aglycone

Silvestrol aglycone (enantiomer) is a cyclopenta benzofuran core phenol.

Silvestrol aglycone is an analogue of Silvestrol, inhibits protein translation initiation in cancer cells(EC50s of 10 and 200 nM for myc-LUC and tub-LUC luciferase reporter protein translation, respectively), with nti-cancer activity.

7-Deoxyadriamycinol aglycone is an adriamycin metabolite.

Spinosyn Daglycone (A-83543D aglycone) is an aglycone form of the insecticide Spinosyn D. Unlike Spinosyn D, Spinosyn Daglycone is not harmful to neonate larvae of H. virescens (tobacco budworm) with an LC50 of greater than 64 ppm.

Adriamycin Aglycone, also known as Doxorubicinone, is an oncolytic agent. It is a metabolite of Doxorubicin which binds to the DNA minor-groove.

Aloenin aglycone (compound 13), an inhibitor of NF-κB, can be sourced from aloe exudate. It impedes TNFα-stimulated NF-κB transcriptional activity, showing an IC 50 of 18.7 μM. At a concentration of 10 μM, aloenin aglycone decreases both inducible nitric oxide synthase (iNOS) and intercellular adhesion molecule 1 (ICAM-1) gene expression in HepG2 cells exposed to 10 ng/mL TNFα [1].

IB-96212 aglycone (Compound 2) represents the hydrolyzed form of IB-96212 .

Oleuropein aglycone is a useful organic compound for research related to life sciences and the catalog number is T125057.

Bredinin aglycone is a purine nucleotide analog that can be used to assay the efficiency of purine nucleotide analog catalysts .

Teicoplanin aglycone is an antibacterial glycopeptide antibiotic used in the prophylaxis and treatment of serious infections caused by Gram-positive bacteria, including Enterococcus faecalis and methicillin-resistant Staphylococcus aureus.

Doramectin aglycone is an acid degradation product of doramectin , a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes, and its acid-catalyzed hydrolysis product doramectin monosaccharide . Doramectin undergoes one round of acid-catalyzed hydrolysis to form doramectin monosaccharide which is then hydrolyzed again to remove the remaining saccharide unit and form doramectin aglycone.

Ivermectin B1a aglycone is an acid degradation product produced by hydrolysis of the disaccharide unit of ivermectin. It can inhibit nematode larval development, but does not cause paralytic activity.

Avermectin B1a aglycone is an aglycone form of the anthelmintic and insecticide avermectin B1a . It hyperpolarizes P. crassipes muscle fibers with a minimum active concentration (MAC) value of 0.1 μM. Avermectin B1a aglycone decreases survival of C. elegans (MAC = 0.1 μM). In vivo, avermectin B1a aglycone prevents seizures induced by pentylenetetrazole in mice (ED50 = 43.9 mg/kg) without inducing deficits in rotarod performance.

Burnettramic acid A aglycone is a fungal metabolite and an aglycone form of burnettramic acid A, originally isolated from [A. burnettii], that exhibits anticancer activity. It is cytotoxic to NS-1 murine myeloma cells (IC50 = 8.4 μg/ml) but not to neonatal foreskin fibroblasts (IC50 > 100 μg/ml).

Daturataturin A aglycone is a natural product for research related to life sciences. The catalog number is TN3775 and the CAS number is 904665-71-0.

Plucheoside B aglycone is a natural product for research related to life sciences. The catalog number is TN5385 and the CAS number is 393862-19-6.

Spinosyn Aaglycone ((-)-Spinosyn A aglycon) is the glycosidic form of the insecticide Spinosyn A. It is an acidic degradation product resulting from the hydrolysis of two sugar moieties on Spinosyn A.

Qingyangshengenin (Cynanchagenin) is a steroid used in the preparation of antiepileptic agents.

Momordicoside I aglycone is a natural product

3'-Ethoxy-5,6-dihydrospinosyn J 17-pseudoaglycone is a potent insecticidal derivative of spinosyn. At a concentration of 500 mg/L, it achieves a 100% mortality rate against armyworms, aphids, and red spider mites.

Methyl Hesperidin, a flavanone glycoside (flavonoid) (C28H34O15), is abundant in citrus fruits. Its aglycone form is called hesperetin.

Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis.

Asiatic acid (Dammarolic acid) is the aglycone of asiaticoside used in wound healing with antioxidant, anti-inflammatory, and neuroprotective properties.

(-)-Arctigenin ((-)-Arctigenin) is found in burdock. (-)-Arctigenin is isolated from Cnicus benedictus, Forsythia viridissima, Arctium lappa, Ipomoea cairica and others (CCD). Arctigenin is a lignan found in certain plants of the Asteraceae, including the Greater burdock (Arctium lappa) and Saussurea heteromalla. It has shown antiviral and anticancer effects. It is the aglycone of arctiin.