dtt

DTT (DL-Dithiothreitol) is a strong reducing agent. DTT has anti-disulfide ptosis activity and, upon oxidation, forms a stable six-membered ring with internal disulfide bonds.

L-Dithiothreitol (L-Dtt) is a chiral bidentate dithiol with two stereogenic centers. It may be used in chiroptical response research.

DTT (Standard) is a reference standard for research and analysis in studies involving DTT. DTT (DL-Dithiothreitol) is a strong reducing agent. DTT has anti-disulfide ptosis activity and, upon oxidation, forms a stable six-membered ring with internal disulfide bonds.

ddTTPαS tetrasodium is a sulfur-containing nucleotide triphosphate derivative used in chain extension during PCR assays.

ddTTP, a 2',3'-dideoxyribonucleoside 5'-triphosphate (ddNTP), serves as a chain-elongation inhibitor of DNA polymerase in DNA sequencing [1].

Dideoxythymidine triphosphate trisodium (ddTTP), a 2',3'-dideoxyribonucleoside 5'-triphosphate (ddNTP), functions as a chain-elongation inhibitor of DNA polymerase in DNA sequencing applications [1].

3'-ONH2-dTTP sodium solution (100mM) is a labeled and modified deoxyribonucleotide (dNTP) capable of releasing pyrophosphate to generate fluorescence, making it uniquely applicable in gene synthesis and sequencing.

3′-O-Azidomethyl-dTTP sodium is a labeled and modified deoxyoligonucleotide (dNTP) that can release pyrophosphate and generate fluorescence during gene synthesis and sequencing, so it has special application value.

3'-P-dTTP sodium is a labeled and modified deoxyoligonucleotide (dNTP) that can release pyrophosphate and generate fluorescence during gene synthesis and sequencing, so it has special application value.

3'-NH2-ddTTP sodium is a labeled and modified deoxyoligonucleotide (dNTP) that can release pyrophosphate and generate fluorescence during gene synthesis and sequencing, so it has special application value.

dTTPαS sodium is a labeled and modified deoxyoligonucleotide (dNTP) that can release pyrophosphate and generate fluorescence during gene synthesis and sequencing, so it has special application value.

3'-O-Methylthiomethyl-dTTP sodium is a labeled and modified deoxyoligonucleotide (dNTP) that can release pyrophosphate and generate fluorescence during gene synthesis and sequencing, so it has special application value.

3'-O-Ac-dTTP sodium is an acetylated derivative of nucleoside 5'-triphosphate.

Emivirine (MKC-442) is a potent and selective nonnucleoside reverse transcriptase inhibitor for human immunodeficiency virus type 1.

Deoxythymidine-5'-triphosphate (dTTP) is a nucleoside triphosphate essential for DNA synthesis.

NC-III-49-1 is a potent bivalent bromodomain and extraterminal domain (BET) inhibitor with significant affinity for various BRD4 and BRDT isoforms, as demonstrated by its Kd values of 0.095 nM for BRD4-1, 0.32 nM for BRD4-2, 0.29 nM for BRD4-T, 0.089 nM for BRDT-1, 5.5 nM for BRDT-2, and 0.058 nM for BRDT-T. Additionally, NC-III-49-1 exhibits antiproliferative effects and reduces the expression of c-Myc [1].

GXH-II-052 is a potent bivalent inhibitor targeting the bromodomain and extraterminal domain (BET), exhibiting significant binding affinity to various BET proteins, including BRD4-1, BRD4-2, BRD4-T, BRDT-1, BRDT-2, and BRDT-T, with dissociation constants (Kd) of 28, 9.1, 4.8, 0.6, 8.4, and 2.6 nM, respectively. Additionally, GXH-II-052 demonstrates antiproliferative effects and reduces the expression of c-Myc [1].

Rp-Thymidine-5'-O-(1-thiotriphosphate) (Rp-TTP-α-S), an isomer of the sulfur-containing nucleotide derivative TTP-α-S, selectively interacts with HIV-1 reverse transcriptase, exhibiting dissociation constants (Kds) of 45.7, 27.32, and 39.44 µM in the presence of magnesium, manganate, and cobalt, respectively.

DHATS(Leu-13C6,15N)PVTIPSAVST(Gly-13C6,15N)HTTPLPVTDT (TFA) is an isotopically labeled version of DHATS-PVTIPSAVST-HTTPLPVTDT (TFA), featuring 13C and 15N labels.

Deoxythymidine-5'-triphosphate trisodium (Deoxythymidine-5'-triphosphate (dTTP) trisodium salt) is one of the four natural deoxynucleotides. It is used for the biosynthesis of deoxyribonucleic acid by DNA polymerase and reverse transcriptase.

Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine.

DBCO-S-S-PEG3-biotin is a cleavable reagent for the introduction of a biotin moiety to azide-containing biomolecules using copper-free Click Chemistry. The disulfide bond in this linker can be cleaved with reducing agents such as DTT, BME, and TCEP to remove the biotin label. PEG linkers can also be used in the synthesis of PROTACs.

DTE (Dithioerythritol) is a sulfur-containing sugar derivative of the four-carbon monosaccharide erythrose and is an epimer of dithiothreitol (DTT), Dithioerythritol (DTE) is commonly used as a reducing agent in biochemical and molecular biology experiments to maintain thiol groups in a reduced state, stabilize protein structure, and support redox-sensitive enzymatic and structural studies.

Deac-SS-Biotin, a potent antitumor compound, enters cells via biotin-mediated internalization and, when combined with DTT (Glutathione mimetic), effectively inhibits microtubule assembly, exhibiting enhanced antitumor activity [1].