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By Target- Endogenous Metabolite
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Results for "
α-ketoglutarate dehydrogenase
" in TargetMol Product Catalog- Inhibitors & Agonists8
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α-Lipoic Acid
Thioctic acid, DL-α-Lipoic acid, (±)-α-Lipoic acid
T02001077-28-7
α-Lipoic Acid (DL-α-Lipoic acid) an octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
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Succinyl phosphonate
T1302026647-82-5
Succinyl phosphonate is a selective α-ketoglutarate dehydrogenase (α-KGDHC ) and OGDHC inhibitor that inhibits α-ketoglutarate oxidative decarboxylation. Succinyl phosphonate trisodium salt inhibits glutamate-induced ROS generation in glutamate-stimulated hippocampal neurons and can be used to study neurodegenerative diseases.
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