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coagulation cascade

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
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Melagatran
T11994159776-70-2In house
Melagatran is an orally available, direct synthetic thrombin inhibitor that does not require endogenous cofactors other than thrombin and does not significantly interact with any other enzymes in the coagulation cascade or with the fibrinolytic enzymes.
  • $540
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Prothrombin (474-477) [Mus musculus]
T22676
Prothrombin (coagulation factor II) is produced in the liver and is post-translationally modified in a vitamin K-dependent reaction that converts ten glutamic acids on prothrombin into gamma-carboxyglutamic acid. Prothrombin is proteolytically cleaved to
  • $115
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Cenvacibart
T9901A-8823008610-21-4
Cenvacibart is a monoclonal antibody with anticoagulant properties, targeting human coagulation factor XI (F11). It inhibits the function of factor XI in the coagulation cascade, reducing thrombus formation. Cenvacibart shows promise for research in thrombotic diseases.
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