diosgenin

Diosgenin (Nitogenin) is a spirostan found in DIOSCOREA and other plants. It has favorable effects in the improvement of diabetes and regulation of lipid metabolism.

Diosgenin glucoside (Trillin) and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosis. Significant inhibition of Diosgenin glucoside synthesis and stimulation of solasodine glucosylation was found only with PC molecular species containing fatty acids with a chain length of 12-18 carbon atoms.

Diosgenin-3-O-rhamnosyl(1→2)[glucosyl(1→6)]glucoside (compound 9), a steroidal saponin, is isolated from Paris polyphylla var. yunnanensis, commonly known as Yunnan pine [1].

Diosgenin palmitate (Compound 7) is a steroidal compound found in Dioscorea collettii.

Diosgenin-3-O-β-D-xylosyl-(1→3)-β-glucoside is a natural product that can be used in related research in the field of life sciences. Its product number is TN8740.

Yamogenin is a diastereomer of diosgenin, which we have identified as the compound responsible for the anti-hyperlipidemic effect of fenugreek.