pol-1-in-1 — TargetMol Chemicals

Search Result

Search Results for " pol-1-in-1 "

Compounds

Cat No.	Product Name	Synonyms	Targets
T4356	POL1-IN-1	Compound 3A	DNA/RNA Synthesis
	POL1-IN-1 (Compound 3A) can effectively inhibit the transcription of RNA polymerase I in the A375 malignant melanoma cell line but has no effect on polymerase II.		DNA/RNA Synthesis
T61720	Pol I-IN-1
	Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibition concentration (IC50) of 0.21 μM [1].
T81431	Pol (476-484), HIV-1 RT Epitope
	Pol (476-484), HIV-1 RT Epitope is a biologically active peptide and represents the dominant HLA A0201-restricted epitope within HIV-1 reverse transcriptase (RT), spanning Pol* residues 476-484. It has been utilized to e...
T74630	RNA polymerase II-IN-1		DNA/RNA Synthesis
	RNA polymerase II-IN-1 (compound 19iv), an amatoxin, selectively inhibits RNA polymerase II (Pol II) with an IC50 of 36.66 nM. It exhibits heightened cytotoxicity towards cancer cells and reduced toxicity in normal cells...		DNA/RNA Synthesis
T74631	RNA polymerase II-IN-2
	RNA polymerase II-IN-2 (compound 20iii), a potent inhibitor of RNA polymerase II (Pol II) with a K i value of 9.5 nM, demonstrates cytotoxicity against cancer cells, exhibiting toxicity levels 2 and 5 times higher than α...
T82758	CDK9-Cyclin T1 PPI-IN-1		CDK
	CDK9-Cyclin T1 PPI-IN-1 (Compound B19) is a selective inhibitor of the CDK9-Cyclin T1 protein-protein interaction (PPI), suppressing cell proliferation in TNBC MDA-MB-231 cells with an IC50 of 0.044 μM and inducing apopt...		CDK