biloba

Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.

1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 inhibitor and may be a useful lead

Sciadopitysin may prevent the development of diabetic osteopathy, it exerts its therapeutic effects via upregulation of mitochondrial biogenesis.Sciadopitysin shows protective effects on antimycin A-induced toxicity in osteoblastic MC3T3-E1 cells, it may

Ginkgo Biloba Extract (Standard) is the standard reference of Ginkgo Biloba Extract, suitable for quantitative analysis, quality control and biochemical research. Ginkgo Biloba Extract is a natural active ingredient extracted from ginkgo leaves. It maintains the structural and functional homeostasis of mitochondria, regulates the expression of Bcl-2 family proteins, blocks caspase cascade activation, and thereby alleviates neuronal apoptosis mediated by oxidative stress. Meanwhile, it upregulates SKP2 expression, inhibits non-Beclin1-dependent autophagy pathways, and ameliorates testicular tissue injury. In animal experimental models, it exerts protective effects on multiple types of neuronal damage and alleviates behavioral sensitization in rats. Against β-amyloid (Aβ)-mediated neurotoxicity, Ginkgo Biloba Extract produces multiple antagonistic effects: inhibiting Aβ-induced abnormal glucose uptake, ROS accumulation, AKT signaling disorder and mitochondrial dysfunction, regulating JNK and ER1/2 signaling pathways, blocking neuronal apoptosis, and suppressing the aggregation and formation of Aβ oligomers. Current research confirms that Ginkgo Biloba Extract has potential research value and application prospects in various neurological and tissue injury diseases including cerebral insufficiency, testicular injury, Alzheimer's disease, Parkinson's disease, multi-infarct dementia, stroke, traumatic brain injury and amyotrophic lateral sclerosis.

Bilobalide (Standard) is a reference standard for research and analysis in studies involving Bilobalide. Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.

Ginkgolide B (BN-52021) is a PAFR antagonist(IC50=3.6 μM) isolated from Ginkgo biloba.

Sequoiaflavone is a biflavone isolated from Ginkgo biloba.

Ginkgolide A (BN-52020) is a highly active PAF antagonist cage molecule isolated from Ginkgo biloba leaves, showing potential in various inflammatory and immunological disorders.

1. ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponectin production. 2. Isoginkgetin has anti-tumor activity, the mechanistic basis is splicing inhibition , thus, pre-mRNA splicing inhibitors may represent a novel avenue for development of new anti-cancer agents.3. Isoginkgetin can inhibit tumor cell invasion by regulating phosphatidylinositol 3-kinase/Akt-dependent matrix metalloproteinase-9 expression. 4. Isoginkgetin (0.3mg/kg ip for 3d) can reduce the level of O2·- in plasma and erythroeyte and sometimes increase the activity of SOD in anoxic rats, the action being stronger than aspirin.

Antioxidant Agent-18 (Compound 5), a flavonol glycoside derived from Ginkgo biloba, exhibits antioxidant properties through its ability to scavenge DPPH radicals (IC50: 15.8 μM) and reduce cytochrome c (IC50: 14.7 μM).

ISOGINKGETIN (Standard) is a reference standard for research and analysis in studies involving ISOGINKGETIN. 1. ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponectin production. 2. Isoginkgetin has anti-tumor activity, the mechanistic basis is splicing inhibition , thus, pre-mRNA splicing inhibitors may represent a novel avenue for development of new anti-cancer agents.3. Isoginkgetin can inhibit tumor cell invasion by regulating phosphatidylinositol 3-kinase/Akt-dependent matrix metalloproteinase-9 expression. 4. Isoginkgetin (0.3mg/kg ip for 3d) can reduce the level of O2·- in plasma and erythroeyte and sometimes increase the activity of SOD in anoxic rats, the action being stronger than aspirin.

Ginkgolide A (Standard) is a reference standard for research and analysis in studies involving Ginkgolide A. Ginkgolide A (BN-52020) is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and immunological disorders.

Ginkgolide B (Standard) is a reference standard for research and analysis in studies involving Ginkgolide B. Ginkgolide B (BN-52021) is a PAFR antagonist(IC50=3.6 μM) isolated from Ginkgo biloba.

4'-O-Methylochnaflavone is a biflavonoid compound extracted from the leaves of Ginkgo biloba L., which inhibits lymphocyte proliferation induced by Con A or LPS.

Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside (Quercetin 3-O-beta-(6''-p-coumaroyl)glucopyranosyl(1->2)-alpha-L-rhamnopyranoside) is a compound extracted from the leaves of Ginkgo biloba with notable antioxidant properties.

(E/Z)-Ginkgolic Acid C17:2 (Ginkgolic Acid C17:2) is a natural product extracted from Ginkgo biloba that targets human dihydroorotate dehydrogenase (DHODH).

Ginno is a natural product Ginkgo biloba L.

4'-O-Methylpyridoxine (MPN) is a vitamin-like compound discovered from Ginkgo biloba with antioxidant activity and cytotoxicity.

Stigmastan-3β-ol is a steroid compound isolated from Tinospora sinensis and Ginkgo biloba L., with antibacterial bioactivity.

Deacetylescin Ia (compound 12) is an anti-hyperglycemic deacetylated saponin extracted from de-bittered Ginkgo biloba leaves by deacetylation at position C-22. In mice glucose tolerance tests, Deacetylescin Ia (100mg/kg) demonstrated an ability to inhibit the increase in blood sugar levels.