beta-1,3-glucan

Laminaran is a β-1,3-glucan isolated from brown algae, often serving as a typical ligand for Dectin-1. It possesses anti-cancer, immune-modulating, and radiation-protective properties. Laminaran can be catalyzed by glucanase. In in vitro and in vivo experiments, Laminaran has demonstrated anti-tumor activity and may be used for severe cancers.

Micafungin sodium (FK 463) is the sodium salt form of micafungin, a semi-synthetic echinocandin derived from a natural product of the fungus Coleophoma empetri with antifungal activity.

Caspofungin Acetate (MK 0991) is the acetate salt of an antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. This agent is active against Aspergillus and Candida species.

L 687781 is a natural product that is a member of the papulacandin family. L 687781 is also a 1,3-beta-glucan synthesis inhibitor.

Tetrahydroechinocandin B is a cyclic hexapeptide containing a fatty acyl side chain. It also inhibits 1,3-beta-D-glucan synthesis.

Echinocandin B is a cyclic hexapeptide echinocandin antibiotic from Aspergillus nidulans var. echinulatus . It attacks the cell wall of fungi by inhibiting beta-1,3-glucan synthesis.

Caspofungin is a cyclic lipopeptide echinocandin and beta-(1,3)-D-glucan synthase inhibitor that is used to treat internal or systemic mycoses.

Enfumafungin is a triterpenoid glycoside isolated from endophytic fungi, exhibiting antifungal activity against Candida and Aspergillus species by inhibiting (1,3)-β-D-glucan synthesis.

Pneumocandin B2 is a lipopeptide antibiotic with potent anti-candidal effects, demonstrating inhibition of 1,3-beta-D-glucan synthesis in vitro, with an IC50 ranging from 0.07 to 0.5 μg/mL.

Pneumocandin A2 is a lipopeptide antibiotic with potent antifungal activity against Candida species. It inhibits 1,3-beta-D-glucan synthesis in vitro, with an IC50 ranging from 0.07 to 0.5 μg/mL.

Pneumocandin A3 is a lipopeptide antibiotic with potent antifungal activity against Candida species, exhibiting inhibitory effects on 1,3-beta-D-glucan synthesis in vitro, with an IC50 range of 0.07-0.5 μg/mL.