cycle

Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, exhibiting antinociceptive, anti-inflammatory, and antioxidant activities in different research models.

Oxaloacetic acid, also known as oxosuccinic acid or oxalacetic acid, is a four-carbon dicarboxylic acid appearing as an intermediate of the citric acid cycle. In vivo, oxaloacetate (the ionized form of oxaloacetic acid) is formed by the oxidation of L-mal

Bz-RS-ISer(3-Ph)-Ome (Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate) is a paclitaxel derivative that inhibits the HSV replication cycle at low cytotoxicity, blocks mitosis in Vero cells, affects the size of M-MSV-induced tumors, and influences the immune response by inhibiting PHA-induced proliferation of T lymphocytes.

Samuraciclib hydrochloride (ICEC0942 hydrochloride) is a potent, selective, ATP competitive and oral active CDK7 inhibitor with IC50 of 41 nM. The selectivity of Samuraciclib hydrochloride is 45-, 15-, 230- and 30-fold higher than CDK1, CDK2 (IC50 is 578 nM), CDK5 and CDK9 respectively. Samuraciclib hydrochloride inhibits the growth of breast cancer cell lines with GI50 values between 0.2-0.3 μM. Samuraciclib hydrochloride has anti-tumor effects.

JAK2 inhibitor G5-7 (JAK2 inhibitor G5-7) is an orally active JAK2 inhibitor, selectively inhibits JAK2–mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3 by binding to JAK2. G5-7 has the potential for glioma study

Crolibulin (EPC2407) is an inhibitor of small molecule tubulin polymerization.

OTS514 (OTS514 Hydrochloride) is a potent TOPK inhibitor. OTS514 exhibits a growth-suppressive effect on small cell lung cancer. OTS514 effectively suppressed the growth of SCLC cell lines (IC50: 0.4 ~ 42.6 nM). Treatment with OTS514 suppressed forkhead box protein M1 (FOXM1) activity. OTS514 treatment reduced CD90-positive SCLC cells and showed a higher cytotoxic effect against lung sphere-derived CSC-like SCLC cells.

Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-kit, K-ras and Bcl-2.

CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM, 28-fold greater selectivity for Akt2 than the closely related PKA kinase.

Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selected cancer cell lines, A549, MCF-7, Ca Ski, and HT-29.

Picrocrocin is a natural product

Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1). Scoulerine a potent antimitotic compound that inhibits proliferation, arrests cell cycle, and induces apoptosis in cancer cells.

EBV lytic cycle inducer-1 is an iron chelate analogue that induces the lytic cycle of EBV.

Jasmacyclen is a compound in which has an aroma.

Decacyclene is a biochemical.

Methanesulfonato(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)(2'-methylamino-1,1'-biphenyl-2-yl)palladium(II) is a useful organic compound for research related to life sciences and the catalog number is T67241.

SingaCycle(TM)-A1 is a useful organic compound for research related to life sciences and the catalog number is T67250.

Cycleanine has potent antibacterial, antifungal, antiplasmodial, and cytotoxic activities.

Hexacyclen, also referred to as cycloalkene, is an organic compound characterized by its distinct macrocyclic structure encompassing six nitrogen-containing rings. This compound is primarily utilized as a chelating agent in both chemistry and biochemistry fields for its proficiency in binding metal ions. Additionally, Hexacyclen serves as an inhibitor of specific diseases, including cancer, and plays a significant role in biochemistry for the selective binding of metal ions within proteins or enzymes to facilitate the study of their structure and functionality. Despite its impressive attributes, the compound's considerable size and intricate structure limit its use in everyday products or applications.

Cyclen (1,4,7,10-tetraazacyclododecane) is a macrocycle capable of selectively binding cations that used as a ligand in chemistry for instance with chemicals used in MRI contrast agents.

Tricyclene, a monoterpene identified in various conifers such as Abies, Pinus, Picea, and Tsuga, exhibits notable presence across these species.

Bromocyclen, an insecticide, has been detected in the muscle tissues of rainbow trout from Danish fisheries and in three types of fish (Gudgeon, Crucian carp, and Pike) from the Stör River in northern Germany. Concentrations found range from 0.09 to 1.23 mg kg of fat.

Tris-BOC-cyclen is a bifunctional chelating agent. Bifunctional chelating agents can be utilized to securely attach radioactive metals to the carrier section of radiopharmaceuticals.

Bis-Cbz-cyclen is a bifunctional chelating agent used to stably attach radioactive metals to the carrier components of radiopharmaceuticals.