococcus pneumoniae, with a minimum inhibitory concentration (MIC) of 20 μM [1]."