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c24 dihydro ceramide

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  • Inhibitors & Agonists
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C24 dihydro Ceramide (d18:0/24:0)
Cer(d18:0 24:0)
T358106063-36-1
C24 dihydro Ceramide is a sphingolipid that has been found in the stratum corneum of human skin.[1] It is found in higher concentrations in female sebum compared to male sebum.[2] C24 dihydro Ceramide levels positively correlate with cytotoxicity in CCRF-CEM, MOLT-4, COG-LL-317h, and COG-LL-332h T cell acute lymphoblastic leukemia (ALL) cell lines.[4] Levels of C24 dihydro ceramide are increased by 149.49-fold in dihydroceramide desaturase 1 (DEGS1) knockdown UM-SCC-22A human head and neck squamous carcinoma cells in vitro.[4] C24 dihydro Ceramide levels are also increased in INS-1 β-cells incubated with glucose and palmitate.[5]
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7-10 days
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C24 (2'(R)-hydroxy) dihydro Ceramide (d18:0/24:0)
(R)-2'-hydroxy Ceramide (d18:0 24:0), N-(R)-α-C24 dihydro Ceramide (d18:0 24:0), N-(R)-α-hydroxytetracosanoyl-D-erythro-Dihydrosphingosine, (R)-2'-hydroxy Cer(d18:0 24:0)
T85065164989-36-0
C24 (2'(R)-hydroxy) dihydro Ceramide (d18:0 24:0) is a lipid molecule that can be used in life science related research. The CAS number of C24 (2'(R)-hydroxy) dihydro Ceramide (d18:0 24:0) is 164989-36-0.
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8-10 weeks
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C24 dihydro 1-Deoxyceramide (m18:0/24:0)
C24 dihydro 1-Deoxyceramide (m18:0 24:0)
T382841645269-63-1
C24 dihydro 1-Deoxyceramide (m18:0/24:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 C24 dihydro 1-Deoxyceramide (m18:0/24:0) has been found in mouse embryonic fibroblasts (MEFs) following application of 1-deoxysphinganine alkyne or 1-deoxysphinganine-d3.3 It has also been found in mouse brain, spinal cord, and sciatic nerve at one, three, and six months of age.4 |1. Steiner, R., Saied, E.M., Othman, A., et al. Elucidating the chemical structure of native 1-deoxysphingosine. J. Lipid Res. 57(7), 1194-1203 (2016).|2. Alecu, I., Othman, A., Penno, A., et al. Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathway. J. Lipid Res. 58(1), 60-71 (2017).|3. Alecu, I., Tedeschi, A., Behler, N., et al. Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction. J. Lipid. Res. 58(1), 42-59 (2017).|4. Schwartz, N.U., Mileva, I., Gurevich, M., et al. Quantifying 1-deoxydihydroceramides and 1-deoxyceramides in mouse nervous system tissue. Prostaglandins Other Lipid Mediat. 141, 40-48 (2019).
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C24:1 1-Deoxyceramide (m18:1/24:1(15Z))
N-tetracosenoyl-1-deoxy-4,5-dihydro-Sphingosine, C24:1(15Z) 1-Deoxyceramide, C24:1 Ceramide (m18:1 24:1(15Z)), Cer(m18:1 24:1(15Z))
T850311246298-58-7
C24:1 1-Deoxyceramide (m18:1 24:1(15Z)) is a lipid molecule that can be used in life science related research. The CAS number of C24:1 1-Deoxyceramide (m18:1 24:1(15Z)) is 1246298-58-7.
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8-10 weeks
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C24:1 dihydro 1-Deoxyceramide (m18:0/24:1)
Cer(m18:0 24:1), C24:1 deoxyDHCeramide, C24:1 dihydro Ceramide (m18:0 24:1), C24:1deoxyDHCer, ​C24:1 deoxy Dihydroceramide, N-tetracosenoyl-1-deoxy-Sphinganine
T850701246298-60-1
C24:1 dihydro 1-Deoxyceramide (m18:0 24:1) is a lipid molecule that can be used in life science related research. The CAS number of C24:1 dihydro 1-Deoxyceramide (m18:0 24:1) is 1246298-60-1.
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8-10 weeks
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