ftsz — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T61737	FtsZ-IN-4
	FtsZ-IN-4, an orally active inhibitor of FtsZ (filamenting temperature-sensitive mutant Z), demonstrates remarkable antibacterial activity and favorable pharmaceutical properties. With low cytotoxicity (CC 50 >20 μg/mL) ...
T74788	FtsZ-IN-5
	FtsZ-IN-5 is a potent inhibitor of FtsZ, promoting polymerization while inhibiting its GTPase activity, thereby preventing bacterial division and leading to cell death. It exhibits bactericidal activity without significa...
T74790	FtsZ-IN-7
	FtsZ-IN-7 is a potent inhibitor of FtsZ, enhancing FtsZ polymerization while inhibiting its GTPase activity, therefore disrupting bacterial cell division and culminating in bacterial cell death. It exhibits bactericidal ...
T74791	FtsZ-IN-8
	FtsZ-IN-8, a potent inhibitor of FtsZ, both promotes FtsZ polymerization and inhibits its GTPase activity, leading to the inhibition of bacterial division and subsequent bacterial cell death. This compound exhibits bacte...
T63370	FtsZ-IN-2
	FtsZ-IN-2 is an inhibitor of the bacterial cytokinin FtsZ and has an inhibitory effect on GTPase activity. ftsZ-IN-2 exhibited anti-staphylococcal effects with MIC values of 2 μg/ml for both MSSA and MRSA.
T63552	FtsZ-IN-1
	FtsZ-IN-1 is a potent FtsZ inhibitor with a quinoline ring and has a strong inhibitory effect on Gram-positive bacteria (MIC: 0.5-8 μg/mL).FtsZ-IN-1 enhances FtsZ polymerization and significantly promotes cell elongation...
T74789	FtsZ-IN-6
	FtsZ-IN-6 is a potent inhibitor of FtsZ, enhancing its polymerization while inhibiting its GTPase activity, thereby obstructing bacterial cell division and causing bacterial cell death. This compound exhibits bactericida...
T7439	3-Methoxybenzamide	3-MBA	PARP , Antibacterial , Transferase
	3-Methoxybenzamide (3-MBA) is a competitive inhibitor of poly(ADP-ribose) synthetase.		PARP , Antibacterial , Transferase
T8211	(±)-Decursinol	3',4'-dihydro-3'-hydroxy-Xanthyletin	Others , Antibacterial
	(±)-Decursinol (3',4'-dihydro-3'-hydroxy-Xanthyletin) is a natural product from Angelica gigas.		Others , Antibacterial
T25214	CCR-11	CCR11,CCR 11	Antibiotic
	CCR-11 is a tannin-containing derivative with antimicrobial activity. CCR-11 inhibits the proliferation of B. subtilis and HeLa cells. CCR-11 inhibits bacterial proliferation and bacterial cytoplasmic division by inhibit...		Antibiotic
T21831	UCM05	G28UCM	Fatty Acid Synthase
	UCM05 (G28UCM) is a potent inhibitor of fatty acid synthase (FASN) with efficacy against HER2+ breast cancer xenografts, including in cell lines resistant to anti-HER2 drugs [1]. Additionally, it functions as an inhibito...		Fatty Acid Synthase
T9534	Compound GK02084(SC)		Others
	Compound GK02084(SC) may have activity against the GTP site of Bs‐FtsZ.		Others
T24599	PC170942 Sodium	PC170942 Sodium salt
	PC170942 Sodium is a water-soluble bacterial cytokinesis inhibitor that acts by inhibiting FtsZ.
T61274	PC190723
	PC190723 (Compound 2), an inhibitor of the FtsZ bacterial cell division protein, demonstrates potent efficacy with an IC50 value of 55 ng/ml. Additionally, it showcases notable anti-staphylococcal activity, characterized...
T39857	8-Br-GTP	8-Bromoguanosine-5'-triphosphate,8-Br-GTP
	8-Br-GTP, an analog of GTP, functions as both a competitive inhibitor of FtsZ polymerization and GTPase activity (with a K i value of 31.8 μM). Moreover, it is capable of facilitating nucleic acid modification.
T28305	PC58538	PC-58538,PC 58538
	PC58538 is an inhibitor of FtsZ protein, a important role in the division machinery of bacterial cells.
T63116	TXA6101
	TXA6101 is an inhibitor of the bacterial protein FtsZ (filamentous temperature sensitive protein Z). TXA6101 inhibits bacterial division and has an MIC of 1 μg/mL against MRSA isolates expressing either the G193D or G196...
T69376	Viriditoxin
	Viriditoxin is a secondary metabolite isolated from Aspergillus viridinutans that has been shown to inhibit FtsZ, the bacterial homologue of eukaryotic tubulin.
T83814	8-Bromoguanosine-5'-O-triphosphate sodium	8-bromo GTP
	8-Bromoguanosine-5'-O-triphosphate, a derivative of guanosine 5'-triphosphate (GTP) - the energy substrate for protein synthesis and gluconeogenesis, acts as an inhibitor of the E. coli GTPase FtsZ with an inhibition con...
T35437	(-)-Viriditoxin
	(-)-Viriditoxin is a mycotoxin originally isolated from A. viridinutans that has antibacterial and antiproliferative activity. It is active against methicillin-sensitive and -resistant S. aureus (MSSA and MRSA, respectiv...