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Search Results for " aberrations "

10

Compounds

Cat No. Product Name Synonyms Targets
T16832 S18-000003 ROR
S18-000003 is an effective orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t inhibitor (IC50: 29 nM). S18-000003 inhibits IL-17 production.
T4730 Thymidine-5'-monophosphate disodium salt Thymidine 5'-monophosphate disodium salt,TMP DISODIUM SALT Others , Endogenous Metabolite
Thymidine-5'-monophosphate disodium salt (TMP DISODIUM SALT) is found in DNA. In mammalian cells, thymidine deprivation induces chromosome aberrations such as chromatid breaks, chromatid interchanges, and chromosome frag...
T26637 Antipain dihydrochloride Antipain 2HCl,BDBM-32804,BDBM 32804, Antipain,BDBM32804 Protease
Antipain dihydrochloride (Antipain 2HCl) is a protease inhibitor derived from Actinomycetes that exhibits analgesic activity and inhibits X-ray-induced chromosomal aberrations in human lymphocytes.
T5983 O-Phenanthroline 1,10-Phenanthroline MMP , Others
o-Phenanthroline (1,10-Phenanthroline) , a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells.o-Phenanthroline protects mammalian cells from hydrogen peroxide-induced gene m...
T40834 5-Hydroxymethyl-2'-deoxycytidine 5hmdC PARP
5-Hydroxymethyl-2'-deoxycytidine is an oxidized derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA, causing DNA damage reactions, chromosomal aberrations, replication fork damage, and loss of cell viability.5-Hydroxy...
TN1929 Methyl sinapate Others
Methyl sinapate can increase the frequency of cells with chromosome aberrations in the CHO K-1 cells treated with MMC, 4NQO or UV.
T14295 Antipain Others
Antipain is a protease inhibitor isolated from Actinomycetes. Antipain inhibits N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations[1][2].
T70229 Laromustine
Laromustine is a sulfonyl hydrazine prodrug with antineoplastic activity. Laromustine releases the DNA chloroethylating agent 90CE after entering the blood stream; 90CE chloroethylates alkylates the 06 position of guanin...
TN4249 Ilicol Others
Pinocembrin and Ilicol inhibit root growth and show IC50 (root growth) values of 0.199, 14.68, 8.05, 7.69 mM, and 1.22, 2.90, 7.35, 8.07 mM, against P. miliaceum, A. sativa, L. sativa, and R. sativus, respect...
T35993 Epitalon (acetate)
Epitalon is a synthetic tetrapeptide with anti-aging properties.1,2,3,4 Dietary administration of epitalon (0.00001% w/w) reduces levels of lipid peroxidation products in aged D. melanogaster tissue homogenates.1 Epitalo...
TargetMol