cell wall assembly

Cephalexin (Cephacillin) is a cephalosporin antibiotic.

MreB Perturbing Compound A22 hydrochloride is an effective inhibitor of MreB, a bacterial actin-like protein. It disrupts cell wall assembly and causes morphological changes, used for bacterial morphogenesis and antibiotic research.

MurF-IN-1 is an antibacterial agent and a potent inhibitor of S. pneumoniae MurF ligase (pIC50 = 5.19). It disrupts cell wall assembly by interfering with peptidoglycan synthesis.

Poacic Acid is a plant-derived stilbenoid exhibiting antifungal activity by localizing to the yeast cell wall and disrupting the production and assembly of β-1,3-glucan in fungal cell walls. It shows fungicidal activity against Saccharomyces cerevisiae and plasma membrane-compromised Candida albicans mutants [1].

β-1,3-Glucan is a major constituent of all characterized fungal cell walls, comprising 30% to 80% of wall mass, and β-1,3-Glucan exists as a branched polymer in the cell wall, with branches connected via β-1,6 linkages, enabling investigation into fungal structural biology, cell wall assembly, immunomodulation, and antifungal therapeutic targeting.