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aicar monophosphate

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  • Inhibitors & Agonists
    4
    TargetMol | Inhibitors_Agonists
AICAR monophosphate
Z-nucleotide, AICA riboside, Aica ribonucleotide, Acadesine 5'-monophosphate
T211953031-94-5In house
AICAR monophosphate (Aica ribonucleotide) is a purine precursor with antineoplastic activity and can be used in studies about type 2 diabetes.
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6-8 weeks
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ATIC-IN-2
T20443367095-44-7
ATIC-IN-2 (Compound 1) is a competitive inhibitor of the bifunctional enzyme AICAR Tfase IMPCH (ATIC), binding to inosine monophosphate cyclohydrolase (IMPCH) with a Ki of 0.13 μM.
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10-14 weeks
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ATIC-IN-1 acetate
T78159
ATIC-IN-1 acetate is an inhibitor of aminoimidazole-carboxamide ribonucleotide transformylase inosine monophosphate cyclohydrolase (ATIC) with potential anti-tumor activity. It inhibits AICAR Tfase by disrupting ATIC homo-dimerization.
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ATIC-IN-1
T829501402453-15-9
ATIC-IN-1 (compound 14) is an inhibitor targeting the dimerization of Aminoimidazole carboxamide ribonucleotide transformylase inosine monophosphate cyclohydrolase (ATIC), with a K i of 685 nM. This dimerization is crucial for the enzyme's AICAR transformylase function. Additionally, ATIC-IN-1 exhibits anti-tumor properties by reducing cell proliferation and cell division rates [1].
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8-10 weeks
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