Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • Endogenous Metabolite
    (1)
  • Others
    (21)
Filter
Search Result
Results for "

c24 dihydro ceramide

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    25
    TargetMol | Activity
  • Natural Products
    3
    TargetMol | inventory
  • Isotope Products
    2
    TargetMol | natural
C24 dihydro Ceramide (d18:0/24:0)
T358106063-36-1
C24 dihydro Ceramide is a sphingolipid that has been found in the stratum corneum of human skin.[1] It is found in higher concentrations in female sebum compared to male sebum.[2] C24 dihydro Ceramide levels positively correlate with cytotoxicity in CCRF-CEM, MOLT-4, COG-LL-317h, and COG-LL-332h T cell acute lymphoblastic leukemia (ALL) cell lines.[4] Levels of C24 dihydro ceramide are increased by 149.49-fold in dihydroceramide desaturase 1 (DEGS1) knockdown UM-SCC-22A human head and neck squamous carcinoma cells in vitro.[4] C24 dihydro Ceramide levels are also increased in INS-1 β-cells incubated with glucose and palmitate.[5]
  • $598
7-10 days
Size
QTY
C24:1 1-Deoxyceramide (m18:1/24:1(15Z))
T850311246298-58-7
  • Inquiry Price
8-10 weeks
Size
QTY
C24 (2'(R)-hydroxy) dihydro Ceramide (d18:0/24:0)
T85065164989-36-0
  • Inquiry Price
8-10 weeks
Size
QTY
C24:1 dihydro 1-Deoxyceramide (m18:0/24:1)
T850701246298-60-1
  • Inquiry Price
8-10 weeks
Size
QTY
C24 dihydro 1-Deoxyceramide (m18:0/24:0)
T382841645269-63-1
C24 dihydro 1-Deoxyceramide (m18:0/24:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 C24 dihydro 1-Deoxyceramide (m18:0/24:0) has been found in mouse embryonic fibroblasts (MEFs) following application of 1-deoxysphinganine alkyne or 1-deoxysphinganine-d3.3 It has also been found in mouse brain, spinal cord, and sciatic nerve at one, three, and six months of age.4 |1. Steiner, R., Saied, E.M., Othman, A., et al. Elucidating the chemical structure of native 1-deoxysphingosine. J. Lipid Res. 57(7), 1194-1203 (2016).|2. Alecu, I., Othman, A., Penno, A., et al. Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathway. J. Lipid Res. 58(1), 60-71 (2017).|3. Alecu, I., Tedeschi, A., Behler, N., et al. Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction. J. Lipid. Res. 58(1), 42-59 (2017).|4. Schwartz, N.U., Mileva, I., Gurevich, M., et al. Quantifying 1-deoxydihydroceramides and 1-deoxyceramides in mouse nervous system tissue. Prostaglandins Other Lipid Mediat. 141, 40-48 (2019).
  • $292
Backorder
Size
QTY
3-Oxo-4-benzyl-3,4-dihydro-1H-pyrrolo [2,1-c] oxazine-6-methylal
TN664160026-28-0
3-Oxo-4-benzyl-3,4-dihydro-1H-pyrrolo [2,1-c] oxazine-6-methylal is a natural product for research related to life sciences. The catalog number is TN6641 and the CAS number is 60026-28-0.
  • $390
Backorder
Size
QTY
C-6 NBD-dihydro-Ceramide
T82796114301-95-0
C-6 NBD-dihydro-Ceramide, a biologically active, fluorescent analog of short-chain ceramides, features membrane permeability.
  • Inquiry Price
8-10 weeks
Size
QTY
C17 dihydro Ceramide (d18:0/17:0)
T852791388156-40-8
  • Inquiry Price
8-10 weeks
Size
QTY
C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))
T38285151057-28-2
C24:1 3'-sulfo Galactosylceramide (d18:1 24:1(15Z)) is the predominant sulfate analog in the mature myelin sheath. C24:1 3'-sulfo Galactosylceramide (d18:1 24:1(15Z)) interacted with C-type lectin and immunoglobulin-like receptors to give the highest affinity for LMIR5. Galactosylceramide (d18:1 24:1(15Z)) induces MCP-1 production by basophils, which activates NFAT by increasing LMIR5, but not mast cells .C24:1 3'-sulfo Galactosylceramide (d18:1 24:1(15Z)) binds in vitro to CD1d binding and increased the proliferation of free mouse splenocytes.
  • $1,760
Backorder
Size
QTY
10,11-Dihydro-24-hydroxyaflavinine
TN2564171569-81-6
10,11-Dihydro-24-hydroxyaflavinine is a natural product for research related to life sciences. The catalog number is TN2564 and the CAS number is 171569-81-6.
