depsipeptide — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6006	Romidepsin	FR 901228,FK 228,Depsipeptide,NSC 630176	Apoptosis , HDAC
	Romidepsin (FR 901228) is an HDAC inhibitor that inhibits HDAC1/2/4/6 (IC50=36/47/510/1400 nM). Romidepsin has antitumor activity and can be used for the treatment of peripheral T-cell lymphoma and cutaneous T-cell lymph...		Apoptosis , HDAC
T25327	Didemnin B	NSC 325319,NSC325319,NSC-325319,Didemnin-B	Antiviral
	Didemnin B (Didemnin-B) is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum that has antiviral and antitumor activity.		Antiviral
TP1072	Valinomycin	NSC 122023	Apoptosis , PTEN , Antibacterial , Antibiotic , Autophagy
	Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes Parkin phosphorylation at Ser65.		Apoptosis , PTEN , Antibacterial , Antibiotic , Autophagy
T26175	Salinamide A
	Salinamide A is an effective anti-inflammatory bicyclic depsipeptide.
T25326	Didemnin A	NSC325319,NSC-325319,NSC 325319,Didemnins
	Didemnin A is an antiviral and antitumor depsipeptide from Carribean tunicate.
T28943	Telomycin	A-128,A 128,A128,NSC 235069,Antibiotic 128
	elomycin is a cyclic depsipeptide antibiotic with activity against Gram-positive bacteria.
T34717	Stevastelin B3	NK374186B3,NK 374186B3,Antibiotic NK 374186B3,NK-374186B3
	Stevastelin B3 is a depsipeptide isolated from Penicillium.
T15158	Dolastatin 15	DLS 15	Others
	Dolastatin 15, a depsipeptide derived from Dolabella auricularia, is a potent antimitotic agent structurally related to the anti-tubulin agent Dolastatin 10. Dolastatin 15 can be used as an ADC cytotoxin and it induces c...		Others
T68351	Homodestcardin
	Homodestcardin is a cyclic depsipeptide fungal metabolite that has been found in T. roseum and has immunosuppressant activity. It inhibits concanavalin A-induced proliferation of isolated mouse T cells.
T16997	Tasidotin hydrochloride	ILX651	Microtubule Associated
	Tasidotin hydrochloride is a peptide analog of the antimitotic depsipeptide dolastatin 15. Tasidotin hydrochloride is an inhibitor of microtubule assembly and microtubule dynamics.		Microtubule Associated
T76000	Aurantimycin A
	Aurantimycin A (Adipogen), a depsipeptide antibiotic, exhibits potent efficacy against Gram-positive bacteria and serves as a substrate for the LieAB transporter [1] [2].
T26456	A 83586C	A83586C,A-83586C
	A-83586C is a depsipeptide antibiotic from Streptomyces karnatakensis with potent against Gram-positive activity in vitro. A-83586C acts as a highly potent inhibitor of beta-catenin/TCF4 signaling within cancer cells, wh...
T36598	Enopeptin A
	Enopeptin A, originally isolated from a culture broth of Streptomyces sp. RK-1051, is a depsipeptide antibiotic that contains two unusual amino acids (N-methylalanine and 4-methylproline) and features a pentaenone side c...
T36181	Quinaldopeptin
	Quinaldopeptin is a quinomycin antibiotic. It is active against a variety of bacteria, including S. pyogenes, S. aureus, C. perfringens, S. faecalis, E. coli, and K. pneumoniae (MICs = 0.2, 0.4, 0.8, 1.6, 3.1 and 6.3 μg/...
T82479	Elisidepsin	PM02734
	Elisidepsin (PM02734), a cyclic depsipeptide, exhibits antineoplastic activity by inhibiting cancer cell proliferation and is under research for the treatment of various cancers, including non-small cell lung cancer (NSC...
T76506	Coibamide A
	Coibamide A, an N-methyl-stabilized cytotoxic depsipeptide, exhibits potent antiproliferative activity alongside inducing autophagosome accumulation through an mTOR-independent mechanism and triggering apoptosis. Additio...
T36096	Thiocoraline
	Thiocoraline is a depsipeptide and DNAbis-intercalator originally isolated fromMicromonosporawith antibacterial and anticancer activities.1,2It is active against the Gram-positive bacteriaS. aureus,B. subtilis, andM. lut...