αlipoic acid

α-Lipoic acid-NHS is an alkyl/ether-based PROTAC linker used in the synthesis of PROTACs [1].

Alpha-Lipoic Acid Choline Ester is used potentially to treat presbyopia.

Andrographolide-lipoic acid is an analogue of Andrographolide, synthesized through the conjugation of Andrographolide and Lipoic acid. It inhibits NF-κB and exhibits anti-diabetic effects as well as protective effects on β-cells.

Mannosamine-lipoic acid adduct functions as a hapten. The conjugate of Mannosamine-lipoic acid adduct with hsIgG effectively reduces the antibody immune response to hsIgG.

Lipoic acid (R-(+)-Thioctic acid) is an organosulfur compound derived from octanoic acid. It is made in animals normally, and is essential for aerobic metabolism.

α-Lipoic Acid (DL-α-Lipoic acid) an octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.

Dihydrolipoic acid (USAF XR-12), a dithiol-containing carboxylic acid, acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including peroxynitirite, hydroxyl radicals, hydrogen peroxide, and hypochlorite, at concentrations ranging from 0.01-0.5 mM.

(R)-Dihydrolipoic acid is a R-isomer of Dihydrolipoic acid. It is optically active, but only the R-enantiomer is biochemically significant. The lipoic acid/dihydrolipoic acid pair participate in a variety of biochemical transformations.

α-Lipoic Acid sodium (Thioctic acid sodium) is an antioxidant and essential cofactor for mitochondrial enzyme complexes. It inhibits NF-κB-dependent HIV-1 replication, induces endoplasmic reticulum stress-mediated apoptosis in hepatocellular carcinoma cells, and modulates SREBP-1, FOXO1, and Nrf2 to improve high-fat diet-induced hepatic steatosis.

α-Lipoic Acid-d5 is the deuterated form of α-Lipoic Acid. It serves as a significant antioxidant and an essential cofactor in mitochondrial enzyme complexes. α-Lipoic Acid has the ability to inhibit NF-κB-dependent HIV-1LTR activation and induces apoptosis in liver cancer cells (apoptosis) mediated by endoplasmic reticulum stress (ERS).

α-Lipoic Acid-D5 (Standard) is a reference standard of α-Lipoic Acid-D5 intended for quantitative analysis, quality control, and related biochemical research applications. α-Lipoic Acid-d5 is the deuterated form of α-Lipoic Acid. It serves as a significant antioxidant and an essential cofactor in mitochondrial enzyme complexes. α-Lipoic Acid has the ability to inhibit NF-κB-dependent HIV-1LTR activation and induces apoptosis in liver cancer cells (apoptosis) mediated by endoplasmic reticulum stress (ERS).

(S)-Thioctic acid [(S)-lipoic acid; (S)-5-(1,2-Dithiolan-3-yl)pentanoic acid] is a biochemical reagent that can be used as a biomaterial or an organic compound in life science research.