  • $950
Backorder
Size
QTY
C12((±)-2'-hydroxy) dihydro Ceramide (d18:0/12:0)
T852762377379-54-7
  • Inquiry Price
8-10 weeks
Size
QTY
C16((±)-2'-hydroxy) dihydro Ceramide (d18:0/16:0)
T85175190249-36-6
  • Inquiry Price
8-10 weeks
Size
QTY
C24:1 Ceramide-d7
TMIH-01341840942-16-6
C24:1 Ceramide-d7 is a deuterated compound of C24:1 Ceramide.
  • -$2
7-10 days
Size
QTY
6,7-Dihydro-2H-cyclopenta[c]pyridazin-3(5H)-one
T60118122001-78-9
6,7-Dihydro-2H-cyclopenta[c]pyridazin-3(5H)-one (2H,3H,5H,6H,7H-cyclopenta[c]pyridazin-3-one) is an intermediate used to synthesize Pyridazine derivatives
  • $50
Backorder
Size
QTY
C16 dihydro Ceramide (d18:0/16:0)
T374545966-29-0
C16 dihydro Ceramide (d18:0 16:0) (Cer(d18:0 16:0)) is a precursor for the synthesis of ceramides, induces autophagy in the perinuclear region, and can be used to study cell membrane stability and neurological diseases.
  • $249
7-10 days
Size
QTY
C24 Ceramide-d7
TMIH-01331840942-15-5
C24 Ceramide-d7 is a deuterated compound of C24 Ceramide.
  • -$2
7-10 days
Size
QTY
C24 Phytosphingosine (t18:0/24:0)
T3829134437-74-6
C24 Phytosphingosine (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C24 Phytosphingosine (t18:0/24:0) is composed of a phytosphingosine backbone amine-linked to a C24 fatty acid chain. It has been used with other ceramides to create stratum corneum substitutes to study percutaneous penetration and psoriasis in vitro. In a stratum corneum model of healthy skin, the incorporation of long-chain-containing phytoceramides, such as C24 phytosphingosine (t18:0/24:0), increases permeability of the membrane in comparison with incorporation of dihydroceramides.
  • $185
35 days
Size
QTY
3-Chloro-6,11-dihydro-6-methyl-5,5,11-trioxodibenzo[c,f][1,2]thiazepine
T6590126638-53-9
3-Chloro-6,11-dihydro-6-methyl-5,5,11-trioxodibenzo[c,f][1,2]thiazepine is a useful organic compound for research related to life sciences. The catalog number is T65901 and the CAS number is 26638-53-9.
    7-10 days
    Inquiry
    3-(6-Chloro-1-oxo-1,3-dihydro-2H-pyrrolo[3,4-c]pyridin-2-yl)piperidine-2,6-dione
    T64655
    3-(6-Chloro-1-oxo-1,3-dihydro-2H-pyrrolo[3,4-c]pyridin-2-yl)piperidine-2,6-dione is a useful organic compound for research related to life sciences and the catalog number is T64655.
      7-10 days
      Inquiry
      4-Amino-1,3-dihydro-1-[(6-methyl-3-pyridinyl)methyl]-6-   [(tetrahydro-2H-pyran-4-yl)methoxy]-2H-imidazo[4,5-c]-pyridin-2-one
      TNU08921114529-49-5
      Drugs and Inhibitors; toll-like receptor (TLR) agonist
      • Inquiry Price
      7-10 days
      Size
      QTY
      C2 Dihydro Ceramide (d18:0/2:0)
      T8438313031-64-6
      C2 Dihydro Ceramide (d18:0 2:0) (C2 Dihydroceramide) is a short-chain ceramide that is a precursor of ceramide synthesis and stimulates ABCA1-mediated cholesterol efflux.
      • $365
      In Stock
      Size
      QTY
      C18 dihydro Ceramide (d18:0/18:0)
      T358072304-80-5
      C18 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C18 ceramide that lacks the 4,5-trans double bond. [1] Increased C18 dihydroceramide lipid levels lead to increased triacylglycerol storage and autophagosome accumulation as well as upregulation of the fibrosis markers α-SMA and FGF2 in Chang and LX-2 liver cells. C18 dihydro Ceramide is elevated in the plasma of pre-diabetics up to 9 years prior to the onset of type 2 diabetes. [2] It is also elevated in the skin of patients with lesional atopic dermatitis.[3]
      • $534
      7-10 days
      Size
      QTY
      6-(β-D-5-O-(4,4’-Dimethoxytrityl)-2-deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one
      TNU1296126128-43-6
      Nucleoside Derivatives - Bi-/Tricyclic nucleosides; Protected nucleosides w/NH2/OH open
      • Inquiry Price
      7-10 days
      Size
      QTY
      C24-Ceramide
      T8473334435-05-7
      C24-Ceramide, a sphingolipid utilized in the composition of lipid membranes, induces time-dependent modifications in membrane properties and promotes membrane reorganization [1] [2].
      • Inquiry Price
      8-10 weeks
      Size
      QTY
      C6 dihydro Ceramide (d18:0/6:0)
      T85187171039-13-7
      • Inquiry Price
      8-10 weeks
      Size
      QTY