5-a-ru

5-A-RU (5-Amino-6-(D-ribitylamino)uracil) is an early intermediate in riboflavin biosynthesis and is found in a variety of bacteria and yeast as well as plants. 5-A-RU is also a mucosal-associated invariant T (MAIT) cell activator that forms potent MAIT-activating antigens through non-enzymatic reactions with small molecules from other metabolic pathways.

5-A-RU hydrochloride (5-Amino-6-(D-ribitylamino)uracil hydrochloride) is an intermediate of bacterial riboflavin that activates mucosal-associated invariant T cells (MAIT).5-A-RU is used in the study of breast and prostate cancer.

5-A-RU-PABC-Val-Cit-Fmoc is a precursor of 5-A-RU, a small molecule activator associated with mucosal-associated invariant T (MAIT) cells and a precursor in bacterial riboflavin synthesis.

5-OP-RU is a MAIT-activating ligand, the major antigen of MAIT cells, a mucosal adjuvant, induces efficient enrichment of mucosal-associated invariant T cells, and can be used to study Mycobacterium tuberculosis infections.

6PGD-IN-2 is a non-competitive inhibitor of 6-phosphogluconate dehydrogenase (6PGD) with an IC50 value of 5.1 μM. It disrupts 6PGD oligomerization in a substrate-dependent manner and induces the production of NADPH and Ru-5-P while reducing DNA synthesis in A549 cells. 6PGD-IN-2 is applicable in research on non-small cell cancer and liver cancer.

5'-O-DMT-rU is a modified nucleoside used for RNA synthesis.

RU 24969 (5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole) is a selective agonist of 5-HT1A and 5-HT1B receptors.

2'-O-MOE-5-Me-rU is a nucleoside derivative featuring a 2'-modified nucleoside.