5-a-ru

5-A-RU (5-Amino-6-(D-ribitylamino)uracil) is an early intermediate in riboflavin biosynthesis and is found in a variety of bacteria and yeast as well as plants. 5-A-RU is also a mucosal-associated invariant T (MAIT) cell activator that forms potent MAIT-activating antigens through non-enzymatic reactions with small molecules from other metabolic pathways.

5-A-RU hydrochloride (5-Amino-6-(D-ribitylamino)uracil hydrochloride) is a metabolic intermediate, a MAIT cell activator that activates mucosal-associated invariant T cells, and is used for research on breast cancer and prostate cancer.

5-A-RU-PABC-Val-Cit-Fmoc is a precursor of 5-A-RU, a small molecule activator associated with mucosal-associated invariant T (MAIT) cells and a precursor in bacterial riboflavin synthesis.

5-OP-RU belongs to immunomodulators and is an MR1-dependent MAIT cell agonist with the characteristic of efficiently activating and enriching mucosal-associated invariant T (MAIT) cells. This compound can be used as a mucosal adjuvant in research on Mycobacterium tuberculosis infection.

6PGD-IN-2 is a non-competitive inhibitor of 6-phosphogluconate dehydrogenase (6PGD) with an IC50 value of 5.1 μM. It disrupts 6PGD oligomerization in a substrate-dependent manner and induces the production of NADPH and Ru-5-P while reducing DNA synthesis in A549 cells. 6PGD-IN-2 is applicable in research on non-small cell cancer and liver cancer.

[Ru(dpp)(bpy)(mtmp)](PF6)2 (Compound 5) is a ruthenium-based coordination complex with three chelating ligands. It exhibits photoactivated anticancer properties. Under green light irradiation, [Ru(dpp)(bpy)(mtmp)](PF6)2 selectively cleaves, releasing a phototoxic ruthenium-based product that binds to nuclear DNA, inducing DNA damage and apoptosis in cancer cells. This compound is applicable for phototherapy research on cancers such as conjunctival melanoma.

RU 24969 is a selective agonist at the 5-HT1A and 5-HT1B receptors.

5'-O-DMT-rU is a modified nucleoside used for RNA synthesis.

RU 24969 succinate, a 5-HT receptor agonist, exhibits K i values of 0.38 nM for 5-HT 1B and 2.5 nM for 5-HT 1A, indicating its affinity towards these receptors. It reduces fluid consumption and enhances forward locomotion. This compound is utilized in neurological disease research.

RU 24969 (5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole) is a selective agonist of 5-HT1A and 5-HT1B receptors.

2'-O-MOE-5-Me-rU is a nucleoside derivative featuring a 2'-modified nucleoside.

DMTr-S-5-C-Me-2'-O-Me-rU-3'-CE-phosphoramidite serves as a monomeric building block for nucleic acid synthesis.

5'-O-DMTr-2'-O-(2-cyanoethoxymethyl)-rU is a monomer precursor utilized in nucleic acid synthesis.

DMTr-2'-O-TBDMS-5-F-rU-3'-CE-phosphoramidite serves as a monomeric raw material for nucleic acid synthesis.

5'-O-DMTr-2'-O-(2-Aminoethyl)-5-Me-rU is a monomeric material utilized in the synthesis of nucleic acids.