7-51a

7-51A is an effective inhibitor of the PB2 subunit of the influenza RNA-dependent RNA polymerase (RdRP), with a dissociation constant (K_D) of 1.64 nM as determined by isothermal titration calorimetry (ITC).

Selisistat (EX-527) is a potent and specific inhibitor of the deacetylase SIRT1 (IC50 = 38 nM) and can be utilized in the study of neurological disorders such as Huntington's chorea.

Compound Fr13429, with CAS No. 1486-51-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13429 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound PDK0413, with CAS No. 945-51-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0413 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr13380, with CAS No. 55695-51-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13380 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr16668, with CAS No. 89795-51-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr16668 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound 224311-51-7, with CAS No. 224311-51-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound 224311-51-7 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

E 6080 HCl is a 5-lipoxygenase inhibitor and can be used to study bronchial diseases.

Panglimycin C is a useful organic compound for research related to life sciences. The catalog number is T126547 and the CAS number is 1005178-51-7.

W-7 hydrochloride (W-7 HCl), a calmodulin antagonist, inhibits Ca2+-calmodulin-dependent myosin light chain kinase and phosphodiesterase, W-7 hydrochloride induces apoptosis and has antitumor activity.

Gly-Arg-AMC is a fluorogenic substrate for cathepsin C.1 Upon enzymatic cleavage by cathepsin C, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify cathepsin C activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively. |1. Rubach, J.K., Cui, G., Schneck, J.L., et al. The amino-acid substituents of dipeptide substrates of cathepsin C can determine the rate-limiting steps of catalysis. Biochemistry 51(38), 7551-7568 (2012).

RAS inhibitor Abd-7 is a powerful compound (Kd=51 nM) that binds to RAS and inhibits the protein-protein interaction (PPI) between RAS and its effectors. By interacting with RAS within cells, RAS inhibitor Abd-7 hinders RAS-effector interactions and suppresses endogenous RAS-dependent signaling. Additionally, RAS inhibitor Abd-7 disrupts the PPI of different mutant KRAS proteins with PI3K, CRAF, RALGDS, as well as NRAS Q61H and HRAS G12V[1].

Antibacterial agent 51 (example 45) is a potent antibacterial compound effective against E. coli strains NCTC 13351, M 50, and 7 MP, with MIC values of 4, 8, and 8 mcg/mL, respectively [WO2013030733A1].

1-(4,5-Dihydro-1H-1,5-methanobenzo[d]azepin-3(2H)-yl)-2,2,2-trifluoroethanone is a useful organic compound for research related to life sciences. The catalog number is T66324 and the CAS number is 230615-51-7.

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(tritylthio)propanoic acid is a useful organic compound for research related to life sciences. The catalog number is T66486 and the CAS number is 944797-51-7.

α-Isonitrosopropiophenone is a useful organic compound for research related to life sciences. The catalog number is T67150 and the CAS number is 119-51-7.

Compound 5K (Multi-target kinase inhibitor 2) is a multi-targeted kinase inhibitor demonstrating activity against EGFR, Her2, VEGFR2, and CDK2 with IC50 values between 40 to 204 nM. It exhibits cytotoxic effects on HepG2, HeLa, MDA-MB-231, and MCF-7 cell lines, with IC50 values of 41, 57, 51, and 59 μM, respectively. Additionally, it induces cell cycle arrest and apoptosis specifically in HepG2 cells.

Lomefloxacin-d5 hydrochloride is a deuterated compound of Lomefloxacin hydrochloride. Lomefloxacin hydrochloride has a CAS number of 98079-51-7. Lomefloxacin is a synthetic broad-spectrum fluoroquinolone with antibacterial activity.

3,21-Dihydroxy-14-serraten-16-one is a natural product for research related to life sciences. The catalog number is TN2859 and the CAS number is 24513-51-7.

Daturataturin A is a natural product of Datura, Solanaceae. The catalog number is TN3776 and the CAS number is 133360-51-7. Daturataturin A can be used as a reference standard.

Pedicin is a natural product for research related to life sciences. The catalog number is TN4746 and the CAS number is 521-51-7.

2,3-Dihydroamentoflavone is a natural product for research related to life sciences. The catalog number is TN5490 and the CAS number is 34340-51-7.