T1251

Dicloralurea (DCU) is a veterinary food additive that inhibits methane production in herbicide ruminants.

PAT-1251 is an inhibitor of LOXL2 with IC50s of 10, 0.12, and 0.16 μM for the mouse, rat, and dog and can be used in studies about fibrotic diseases.

PNU-177864 hydrochloride is a potent, selective, and orally active dopamine D3 receptor antagonist that is structurally consistent with a cationic amphiphilic drug (CAD). It induces phospholipidosis in vivo and exhibits antischizophrenic activity.

PNU288034, a potent oxazolidinone antibiotic, demonstrates antimicrobial activity for the prevention and treatment of Gram-negative infections.

PNZ5, an isoxazole-based pan-BET inhibitor, demonstrates potent activity and high selectivity comparable to the established (+)-JQ1, exhibiting a dissociation constant (KD) of 5.43 nM for BRD4(1).

Lenumlostat is an orally available, selective and potent lysyl oxidase-like protein 2 (LOXL2) inhibitor with inhibitory effects on hLOXL2, hLOXL3 and LOXL2 for the study of fibrotic diseases.

Polyinosinic-polycytidylic acid sodium (Poly(I:C) sodium) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5).

Sodium metatungstate (Sodium polyoxotungstate) is a potent inhibitor of ecto-nucleoside triphosphate diphosphohydrolase (NTPDase), with Ki values of 2.58 μM for NTPDase 1, 3.26 μM for NTPDase 3, and 28.8 μM for NTPDase 2.

PAT-1251 Hydrochloride is a potent, selective, and oral inhibitor of lysyl oxidase-like 2 (LOXL2), targeting hLOXL2 and hLOXL3 with IC50 values of 0.71 and 1.17 μM, respectively.

Pterosin B, a type of indanone found in Pteridium aquilinum, is an inhibitor of salt-induced kinase 3 (Sik3) signal transduction. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.

1,3-Diacetoxy-4,6,12-tetradecatriene-8,10-diyne is a useful organic compound for research related to life sciences. The catalog number is T125101 and the CAS number is 29576-66-7.

Pseudolycorine is a useful organic compound for research related to life sciences and the catalog number is T125103.

N-Malonyltryptophan is a useful organic compound for research related to life sciences. The catalog number is T125105 and the CAS number is 29399-11-9.

Heptaibin is a useful organic compound for research related to life sciences. The catalog number is T125107 and the CAS number is 291311-47-2.

Fukugiside is a natural product that can be used as a reference standard. The CAS number of Fukugiside is 29082-55-1.

PNU-248686A is an inhibitor of matrix metalloproteinase (MMP).

Stigmalactam is a useful organic compound for research related to life sciences and the catalog number is T125112.

Cyclo(L-Leu-L-Pro) is a compound from Pseudomonas sesquiterpenes BC42 that exhibits antifungal activity, inhibiting fungal pathogens, the proliferation of Aspergillus flavus, conidial germination, and conidial formation, making it useful for agricultural biocontrol.

Colladin is a natural product that can be used as a reference standard. The CAS number of Colladin is 28691-96-5.

Cyclo(L-Pro-L-Val), a 2,5-diketopiperazine extracted from the fruits of Mycobacterium chiliolyticum AZ2 and Mycobacterium leprae, possesses anti-inflammatory activity and virulence activity against phytopathogenic microorganisms (e.g., R. fascians LMG 3605) and inhibits Gram-positive plant pathogens.Cyclo(L-Pro-L-Val) significantly inhibited IKKα phosphorylation and IκBα and NF-κB activation as well as iNOS and COX-2 activation in a concentration Cyclo(L-Pro-L-Val) significantly inhibited the phosphorylation of IKKα, IKKβ, IκBα, and NF-κB, as well as the activation of iNOS and COX-2 in a concentration-dependent manner, and is a potential therapeutic agent for the treatment of inflammation-related diseases.

DHBOA-Glc is a natural product that can be used as a reference standard. The CAS number of DHBOA-Glc is 28512-70-1.

Nidurufin is a useful organic compound for research related to life sciences. The catalog number is T125124 and the CAS number is 28458-23-3.

Kaempferol 3-rungioside is a useful organic compound for research related to life sciences. The catalog number is T125125 and the CAS number is 28447-29-2.

Urospermal is a useful organic compound for research related to life sciences. The catalog number is T125126 and the CAS number is 28400-14-8.