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By Target- Wnt/beta-catenin
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Results for "
fj 9
" in TargetMol Product Catalog.- Inhibitors & Agonists1
- Antibody Products4
T68468873841-43-1
FJ9 is an effective Wnt/β-catenin antagonist (Ki = 29 μM) that downregulates canonical Wnt signaling, inhibits HSC (hepatic stellate cell) activation, and reduces MeCP2 protein levels. FJ9 also disrupts the protein-protein interaction between Frz7 and the DVL PDZ domain, induces apoptosis in human cancer cell lines, and inhibits tumor growth in a mouse xenograft model.
- $293
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