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Search Results for " foxp3 "

12

Compounds

Cat No. Product Name Synonyms Targets
T8730 BMS986260 TGF-beta/Smad
BMS-986260 is a selective, and orally bioavailable TGFβR1 inhibitor(IC50 = 1.6 nM).
T0125 Epirubicin hydrochloride Pharmorubicin,4'-epidoxorubicin HCl,Epirubicin HCl,4'-Epidoxorubicin hydrochloride Apoptosis , DNA/RNA Synthesis , Topoisomerase
Epirubicin hydrochloride (Pharmorubicin) is an antineoplastic agent which can inhibit Topoisomerase.
TP1433 CMD178 TFA STAT
CMD178 (TFA) is a lead peptide that consistently reduces the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling.
T30077 Anisperimus LF 150195,LF-150195,LF 15-0195,LF-15-0195,LF15-0195 Caspase
Anisperimus (LF 15-0195) is an immunosuppressant that enhances activation-induced T-cell death by promoting caspase-8 and caspase-10 activation at the DISC level, and prevents CNS autoimmunity by promoting the developmen...
T2247 KenPaullone 9-Bromopaullone,NSC-664704 GSK-3 , CDK
KenPaullone (9-Bromopaullone), a potent CDK1, CDK2 and CDK5 inhibitor, as new enhancer for iTreg cell differentiation. Kenpaullone promotes iTreg cell differentiation through increased and prolonged transcription of foxp...
TN6393 Fulvotomentoside A Others
Fulvotomentoside A could decrease overexpression of IL-6 and IL-17A, and increase the expression of specific transcription factor Foxp3 of regulatory T cells significantly in intestine. It may be one of the mechanisms th...
T8378 AS2863619 CDK , STAT
AS2863619 is an orally active inhibitor of cyclin-dependent kinase 8 (CDK8) and CDK19 (IC50s of 0.61 nM and 4.28 nM, respectively).
T3S1967 (S)-Indoximod N-ME-Tryptophan,Abrine,L-Abrine Others , Indoleamine 2,3-Dioxygenase (IDO)
(S)-Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse L...
T10382 AS2863619 free base CDK
AS2863619 free base enables the conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells. It is a potent, orally active CDK8 and CDK19 inhibitor (IC50s: 0.61 nM and 4.28 nM). STAT5 act...
TP1770 CMD178
CMD178 is an important polypeptide that consistently reduces the expression of Foxp3 and STAT5 by inhibiting the IL-2/s IL-2Rα signaling pathway.
T15169 DS-437 Others
DS-437 is a dual PRMT5/7 inhibitor (IC50s: 6 μM). DS-437 also inhibits DNMT3A and DNMT3B (IC50s: 52 and 62 μM). DS-437 inhibits the methylation of FOXP3.
T69093 Epirubicin IMI-28,4-epi DX,4'-Epidoxorubicin,IMI 28,4-epidoxorubicin,epi DX,4-epiadriamycin
Epirubicin (4'-Epidoxorubicin), a semisynthetic L-arabino derivative of doxorubicin, serves as an antineoplastic agent primarily by inhibiting Topoisomerase, thereby impeding DNA and RNA synthesis. Additionally, it funct...
TargetMol