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Results for "

fusion

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    231
    TargetMol | Inhibitors_Agonists
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    36
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    TargetMol | Inhibitors_Agonists
NNMTi
5-Amino-1-methylquinolinium
T876042464-96-0
NNMTi (5-Amino-1-methylquinolinium) is a substrate site-targeting, selective nicotinamide N-methyltransferase (NNMT) inhibitor (IC50 = 1.2 μM; 50 μM SAM, 100 μM NCA) that reduces 3T3-L1 lipogenesis (EC50 = 30μM) and adipocytes 1-methylnicotinamide level (EC50 = 2.3 μM) without affecting related methyltransferases & enzymes in the NAD+ salvage pathway
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TAT-HA2 Fusion Peptide
T76546923954-79-4
TAT-HA2 Fusion Peptide, a peptide-based delivery agent, synergizes the pH-sensitive HA2 fusion peptide from Influenza with the cell-penetrating peptide TAT from HIV. This compound facilitates the cellular uptake of macromolecules through the TAT component and triggers their release into cells by exploiting the acidifying endosomal lumen to induce membrane leakage via the HA2 component [1].
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TAT-GluR23A Fusion Peptide
T80246
TAT-GluR23A Fusion Peptide is a bioactive peptide comprising the GluR23A sequence—residues 869 to 877 of GluR23Y with alanine replacing tyrosine—and an 11 amino acid cell-permeable HIV Trans-Activator of Transcription (TAT) protein transduction domain (PTD). It serves as an inactive control counterpart to the glutamate receptor endocytosis inhibitor GluR23Y, devoid of crucial phosphorylation sites.
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TAT-NSF700 Fusion Peptide
T81034
TAT-NSF700 Fusion Peptide, a potent inhibitor of N-ethyl-maleimide-sensitive factor (NSF), possesses the ability to penetrate cell membranes and directly interact with intracellular organelles [1].
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TAT-NSF700 Fusion Peptide acetate
T81034L
TAT-NSF700 Fusion Peptide acetate is a membrane-permeable inhibitor of N-ethyl-maleimide-sensitive factor (NSF), a fusion peptide with potential anti-inflammatory activity.TAT-NSF700 Fusion Peptide acetate interacts with intracellular organelles and can be used to investigate Myocardial ischemia and reperfusion injury.
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TAT-NSF222 Fusion Peptide
T81035
TAT-NSF222 Fusion Peptide is a bifunctional polypeptide comprising a TAT domain for cellular uptake via macropinocytosis and an NSF domain that inhibits N-ethylmaleimide-sensitive factor (NSF), serving as an exocytosis inhibitor [1].
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Fusion Inhibitory Peptide
Z-D-Phe-Phe-Gly-OH, Virus Replication Inhibitory Peptide
T8648075539-79-6
Fusion Inhibitory Peptide (Z-D-Phe-Phe-Gly-OH, FIP, Virus Replication Inhibitory Peptide) effectively blocks virus replication by inhibiting the membrane fusion activity of a specific viral glycoprotein [1].
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10-14 weeks
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Mitochondrial fusion promoter M1
T9232219315-22-7
Mitochondrial fusion promoter M1, a modulator of mitochondrial dynamics, enhances mitochondrial function and cellular respiration, and has shown efficacy in reducing brain and cardiac damage in rats suffering from cardiac ischemia reperfusion injury.
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Anti-Human respiratory syncytial virus (RSV) Fusion Glycoprotein/RSV-F Antibody (1B191)
T9901A-698
Anti-Human respiratory syncytial virus (RSV) Fusion Glycoprotein RSV-F Antibody (1B191) is a Rabbit IgG monoclonal antibody targeting RSV Human respiratory syncytial virus (RSV) Fusion Glycoprotein RSV-F.
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7-10 days
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Fusion glycoprotein (92-106) [Human respiratory syncytial virus]
TP2230
Fusion glycoprotein (92-106) [Human respiratory syncytial virus] is a peptide with the sequence H2N-Glu-Leu-Gln-Leu-Leu-Met-Gln-Ser-Thr-Pro-Pro-Thr-Asn-Asn-Arg-OH, MW= 1741.96.
