deoxycytidine

2',5-Difluoro-2'-deoxycytidine has potent anti-HCV activity and toxicity to rRNA.

5-O-TBDMS-N4-Benzoyl-2-deoxycytidine is a modified nucleoside used in the synthesis of deoxyribonucleic acid (DNA) or nucleic acid.

5'-Ethynyl-2'-deoxycytidine (EdC) functions as a nucleoside analog effectively inhibiting the replication of herpes simplex virus-1 (HSV-1) KOS strain with an ID50 of 0.2 μg/mL. Additionally, it decreases virus-induced cytopathogenic effects in PRK cells for HSV-1, HSV-2, and vaccinia virus strains, demonstrating MIC values between 0.2 to 5 μg/mL. EdC acts as a thymidylate synthetase inhibitor, selectively impacting the DNA incorporation rates of [1',2'-3H]deoxyuridine compared to [CH3-3H]deoxythymidine in PRK cells with ID50s of 3 and 120 μg/mL, respectively. It further inhibits thymidine synthetase and curtails L1210 cell proliferation, a process reversible by deoxythymidine (ID50s are 4.4 and 1,000 μg/mL, respectively). Also, EdC is utilized in monitoring DNA synthesis and cellular replication through click chemistry conjugation, linking its ethynyl group with the azido group of various fluorochromes.

2'-Deoxycytidine (Deoxycytidine) hydrate is a component of nucleic acids.

2'-Deoxycytidine is one of the major nucleosides of DNA consisting of cytosine and deoxyribose and inhibits the biological effects of bromodeoxyuridine (Brdu). The nucleoside consists only of a pentose sugar attached to a purine or pyrimidine base and has no phosphate group. When N1 is attached to C1 of deoxyribose, deoxyribosides and nucleotides are formed from cytosine and deoxyribose; deoxycytidine monophosphate (dCMP), deoxycytidine diphosphate (dCDP), and deoxycytidine triphosphate (dCTP). cTP is the source of cytosine in RNA (ribonucleic acid) and deoxycytidine triphosphate (dCTP) is the source of deoxycytidine in DNA (deoxyribonucleic acid). Itaconic acid is a polymer.

Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) contributes to antibiotic lethality in stationary-phase mycobacteria.

2'-Deoxycytidine hydrochloride is the hydrochloride form of 2'-Deoxycytidine, an important deoxyribonucleoside analog commonly used in DNA synthesis and potentially anticancer, and its derivative Gemcitabine has been developed as an anticancer drug.2'-Deoxycytidine 2'-Deoxycytidine hydrochloride protects mice from the lethal toxicity of cytosine arabinoside(araC).

2'-Deoxycytidine-5'-monophosphoric acid (2'-Deoxycytidine 5'-monophosphate) is a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) that forms dCDP, which, upon phosphorylation to dCTP, supports DNA biosynthesis.

5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.

2'-Deoxycytidine-5'-diphosphate trisodium (dCDP) is used as a substrate of CDP (nucleoside diphosphate) kinase (2.7.4.6) for the production of dCTP to support DNA biosynthesis and reverse transcription.

N4-Benzoyl-2′-deoxycytidine is a synthetic nucleoside analog of the natural nucleoside deoxycytidine (dC), a competitive inhibitor of DNA polymerase. In vitro studies have shown that it inhibits replication in viruses, bacteria and eukaryotic cells. It has also been shown to inhibit tumor cell growth in animal models.

2'-Deoxycytidine (Standard) is the standard substance of 2'-Deoxycytidine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 2'-Deoxycytidine is one of the major nucleosides of DNA consisting of cytosine and deoxyribose and inhibits the biological effects of bromodeoxyuridine (Brdu). The nucleoside consists only of a pentose sugar attached to a purine or pyrimidine base and has no phosphate group. When N1 is attached to C1 of deoxyribose, deoxyribosides and nucleotides are formed from cytosine and deoxyribose; deoxycytidine monophosphate (dCMP), deoxycytidine diphosphate (dCDP), and deoxycytidine triphosphate (dCTP). cTP is the source of cytosine in RNA (ribonucleic acid) and deoxycytidine triphosphate (dCTP) is the source of deoxycytidine in DNA (deoxyribonucleic acid). Itaconic acid is a polymer.

Deoxycytidine triphosphate disodium is a biochemically defined nucleotide reagent that can be utilized as a biological material or organic compound in life science research. Deoxycytidine triphosphate supports applications in DNA synthesis, enzymatic assays, molecular biology workflows, and experimental systems requiring high-purity deoxynucleotide triphosphates for controlled biochemical reactions.

Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity. Decitabine has antitumor activity and antimetabolic activity. Decitabine induces cell cycle arrest and apoptosis.

5'-dCMPS is an analogue of 5'-dCMP and can act as a potential substrate, competitive inhibitor, or modulator for enzymes interacting with 5'-dCMP.

Torcitabine is useful against the hepatitis B virus.

dCMP disodium (2'-Deoxycytidine 5'-monophosphate disodium) is a nucleotide that is widely found in cells and is one of the important intermediates in DNA synthesis and repair. dCMP disodium (2'-Deoxycytidine 5'-monophosphate disodium) is an inhibitor of the DNA synthesis and repair process.

2'-Deoxy-N4-methylcytidine (N(3)-Methyl-2'-deoxycytidine) is a purine nucleoside analog with potential antitumor activity for the study of apoptosis.

dCTPαS sodium is a labeled and modified deoxyoligonucleotide (dNTP) that can release pyrophosphate and generate fluorescence during gene synthesis and sequencing, so it has special application value.

5-fluoro-dCTP sodium is a fluorinated pyrimidine dNTP that serves as a substrate for incorporating a fluorine modification into specific DNA sequences through primer extension catalyzed by Pwo polymerase (PEX).

Cyanine 3-dCTP is a nucleotide labeled with Cy3, used for DNA synthesis.

5-Iodo-dCTP serves as an excellent substrate for DNA polymerase and is utilized in DNA synthesis.

3'-O-Acetyl-2'-deoxycytidine-5'-O-triphosphate (3'-O-Ac-dCTP) tetrasodium is a nucleotide triphosphate derivative that could be useful in DNA synthesis and nucleoside drug design. It can serve as an inhibitor of chain elongation reactions, functioning as either a terminator or a biochemical probe.

4'-Ethynyl-2'-deoxycytidine is an anticancer nucleoside used in research on acute lymphoblastic leukemia and diffuse large B-cell lymphoma.