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(1)
By Target- DNA/RNA Synthesis
- IL Receptor(1)
- Tyrosine Kinases(1)
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Results for "
di-03
" in TargetMol Product Catalog- Inhibitors & Agonists2
d-i03
DI03
T10936688342-78-1In house
D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 µM. It specifically inhibits RAD52-dependent single-chain annealing (SSA) and D-loop formation, with IC50 values of 5 µM and 8 µM, respectively. D-I03 also inhibits the growth of BRCA1 and BRCA2 deficient cells and prevents the formation of damage-induced RAD52 foci, but does not affect RAD51 foci induced by Cisplatin.
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NDI-034858
TAK-279
T629022272904-53-5
NDI-034858 (TAK-279) is a tyrosine kinase 2 (TYK2) inhibitor (Kd<200 pM) that targets the JH2 structural domain of Tyk2 for the treatment of autoimmune diseases caused by aberrant expression of IL12 and IL23.
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