benzoxazolone

ARN14974 is a benzoxazolone carboxamide. ARN14974 is a potent inhibitor of acid ceramidase with IC50 of 79 nM[1].

2-Benzoxazolinone (2-Hydroxybenzoxazole) is found in cereals and cereal products. 2-Benzoxazolinone is found in rye seedlings.

1. Coixol (MBOA) acts as a central muscle relaxant with an anti-convulsant effect. 2. Coixol interacts with the pituitary to stimulate reproduction in voles. 3. Coixol has the ability to interact with FSH to stimulate follicular development and increase ovulation. 4. Coixol can regulate gene expression, production and secretion of mucin, by directly acting on airway epithelial cells.

6-Hydroxy Chlorzoxazone is the major metabolite of the muscle relaxant chlorzoxazone. 6-Hydroxy Chlorzoxazone is a chlorinated benzoxazolone generated by metabolism via the CYP2E1 enzyme in the liver. 6-Hydroxy Chlorzoxazone serves as a reliable marker for assessing CYP2E1 metabolic activity and is used as a reference standard in biochemical research.

sEH inhibitor-14, a benzoxazolone-5-urea analogue, acts as an efficient soluble Epoxide Hydrolase (sEH) inhibitor, demonstrating significant activity with an IC50 value of 0.39 nM.