5-fam

5-FAM (5-Carboxyfluorescein) (5-Carboxyfluorescein) contains a carboxylic acid, which can be used to react with primary amines via carbodiimide activation of the carboxylic acid. Fluorescein is the most common fluorescent derivatization reagent for labeling biomolecules. In addition to its excellent fluorescence quantum yield, relatively high absorptivity, and good water solubility, it also has an excitation maximum that closely matches the 488 nm spectral line of the argon-ion laser.

5-FAM SE is a single isomer widely employed in the preparation of various small fluorescent molecules. It is a highly popular green fluorescent reagent used for labeling peptides, proteins, and nucleotides [5-FAM SE].

5-FAM-Ahx-LL-37 TFA is a 5-FAM labeled version of LL-37, human. The carboxyfluorescein moiety is attached via 6-Aminohexanoic acid (Ahx). LL-37, human, is a 37-residue amphipathic antimicrobial peptide, derived from an antibiotic, possessing broad-spectrum antimicrobial activity.

5-FAM-LL-37 TFA is the TFA salt form of 5-FAM-LL-37. This fluorescein-labeled LL-37 peptide maintains the antimicrobial and immunomodulatory properties of LL-37. It binds to bacterial cell membranes, disrupting their integrity, and exhibits broad-spectrum antibacterial activity.

5-FAM-NH2.HCl is a derivative fluorescent dye of 5-FAM. 5-FAM (5-Carboxyfluorescein) is a green fluorescent probe and fluorescein derivative used for labelling peptides, proteins, and nucleic acids, with excitation/emission wavelengths of 490/520 nm.

5-FAM-Dyrktide is a Dyrktide compound labeled with 5-FAM. This substrate undergoes effective phosphorylation by DYRK1A (Km=35 μM) while remaining resistant to phosphorylation by ERK2.

5-FAM-PMDM6 (PMDM6-F) is a biologically active peptide. It serves as a fluorescently labeled probe used in MDM2 binding assays.

5-FAM-β-Amyloid (1-28) is a peptide labeled with a fluorescent probe, representing the initial 28 amino acids of the β-Amyloid protein.

5-FAM maleimide, a derivative of 5-FAM, can be utilized for protein labeling [1].

5-FAM-LPETGG is a fluorescent peptide that combines the sortase recognition sequence LPETGG with the fluorescent label 5-carboxyfluorescein (5-FAM), characterized by excitation/emission maxima at 492/518 nm. It serves for site-specific labeling of target proteins through sortase-catalyzed transpeptidation.

5-FAM-LL-37 is a fluorescently labeled antimicrobial peptide conjugated to 5-carboxyfluorescein (5-FAM) through a 6-aminohexanoic acid (Ahx) linker, featuring excitation/emission maxima at 492/518 nm, respectively. This compound integrates the functional attributes of LL-37 with the fluorescent properties of 5-FAM for enhanced visualization.

5-FAM-GpYLPQTV-NH2, a fluorescently labeled peptide, exhibits STAT3 inhibitory activity and is applicable in cancer research [1].

5(6)-FAM SE (5(6)-Carboxyfluorescein N-hydroxysuccinimide ester) is an amine-reactive green fluorescent dye. 5(6)-FAM SE is widely used for labeling proteins or other molecules that contain a primary or secondary aliphatic amine.

FAM amine, 5-isomer is a fluorescein linker capable of undergoing enzymatic transamination reactions. The addition of an amine group enhances the compound's reactivity with carboxylic acids, activated NHS esters, and other carbonyl groups.

FAM tetrazine, 5-isomer, is a versatile dye featuring a terminal tetrazine group. The terminal methyl tetrazine group can undergo a rapid click reaction with TCO (trans-cyclooctene).

FAM hydrazide, 5-isomer is a fluorescein dye linker that contains a hydrazide functional group. Fluorescein is a versatile dye, and the hydrazide moiety reacts with aldehydes to form a semi-permanent hydrazone bond.

FAM azide, 5-isomer, is a reagent used for Click Chemistry labeling.

FAM phosphoramidite, 5-isomer, is a standard fluorescein (FAM) phosphoramidite used for 5' end labeling of oligonucleotides with a high-purity single isomer.

5-diacetate FAM NHS (5-CFDA SE) is a cell-permeable fluorescent tracer for use in fluorescence microscopy and flow cytometry, Ex=492 nm, Em=517 nm.

CY5-SE (Cy5 NHS Ester) is a reactive dye used to label amino groups in peptides, proteins and nucleotides. It needs to be stored away from light. Excitation wavelength (nm): 640, emission wavelength (nm): 664.

CFSE (CFDA-SE) is a fluorescent dye with cell membrane permeability. CFSE irreversibly binds to intracellular proteins in living cells and is used for the detection of cell proliferation. The labeled cells fluoresce in green color with excitation wavelength of 488 nm and emission wavelength of 518 nm.

Alexa fluor 647 NHS ester (L-5-Hydroxytryptophan-d3) is a photostable far-red fluorescent dye used in imaging and flow cytometry to generate stable signals for protein labeling, amine-modified oligonucleotides, and other primary amine-containing molecules.

FFN 102 mesylate is a pH responsive fluorescent false neurotransmitter (FFN), a selective dopamine transporter (DAT) and VMAT2 substrate. Exhibits no significant binding to a panel of 38 CNS receptors, including dopamine and serotonin receptors. Inhibits dopamine uptake. Excitation maxima are 340 nm at pH 5 and 370 nm at pH 7.5. Emission maximum is 435 nm at both pH 5 and 7.5.FFN 102 mesylate is a Ph-responsive fluorescent pseudoneurotransmitter (FFN) that acts as a substrate for selective dopamine transporters (DAT) and VMAT2.

C12FDG (5-Dodecanoylaminofluorescein di-beta-D-Galactopyranoside) is used as a lipophilic green fluorescent substrate for detecting beta-galactose activity, a green fluorescent substrate, is a senescence marker and is often used in conjunction with flow cytometry.