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FN-A208 fusion peptide
T82379809281-07-0
FN-A208 is an active peptide combining A208 from murine laminin a1 with the fibronectin active site GRGDS, linked by a glycine spacer. This compound self-assembles into amyloid-like fibrils and facilitates fibroblast cell adhesion through actin stress fiber formation, suggesting its use as a bioadhesive in tissue regeneration and engineering. FN-A208 targets IKVAV receptors and integrins, but its function can be inhibited by EDTA.
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Brain Heart Infusion Agar
TXB-00412
Brain Heart Infusion Agar is a medium used for cultivating a variety of microorganisms.
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Brain Heart Infusion Broth
TXB-00537
Brain Heart Infusion Broth (BHI) is used for the cultivation of microorganisms, including Streptococcus, Pneumococcus, and Meningococcus.
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Beef Heart Infusion
TXB-00538
Beef Heart Infusion is a non-selective microbial culture medium that supplies essential nutrients for microorganism growth. It is suitable for the cultivation, subculturing, and revitalization of microorganisms.
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ziresovir
RO-0529, AK0529
T134011422500-60-4In house
Ziresovir (RO-0529) is a respiratory syncytial virus fusion protein (RSV F) inhibitor that inhibits RSV activity and can be used in the study of syncytial virus sensing.
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8-10 weeks
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TargetMol | Inhibitor Hot
MHY1485
T1908326914-06-1
MHY1485 is an mTOR activator that is cell-permeable. MHY1485 inhibits autophagosome and lysosome fusion, leading to accumulation of LC3II proteins and increased autophagosomes, thereby inhibiting cellular autophagy.
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Leupeptin Hemisulfate
T6564103476-89-7
Leupeptin hemisulfate is a protease inhibitor with cell membrane-permeable, reversible, competitive, and oral activities. Leupeptin hemisulfate inhibits the activity of Cathepsin B, Cathepsin H, and Cathepsin L, and blocks fusion of amphipathic lysosomes. Leupeptin hemisulfate also has anti-inflammatory activity.
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TargetMol | Inhibitor Hot
Bafilomycin A1
Baf A1
T674088899-55-2
Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase inhibitor (IC50=0.44 nM) that is specific and reversible. Bafilomycin A1 is an inhibitor of the late phase of autophagy, blocking the fusion of autophagosomes with lysosomes. Bafilomycin A1 also induces apoptosis.
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Olamkicept
TJ-301, TJ301, FE-999301, FE999301, FE-301, FE301
T732091702282-14-1
Olamkicept (FE-301) is a soluble gp130-Fc-fusion protein that selectively inhibits interleukin 6 (IL-6) trans-signaling by binding to the soluble IL-6 receptor IL-6 complex.
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TargetMol | Inhibitor Hot
740 Y-P acetate
PDGFR 740Y-P Acetate, 740YPDGFR acetate, 740 Y-P acetate(1236188-16-1 Free base)
TQ0003L1
740 Y-P acetate (740YPDGFR acetate) is a potent and cell-permeable PI3K activator.740 Y-P acetate tends to bind to GST fusion proteins containing the N- and C-terminal SH2 structural domains of p85, but not to GST alone.
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EACC
T11142864941-31-1In house
EACC, a reversible autophagy inhibitor, selectively impedes Stx17, an autophagosome-specific SNARE, from translocating, hence obstructing the fusion between autophagosomes and lysosomes. This compound effectively halts autophagic flux.
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6-8 weeks
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BTA-9881
MEDI-564, BTA9881, BTA 9881, AZD-9639, AZD9639
T269141646857-24-0In house
BTA-9881 is a novel RSV fusion inhibitor with oral activity and antiviral activity for the study of respiratory syncytial virus infections.
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6-8 weeks
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(R)-AZD 9639
T26914L1646857-28-4In house
(R)-AZD 9639 is the R-isomer of AZD 9639, a novel respiratory syncytial virus (RSV) fusion inhibitor with antiviral activity.
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Enzaplatovir
BTAC585, BTA 585, BTA585, BTA-C585, BTA-585
T272711323077-89-9In house
Enzaplatovir (BTA-585) is an orally available fusion inhibitor with antiviral activity for the study of respiratory syncytial virus infections and coronavirus disease (COVID-19) infections.
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6-8 weeks
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