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Search Results for " kcnq2 "

13

Compounds

Cat No. Product Name Synonyms Targets
T9400 KCNQ2/3 activator-1 Others
KCNQ2/3 activator-1 is a Kv7.2/Kv7.3 (KCNQ2/3) potassium channel activator.
T15545 ICA-27243 Potassium Channel
ICA-27243 is less effective at activating KCNQ4 and KCNQ3/Q5. ICA-27243 is a potent and orally active KCNQ2/Q3 potassium channel opener (EC50: 0.38 μM). ICA-27243 also has antiepileptic and anticonvulsant effects.
T3959 ICA-069673 ICA069673 Potassium Channel
ICA-069673 is an activator of KCNQ2/Q3 potassium channel (IC50: 0.69 μM).
T7612 ICA 110381 Potassium Channel
ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy
T8446 QO-40 Potassium Channel
QO-40 is a KCNQ2/3 potassium channels activator.
T28544 RL648_81 Potassium Channel
RL648_81 is a selective activator of KCNQ2/3 channels (EC50 = 190 nM). RL648_81 can be used in studies about neuronal hyperexcitability neurologic disorders.
T78570 XE991 Potassium Channel
XE991 is a novel and selective Kv7 (KCNQ) channel blocker.XE 991 dihydrochloride inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channels, and M-current, and can be used for the study of neurological disease...
T17262 XE 991 dihydrochloride Others , Potassium Channel
XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker. XE 991 dihydrochloride potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current (IC50s: 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, r...
T4030 ML213 CID-3111211 Potassium Channel
ML213 (CID-3111211) is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM, respectively.
T29236 ZTZ240 ZTZ 240,ZTZ-240
ZTZ240, a KCNQ2 K+ channel activator, offers a new target to treat hyperexcitability disorders.
T61086 HN37
HN37 as a potent and chemically stable antiepileptic drug candidate, with an EC 50 of 37 nM for KCNQ2 [1].
T69514 CLE-030
CLE-030 is a KCNQ2 agonist. CLE030 stably binds to the central cavity. Functional analysis, molecular dynamics simulations, and calculations of the potential of mean force revealed that the carbonyl oxygen of CLE030 inf...
T70786 ML252
ML252 is a selective potassium channel inhibitor, specifically targeting the KCNQ2 channel (Kv7.2) with an IC50 value of 69 nM. Additionally, ML252 demonstrates inhibitory activity against Cytochrome P450 isoforms, inclu...
TargetMol