T4089

FX1 is an effective and selective BCL6 inhibitor (IC50: 35 μM).

ADTL-SA1215 is a selective SIRT3 activator with SIRT3 deacetylase activity that inhibits the proliferation and migration of human breast cancer MDA-MB-231 cells through the SIRT3-driven autophagy/mitochondrial autophagy signaling pathway, and can be used in the study of triple negative breast cancer.

Bromo-C10-OBn, a PROTAC linker, is utilized in the synthesis of PROTACs.

Estrogen receptor modulator 6 (compound 3a) is a highly specific and potent agonist of the estrogen receptor (ER) β, exhibiting remarkable affinity (K i = 0.44 nM) and impressive 19-fold selectivity for ERβ over ERα, as evidenced by its affinity (K i = 8.4 nM).

PEG2-Cl is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Calmodulin antagonist-1 (W-7) is a calmodulin (CaM) antagonist that effectively inhibits calmodulin-activated Ca 2+ -phosphodiesterase (PDE) with an IC 50 of 28 μM. This compound also competitively inhibits trypsin-treated Ca 2+ -PDE with respect to cyclic GMP, exhibiting an IC 50 of 375 μM and a K i value of 300 μM.

Bromchlorbuterol hydrochloride is a potent β-adrenergic agonist (β-agonist) compound commonly employed in the investigation of pulmonary conditions such as pulmonary disease and asthma.

Lenalidomide-4-aminomethyl is a CRBN ligand derived from Lenalidomide, which is utilized for the recruitment of CRBN protein. By linking Lenalidomide-4-aminomethyl to the ligand, a PROTAC can be formed.

DMHCA is a selective LXR agonist with anti-inflammatory activity, which induces ABCA1 expression and upregulates FASN and SREBP-1alpha gene expression.

2-Chloroacetamide is a multifunctional chemical compound widely applied as a preservative and herbicide for vegetation control in upland and paddy field environments, 2-Chloroacetamide also serves as a biocide in agriculture, adhesives, paints, and coatings. 2-Chloroacetamide additionally exhibiting inhibitory activity against very-long-chain fatty acid elongase, highlighting its relevance across agrochemical, industrial, and biochemical research applications.