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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T27527 | HBF-0259 | HBF 0259 | Antiviral |
HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells. HBF-0259 had a EC50 of approximately 1.5 microM in a secondary, HBV... | |||
T60898 | HbF inducer-1 | ||
HbF inducer-1 is a fetal hemoglobin inducer which is orally bioavailable. | |||
T21652 | RN-1 dihydrochloride | Histone Demethylase , MAO | |
RN-1 dihydrochloride is an effective and selective irreversible inhibitor of lysine-specific demethylase 1 (LSD1, IC50 = 70 nM). | |||
T19583 | TN1 | Others | |
TN1 is a potent inducer of fetal hemoglobin (HbF). | |||
T40154 | FTX-6058 | ||
FTX-6058 is a potent orally active inhibitor targeting Embryonic Ectoderm Development (EED). It effectively induces HbF protein expression in both cell and murine models. This compound holds significant potential for res... | |||
T73517 | RK-701 | ||
RK-701, a highly selective and non-genotoxic G9a inhibitor, exhibits an IC 50 value of 23-27 nM. It selectively up-regulates HbF, γ-Globin, and BGLT3 expression while down-regulating H3K9me2 expression. Additionally, RK-... | |||
T40155 | FTX-6058 hydrochloride | ||
FTX-6058 hydrochloride is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED), with the ability to induce HbF protein expression in both cell and murine models. This compound is particularly valu... |